Clinico-epidemiological profile and socio-demographic characteristics of COVID-19 patients admitted in a tertiary care teaching hospital in Tamil Nadu: a descriptive longitudinal study

Authors

  • Thiyagarajan Palanichamy Department of Community Medicine, SRM Medical College Hospital & Research Institute, SRM IST (Deemed University), Kattankulathur, Chengalpet, Tamil Nadu, India http://orcid.org/0000-0003-0071-8605

DOI:

https://doi.org/10.18203/2320-6012.ijrms20220293

Keywords:

COVID-19, Clinical, Epidemiology, Characteristics, Tertiary care

Abstract

Background: The World Health Organization (WHO), on 11th March 2020 declared severe acute respiratory syndrome by SARS-CoV-2 virus as pandemic disease and renamed it as COVID-19. The case fatality rate ranges from 1.4 to 2%. Amidst several measures to contain the spread and mortalities it is been increasing from the date of its declaration as Public Health Emergency of Global Importance (PHEGI). Our study was aimed to describe the clinical, epidemiological features and socio-demographic characteristics and their associations among the COVID-19 patients admitted in our corona care centres.

Methods: A descriptive longitudinal study was done on the laboratory confirmed COVID-19 patients treated in our tertiary care hospital’s corona care centres. Socio-demographic characteristics, co-morbidities, exposure history, PPE use were asked. Symptoms, signs, lab findings, treatments and outcomes were followed-up until discharge or death. The frequencies and statistical associations of variables were analysed using computer software.

Results: Out of 145 majority were 21-40 years of age (49.7%) with mean of 40±15.3 years. Majority urban dwellers (76.6%). Smokers and Alcoholics were few (6.9% and 12.4%). 21.4% had health insurance. Mean IP was -7±3.6days. Travel history within 14 days of IP 4.1%. Fever was dominant (82.6%). Prevalence of co-morbidities 50%. Mean duration of hospital stay was 9±3 days. Average gap between diagnosis to negative RT-PCR was 12days. Majority had category 2 treatments (65.5%). Three inpatients died (2.1%). Sex, symptom to RT-PCR test gap, Altered WBC and coagulation profile were showing statistical association with severity.

Conclusions: COVID-19 pandemic currently shows low case fatality rate. Clear transmission dynamics and host factors needed for better prevention and control.

Author Biography

Thiyagarajan Palanichamy, Department of Community Medicine, SRM Medical College Hospital & Research Institute, SRM IST (Deemed University), Kattankulathur, Chengalpet, Tamil Nadu, India

Community Medicine, Associate Professor

References

World Health Organization. Coronavirus disease (COVID-19) pandemic. Available at: https:// www.who.int/emergencies/diseases/novel-coronavirus-2019. Accessed on 20 June 2021.

MyGov Cell. National Informatics Centre, Ministry of Electronics & InformationTechnology, Government of India. IndiaFightsCorona COVID-19. Available at: https://smygov.in/covid-19/. Accessed on 20 June 2021.

Ghinai I. IllinoisCOVID-19 Investigation Team (2020) First known person-to-person transmission of severeacute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the USA. Lancet. 2020;6736(20):30607-3.

Guan W, Ni Z, Hu Y. Clinical characteristics of coronavirus disease 2019 in China. N Engl J Med. 2020;11:24-8.

Zhang JJ, Dong X, Cao YY, Yuan YD, Yang YB, Yan YQ et al. Clinical characteristics of 140 patients infected with SARS-CoV-2 in Wuhan, China. Allergy. 2020;9:11-4.

Zhou P, Yang XL, Wang XG, Hu B, Zhang L, Zhang W et al. A pneumonia outbreak associated with a new coronavirus of probable bat origin. Nature. 2020;579(7798):270-3.

Xiong Y, Sun D, Liu Y, Fan Y, Zhao L, Li X et al. Clinical and high-resolution CT features of the COVID-19 infection: comparison of the initial and follow-up changes. Investig Radiol. 2020;4:12-8.

Gupta N. Clinical and epidemiologic profile of the initial COVID-19 patients at a tertiary care centre in India Monaldi Archives for Chest Disease. 2020;90:1294.

Indian Council of Medical Research, Government of India. COVID-19. Available at: https://icmr.nic.in/content/covid-19. Accessed 20 June 2021.

Holshue ML, DeBolt C, Lindquist S. First case of 2019novel coronavirus in the United States. N Engl J Med. 2020;382:929-36.

Velmurugan A, Veerakumar AM, Parameshwari P. COVID-19: Filling the Gaps in the Natural History of the Disease for Controlling the Pandemic. National Journal of Research in Community. 2020;9(2):61-6.

Mathur R. National ethical guidelines for bio-medical and health research involving human participants. Edition 1. Indian Council of Medical Research. 2017. Chapter 8. Public health research. 2017;101-10.

Wu Z, McGoogan JM. Characteristics of and important lessons from the coronavirus disease 2019 (COVID-19) outbreak in China: Summary of a report of 72 314 cases from the Chinese Center for Disease Control and Prevention. JAMA. 2020;323:1239-42.

Mohan A. Clinico-demographic profile & hospital outcomes of COVID-19 patients admitted at a tertiary care centre in north India. Indian J Med Res. 2020;152:61-9.

Zhou F, Yu T, Du R, Fan G, Liu Y, Liu Z, et al. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: A retrospective cohort study. Lancet. 2020;395:1054-62.

Richardson S, Hirsch JS, Narasimhan M, Crawford JM, McGinn T, Davidson KW, et al. Presenting characteristics, comorbidities, and outcomes among 5700 patients hospitalized with COVID-19 in the New York city area. JAMA. 2020;323:2052-9.

Grasselli G, Zangrillo A, Zanella A, Antonelli M, Cabrini L, Castelli A et al. Baseline characteristics and outcomes of 1591 patients infected with SARS-CoV-2 admitted to ICUs of the Lombardy Region, Italy. JAMA. 2020;323:1574-81.

Kant R. A preliminary study on contact tracing & transmission chain in a cluster of 17 cases of severe acute respiratory syndrome coronavirus 2 infection in Basti, Uttar Pradesh, India. Indian J Med Res. 2020;152:95-9.

Hu Z, Song C, Xu C, Jin G, Chen Y, Xu X et al. Clinical characteristics of 24 asymptomatic infections with COVID-19 screened among close contacts in Nanjing, China. Sci China Life Sci. 2020;63:706-11.

Soni SL, Kajal K. Demographic & clinical profile of patients with COVID-19 at a tertiary care hospital in north India. Indian J Med Res Epub. 2020;2:12-4.

Kayina CA. Epidemiological & clinical characteristics & early outcome of COVID-19 patients in a tertiary care teaching hospital in India: A preliminary analysis. Indian J Med Res. 2020;152:100-04.

Downloads

Published

2022-01-29

How to Cite

Palanichamy, T. (2022). Clinico-epidemiological profile and socio-demographic characteristics of COVID-19 patients admitted in a tertiary care teaching hospital in Tamil Nadu: a descriptive longitudinal study. International Journal of Research in Medical Sciences, 10(2), 462–469. https://doi.org/10.18203/2320-6012.ijrms20220293

Issue

Section

Original Research Articles