A cross-sectional study of neutrophil to lymphocyte ratio as a reliable inflammatory index among hypertensives in Government Rajaji Hospital, Madurai

Authors

  • Poihai A. Department of Physiology, Government Medical College, Virudhunagar, Tamil Nadu, India
  • Sivapriya A. Department of Physiology, Government Sivagangai Medical College, Sivagangai, Tamil Nadu, India

DOI:

https://doi.org/10.18203/2320-6012.ijrms20220292

Keywords:

Atherothrombosis, Hypertension, Lymphocyte, Neutrophil, Platelet

Abstract

Background: Hypertension is a major risk factor to the development of atherothrombosis which is of major health concern today. Neutrophils and platelets play a significant role in the development of atherothrombosis leading to cardiovascular events. Presently, neutrophil lymphocyte ratio and platelet lymphocyte ratio which can be easily calculated from complete blood count have been identified as novel systemic inflammation based indices predictive of cardiovascular risk. This study attempted to assess the relationship between neutrophil lymphocyte ratio and platelet lymphocyte ratio with hypertension.

Methods: This cross-sectional study was conducted in 30 hypertensive patients with less than 2 years of duration and in 30 normal healthy adults between ages 40 to 60 years. Anthropometric measurements (height, weight) and blood pressure were measured. Complete blood count was also analyzed. Pearson’s correlation factor (r) was used to analyse quantitative data.

Results: Both neutrophil lymphocyte ratio and platelet lymphocyte ratio showed a significant positive correlation with systolic BP observed by Pearson’s correlation. NLR (r=0.847, p<0.001) and PLR (r=0.209, p<0.009).

Conclusions: Neutrophil lymphocyte ratio (NLR) and platelet lymphocyte ratio (PLR) can be used as reliable parameters in clinical practice and in epidemiological studies as indices of inflammation among hypertensives.

References

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Published

2022-01-29

How to Cite

A., P., & A., S. (2022). A cross-sectional study of neutrophil to lymphocyte ratio as a reliable inflammatory index among hypertensives in Government Rajaji Hospital, Madurai. International Journal of Research in Medical Sciences, 10(2), 458–461. https://doi.org/10.18203/2320-6012.ijrms20220292

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Original Research Articles