CT guided lung biopsy complications: a single centre prospective study

Authors

  • Mohd Farooq Mir Department of Radiodiagnosis and Imaging, SKIMS MCH, Srinagar, Jammu and Kashmir, India
  • Muzafar Ahmed Naik Department of General Medicine, SKIMS MCH, Srinagar, Jammu and Kashmir, India
  • Javid Ahmed Malik Department of Chest Medicine, SKIMS MCH, Srinagar, Jammu and Kashmir, India

DOI:

https://doi.org/10.18203/2320-6012.ijrms20183416

Keywords:

CT-guided biopsy, Pneumothorax, Pulmonary haemorrhage

Abstract

Background: Computed tomography (CT) guided percutaneous transthoracic needle biopsy of lung is a routine procedure in patients with suspected malignant lung lesions which are either peripheral or not amenable to biopsy on fibreoptic bronchoscopy.

Methods: This prospective study was conducted to obtain complication rates based on patient and physician experience after CT guided lung biopsy of central and peripheral lung lesions.

Results: In our study 96 patients were included with 78 patients with peripheral and 18 patients having central lung lesions. The reported post procedural complication rates of CT guided lung biopsy were pulmonary haemorrhage 33.3 %, pneumothorax 21.9%, haemoptysis 15.6%, cough 6.3%, haemothorax 3.1% and fever 3.1%. Two patients required inter costal tube drainage. There was no reported mortality of CT guided lung biopsy in our centre.

Conclusions: Pulmonary haemorrhage and pneumothorax are the most common complications of percutaneous transthoracic needle biopsy of the lung, the former one is common with central and the latter one with peripheral lung lesions.

References

Covey AM, Gandhi R, Brody LA, Getrajdman G, Thaler HT, Brown KT. Factors associated with pneumothorax and pneumothorax requiring treatment after percutaneous lung biopsy in 443 consecutive patients. J Vasc Interv Radiol. 2004;15:479-83.

Saji H, Nakamura H, Tsuchida T, Tsuboi M, Kawate N, Konaka C, et al. The incidence and the risk of pneumothorax and chest tube placement after percutaneous CT-guided lung biopsy: the angle of the needle trajectory is a novel predictor. Chest. 2002 May 1;121(5):1521-6.

Yeow KM, Su IH, Pan KT, Tsay PK, Lui KW, Cheung YC, et al. Risk factors of pneumothorax and bleeding: multivariate analysis of 660 CT-guided coaxial cutting needle lung biopsies. Chest. 2004 Sep 1;126(3):748-54.

Khan MF, Straub R, Moghaddam SR, Maataoui A, Gurung J, Wagner TO, et al. Variables affecting the risk of pneumothorax and intrapulmonal hemorrhage in CT-guided transthoracic biopsy. European radiology. 2008 Jul 1;18(7):1356-63.

Fish GD, Stanley JH, Miller KS, Schabel SI, Sutherland SE. Postbiopsy pneumothorax: estimating the risk by chest radiography and pulmonary function tests. Am J Roentgenol. 1988 Jan 1;150(1):71-4.

Tomiyama N, Yasuhara Y, Nakajima Y, Adachi S, Arai Y, Kusumoto M, et al. CT-guided needle biopsy of lung lesions: a survey of severe complication based on 9783 biopsies in Japan. Euro J radiology. 2006 Jul 1;59(1):60-4

Heyer CM, Reichelt S, Peters SA, Walther JW, Müller KM, Nicolas V. Computed tomography-navigated transthoracic core biopsy of pulmonary lesions: which factors affect diagnostic yield and complication rates? Acad Radiol. 2008;15:1017-26.

Pearce JG, Patt NL. Fatal pulmonary hemorrhage after percutaneous aspiration lung biopsy. Am Rev Respir Dis. 1974;110:346-9.

Neyaz Z, Lal H, Thakral A, Nath A, Rao RN, Verma R. Percutaneous computed tomography-guided aspiration and biopsy of intrathoracic lesions: Results of 265 procedures. Lung India: official organ Indian Chest Society. 2016;33(6):620.

Chellathurai A, Kanhirat S, Chokkappan K, Swaminathan TS, Kulasekaran N. CT-guided biopsy of lung masses using an automated guiding apparatus. Ind J Radiol Imaging. 2009;19(3):206-7.

Lang D, Reinelt V, Horner A, Akbari K, Fellner F, Lichtenberger P, et al. Complications of CT-guided transthoracic lung biopsy. Wiener klinische Wochenschrift. 2018;130(7-8):1-5.

Winn N, Spratt J, Wrigh E, Cox J. M Patient reported experiences of CT guided lung biopsy: a prospective cohort study. Multidiscip Respir Med. 2014; 9(1): 53.

Gupta S, Wallace MJ, Cardella JF, Kundu S, Miller DL, Rose SC. Quality improvement guidelines for percutaneous needle biopsy. J Vasc Interv Radiol. 2010;21:969-75.

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Published

2018-08-25

How to Cite

Mir, M. F., Naik, M. A., & Malik, J. A. (2018). CT guided lung biopsy complications: a single centre prospective study. International Journal of Research in Medical Sciences, 6(9), 2943–2947. https://doi.org/10.18203/2320-6012.ijrms20183416

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Original Research Articles