Prevalence of pre-diabetes in adolescents aged 11-17 years with high risk factors

Authors

  • Kuppan Balamurugan Department of Pediatrics, Government Villupuram Medical College Hospital, Villupuram, Tamil Nadu, India
  • Rajangam Ponprabha Department of Pediatrics, Government Villupuram Medical College Hospital, Villupuram, Tamil Nadu, India
  • Veeramani Sivashankari Department of Pediatrics, Government Villupuram Medical College Hospital, Villupuram, Tamil Nadu, India

DOI:

https://doi.org/10.18203/2320-6012.ijrms20214461

Keywords:

Acanthosis nigricans, Adolescent, Obesity, Overweight, Pre-diabetes

Abstract

Background: Obesity is a rising global epidemic in children which leads to pre-diabetes and overt diabetes. Identification at early stage helps in early intervention. This study was undertaken to study the prevalence of pre-diabetes in urban school going adolescents aged 11-17 years with high risk factors.

Methods: This was a prospective cross-sectional study conducted in Chennai, India between December 2011 and November 2012. Overweight or obese adolescents in the age group 11-17 years, either with family history of diabetes or acanthosis nigricans or both were included. After obtaining informed consent from parents, history was obtained in pre-tested questionnaire.

Results: 148 adolescents were enrolled in the study (n=148), 71.62% were females, mean weight was 59.54±10.44 kg, mean height was 150.92±8.62 cm, mean BMI was 26.19±3.23 and mean blood glucose was 82.1 mg/dl. 60.81% of subjects were overweight and others obese. Girls had statistically significant higher mean weight and mean BMI than boys. 78.37% had acanthosis nigricans, 47.29% had family history of diabetes, 12.16% had pre-diabetes and the mean blood glucose in pre-diabetics was 104.9 mg/dl. Pre-diabetes was higher in adolescents with family history of diabetes (p=0.038).

Conclusions: Recognition of risk of type 2 diabetes in the asymptomatic pre-diabetes phase needs to be emphasized and targeted screening of high risk children for pre-diabetes seems to be justified. The morbidity and mortality of youth onset type 2 diabetes can be reduced only by early detection and treatment.

Author Biographies

Kuppan Balamurugan, Department of Pediatrics, Government Villupuram Medical College Hospital, Villupuram, Tamil Nadu, India

Assistant Professor,

Department of Pediatrics,

Government Villupuram Medical College and Hospital,

Mundiyampakkam, Villupuram - 605601

Rajangam Ponprabha, Department of Pediatrics, Government Villupuram Medical College Hospital, Villupuram, Tamil Nadu, India

Assistant Professor,

Department of Pediatrics,

Government Villupuram Medical College and Hospital,

Mundiyampakkam, Villupuram - 605601

Veeramani Sivashankari, Department of Pediatrics, Government Villupuram Medical College Hospital, Villupuram, Tamil Nadu, India

Assistant Professor,

Department of Pediatrics,

Government Villupuram Medical College and Hospital,

Mundiyampakkam, Villupuram - 605601

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Published

2021-11-26

How to Cite

Balamurugan, K., Ponprabha, R., & Sivashankari, V. (2021). Prevalence of pre-diabetes in adolescents aged 11-17 years with high risk factors. International Journal of Research in Medical Sciences, 9(12), 3648–3652. https://doi.org/10.18203/2320-6012.ijrms20214461

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Section

Original Research Articles