DOI: http://dx.doi.org/10.18203/2320-6012.ijrms20214723

Trichosporon species isolated from scald burn wound in an immunocompetent adult: a case report from Southern Assam

Barnamoy Bhattacharjee, Debadatta D. Chanda, Atanu Chakravarty

Abstract


There are quite a good number of case reports on fungal infection in burn wounds in addition to the conventionally notorious bacterial infections in immune-compromised burn trauma patients leading to protracted course of morbidity and higher chances of mortality due to delay in diagnosis. The incidence of fungal infection in burn patients has been increasing with paradigm shift of causal fungus over last 2 decades from Candida albicans and molds to non-albicans Candida, Trichosporon species and other yeast like fungus. But there are rarely few cases of invasive Trichosporon infection in scald burn wounds in immunocompetent individuals. We therefore report a case of Trichosporon species isolation from a scald burn ulcer of an immunocompetent young male industrial worker in 2nd week of its clinical course which responded to oral fluconazole followed by skin grafting since this case scenario in itself is an uncommonly presented and reported event coupled with finding of first ever case with such presentation in this tertiary care institute of Southern Assam. This case is also reported with intention of raising awareness in surgeons for keeping vigil on non-healing burn wounds with empirical antibiotics and about the need of timely pus culture and sensitivity testing to rule out fungal colonization and prevent mortality due to disseminated fungal infection.


Keywords


Trichosporon, Pus culture, Scald burn, Immunocompetent, Assam

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References


Chander J. Text Book of Medical Mycology. 4th edition. ‎ Jaypee Brothers Medical Publishers. 2018.

Hajjeh RA, Blumberg HM. Bloodstream infection due to Trichosporon beigelii in a burn patient: case report and review of therapy. Clin Infect Dis. 1995;20:913-6.

Still JM, Orlet K, Law EJ. Trichosporon beigelii septicaemia in a burn patient. Burns. 1994;20(5);467-8.

Macmillan B, Law E, Holder I. Experience with Candida infections in the burn patient. Arch Surg. 1972;104:509-12.

Kidson A, Lowbury JL. Candida infection of burns. Burns. 1979;8:228-30.

Heslop OD, Nyi MPN, Abbott SP, Rainford LE, Castle DM, Coard KCM. Disseminated Trichosporonosis in a Burn Patient: Meningitis and Cerebral Abscess Due to Trichosporon asahii. J Clin Microbiol. 2011;9:4405-8.

Sarabahi S, Tiwari VK, Arora S, Capoor MR, Pandey A. Changing pattern of fungal infection in burn patients. Burns. 2012;38:520-8.

Lomasa LT, Gonzálezb MDG, Luengoa AIM, Bouzab JME, Pérez JMP. Nosocomial infection due to Trichosporon asahii in a critical burned patient. Rev Iberoam Micol. 2015;32(4):257-60.

Sharma S, Bajaj D, Sharma P. Fungal Infection in Thermal Burns: A Prospective Study in a Tertiary Care Centre. J Clin Diagnost Res.2016;10(9):5-7.

Gardenier JC, Chopra VK, Filicori F, Murphy J, Greenway A, Gallagher JJ, Bessey PQ, Houng A, Eachempati SR, Barie PS. Angioinvasive mold in the surgical and burn intensive care unit: A case series and review of the literature. Surg Infect Case Rep. 2016;1:1:72-8.

Cawley MJ, Braxton GR, Haith LR, Reilly KJ, Guilday RE, Patton ML. Trichosporon beigelii infection: experience in a regional burn Center. Burns. 2000;26:483-6.

Bruck HM, Nash G, Foley FD, Pruitt BA. Opportunistic Fungal infection of burn wound with phycomycetes and aspergillus. A Clinical-pathological review. Arch Surg. 1971;102:476.

Still JM, Law EJ, Belcher KE, Spencer SA. A comparison of susceptibility to five antifungal agents of yeast cultures from burn patients. Bums. 1995;21(3):167-70.