Clinicopathological features of uterine fibroid in a tertiary care teaching hospital
DOI:
https://doi.org/10.18203/2320-6012.ijrms20213943Keywords:
Uterine leiomyoma, Pathological changes, Hysterectomy, DegenerationAbstract
Background: Uterine fibroids are one of the common benign tumours of uterus seen in women of reproductive age group. These constitute 5-10% of all these tumours.
Methods: Total of 56 patients above 21 years of age reporting to OPD or emergency of gynaecology department of the Mayo Institute and found to be suffering from leiomyoma of the uterus were included in the study.
Results: Clinical manifestations seen in cases with uterine fibroid. Menstrual irregularities were seen in 69.64% of cases. 39.28% suffered from abdominal pain and infertility was seen in 10.71% cases. Endometrial changes during the histopathological examination. In 71.42% of cases, proliferative endometrium was found. Secretory endometrium was seen in 14.28% and atrophic in 8.92%.
Conclusions: Leiomyoma is the most well-known uterine tumor seen in gynecological practice. Feminine aggravations are the commonest manifestation of which menorrhagia is the most well-known show. The vast majority of these tumors are intramural in area. The most widely recognized example of endometrium noticed is proliferative. Hyaline degeneration, myxoid degeneration and cystic degeneration are the normal auxiliary changes found in fibroid uterus.
References
Crum CP. Body of uterus and endometrium. In: Kumar V, Abbas AK, Fausto N, eds. Robbins and Cotran Pathologic Basis of Disease. 7th ed. Philadelphia: Saunders; 2004: 1089-1090.
Christopher PC. The female genital tract in: Kumar, Abbas, Fauster eds. Robbins and Cottron Pathologic basis of disease. 8th ed. India Elsevier; 2010.
Gowri M, Mala G, Murthy S, Nayak V. Clinicopathological study of uterine leiomyomas in hysterectomy specimens. J Evolut Med Dent Sci. 2013;2(46):9002-9.
Jalandhara J, Mehta K, Desai R, Parakh P, Choudhary G. Clinicopathological study of uterine leiomyomas- A multicentric study in rural population. IJMHR. 2018;4(6):16-8.
Dayal S, Kumar A, Verma A. Clinicopathologic correlation of leiomyoma with clinical findings and secondary changes in a rural population of north India. Am J Clin Pathol. 2014;141(2):275-9.
Subrata P, Srabani C, Anuradha S, Prakash PJ, Kingshuk B, Mrinal S. A retrospective clinicopathological study of hysterectomy cases in a tertiary care hospital in India – a review of 950 cases. Bangladesh J Med Sci. 2018;17(1):88-92.
Lahori M, Malhotra A, Sakul S, Khajuria A, Goswami K. Clinicopathological spectrum of uterine leiomyomas in a state of Northern India a hospital based study. Int J Reprod Contracept Obstet Gynecol. 2016;5(7)2295-9.
Kulkarni MR, Dutta I, Dutta DK. Clinicopathological Study of Uterine Leiomyomas: A Multicentric Study in Rural Population. J Obstet Gynaecol India. 2016 ;66(1):412-6.
Nisolle M, Gillerot S, Casanas-Roux F, Squifflet J, Berliere M, Donnez J. Immunohistochemical study of the proliferation index, oestrogen receptors and progesterone receptors A and B in leiomyomata and normal myometrium during the menstrual cycle and under gonadotrophin-releasing hormone agonist therapy. Hum Reprod. 1999;14(11):2844-50.
Kaur H, Gulati A. Pathophysiology of fibroids. Ind J Pathol Oncol. 2014;1(1):14-7.
Thomason P. Uterine leiomyoma. Medscape. 2017.
Samaila MO, Adesiyun A, Agunbiade O, Mohammed D. A clinicopathological assessment of hysterectomies in Zaria. Eur J Gen Med. 2009;6(3):150-3.
Bhatta S, Bhandari S, Osti BP. Histopathological study of Uterine Leiomyoma in Hysterectomy Specimens. Ann Clin Chem Lab Med. 2018;3(2):16-20.
Zaloudek CJ, Hendrickson MR, Soslow RA. Mesenchymal tumors of uterus. Blaustein Pathology of the female genital tract. 6th ed. Springer; 2011: 459-466.
