Seroprevalence of hepatitis C in haemodialysis patients in tertiary care hospital in Punjab

Authors

  • Jaspal Kaur Department of Microbiology, Government Medical College, Amritsar, Punjab, India
  • Loveena Oberoi Department of Microbiology, Government Medical College, Amritsar, Punjab, India
  • Kanwardeep Singh Department of Microbiology, Government Medical College, Amritsar, Punjab, India
  • Rakesh Chander Department of Medicine, Government Medical College, Amritsar, Punjab, India

DOI:

https://doi.org/10.18203/2320-6012.ijrms20220295

Keywords:

Hepatitis C, Hemodialysis, Seroprevalence

Abstract

Background: Hepatitis C is an emerging infectious disease all over the world especially in the developing countries. HCV is a blood borne virus, well known risk factors include blood transfusion, injection drug abuse, chronic haemodialysis patients. HCV is a single stranded positive sense RNA virus, belongs to family flaviviridae and genus Hepacivirus. Haemodialysis patients are the high risk group due to prolonged vascular access and contaminated equipments.

Methods: The present study was retrospective conducted from June 2019 to 31 July 2020 in the Department of Microbiology, Government Medical College, Amritsar. Clinical, demographic and geographical data of the renal disease patients admitted to the hospital for haemodialysis was recorded and analysed. The patients were tested for HCV by Third Generation ELISA.

Results: In the present study, out of enrolled 186 patients, 12 were HCV positive (0.06%). Prevalence of Hepatitis C infection in haemodialysis patients is   associated with gender distribution more in females (72%) than males (62%), preponderance of HCV infection was observed in age group 41-60 years (69%) followed by 21-40 years (23%),more rural (85%) distribution. Diabetes (19%), hypertension (25%) and chronic kidney disease (63%) were the associated comorbid conditions.

Conclusions: The overall HCV sero prevalence was observed to be 0.06%, this low prevalence can be attributed to the fact that increased awareness regarding the disinfection of dialysis machines by improving the surveillance system of HCV and better education of nurses in dialysis units. HD patients should be routinely screened for HCV infection.

Author Biographies

Jaspal Kaur, Department of Microbiology, Government Medical College, Amritsar, Punjab, India

Microbiology department,AMritsar.

Junior resident

Loveena Oberoi, Department of Microbiology, Government Medical College, Amritsar, Punjab, India

Head of microbiology department,Government  medical college,Amritsar

Kanwardeep Singh, Department of Microbiology, Government Medical College, Amritsar, Punjab, India

Professor of microbiology department, Government medical college, Amritsar

Rakesh Chander, Department of Medicine, Government Medical College, Amritsar, Punjab, India

Associate Professor ,Government medical college,Amritsar

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Published

2022-01-29

How to Cite

Kaur, J., Oberoi, L., Singh, K., & Chander, R. (2022). Seroprevalence of hepatitis C in haemodialysis patients in tertiary care hospital in Punjab. International Journal of Research in Medical Sciences, 10(2), 477–481. https://doi.org/10.18203/2320-6012.ijrms20220295

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Original Research Articles