A rare case report of acute necrotizing pancreatitis being the sole extra-pulmonary manifestation of COVID-19
DOI:
https://doi.org/10.18203/2320-6012.ijrms20213229Keywords:
COVID-19, Acute necrotizing pancreatitis, Viral pancreatitis, Extra-pulmonary manifestationAbstract
The current pandemic of Corona virus disease (COVID) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Commonly the disease presents as symptoms suggestive of upper respiratory tract infection to severe acute respiratory infection syndrome (SARI). However various extra-pulmonary manifestations related to gastrointestinal system and hepatobiliary system including acute pancreatitis have been reported quite frequently. Here we report a case of COVID-19 who presented with acute necrotizing pancreatitis without any respiratory symptoms.
References
Gupta A, Madhavan MV, Sehgal K, Nair N, Mahajan S, Sherawat TS et al. Extrapulmonary manifestations of COVID-19. Nat Med. 2020;26:1017-32.
Zhu N, Zhang D, Wang W, Li X, Yang B, Song J et al. A novel coronavirus from patients with pneumonia in China, 2019. N Engl J Med. 2020;382:727-33.
Guan WJ, Ni ZY, Hu Y, Liang WH, Ou CQ, He JX et al. Clinical characteristics of coronavirus disease 2019 in China. N Engl J Med. 2020;382:1708e-20.
Goodchild G, Chouhan M, Johnson GJ. Practical guide to the management of acute pancreatitis. Frontline Gastroenterol. 2019;10:292-9.
Simons-Linares CR, Imam Z, Chahal P. Viral-Attributed acute pancreatitis: a systematic review. Dig Dis Sci. 2020;143.
Matheson NJ, Lehner PJ. How does SARS-CoV-2 cause COVID-19? Science 2020;369:510-1.
De-Madaria E, Capurso G. COVID-19 and acute pancreatitis: examining the causality. Nat Rev Gastroenterol Hepatol. 2021;18:3-4.
Liu F, Long X, Zhang B, Zhang W, Chen X, Zhang Z et al. ACE2 expression in pancreas may cause pancreatic damage after SARS-CoV-2 infection. Clin Gastroenterol Hepatol. 2020;18:2128-30.
Schepis T, Larghi A, Papa A, Miele L, Panzuto F, Biase LD et al. SARS-CoV2 RNA detection in a pancreatic pseudocyst sample. Pancreatology. 2020;20:1011-2.
Gonzalo-Voltas A, Fernández-Pérez-Torres CU, Baena-Díez JM. Acute pancreatitis in a patient with COVID-19 infection. Med Clin. 2020;155:183-4.
Wang F, Wang H, Fan J, Zhang Y, Wang H, Zhao Q et al. Pancreatic injury patterns in patients with coronavirus disease 19 pneumonia. Gastroenterology. 2020.