Unilateral pulmonary agenesis in a child with recurrent respiratory tract infections

Rajib Das, Priti Roy


Pulmonary agenesis is a rare congenital anomaly defined as complete absence of lung parenchyma with its bronchial tree and vasculature. It usually presents in early childhood and may be associated with other congenital abnormalities. Chest X-ray gives a suspicion of this condition which can be further confirmed by computed tomography scan of thorax. Oher investigations like echocardiography and ultrasonography of whole abdomen must be done to rule out associated congenital anomalies. We describe here a case of one month old male who presented with cough and shortness of breath. Chest X-ray showed right sided homogenous opacity which on contrast enhanced computed tomography revealed right sided pulmonary agenesis. Echocardiography showed situs solitus with dextroposition of heart. The child was treated with intravenous antibiotics, moist oxygen and nebulisation with bronchodilators following which there was clinical resolution of symptoms. In conclusion, congenital pulmonary agenesis should be included in the differential diagnosis in a child presenting with dyspnoea and homogenous opacity of unilateral lung field in Chest X-ray for early diagnosis, management and prevention of recurrent respiratory infections and consequently to reduce childhood mortality.


Congenital abnormalities, Hypoplasia, Respiratory tract infections

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Kisku KH, Panigrahi MK, Sudhakar R. Agenesis of lung-a report of two cases. Lung India: official organ of Indian Chest Society. 2008;25(1):28.

Nandan D, Bhatt GC, Dewan V, Pongener I. Complete right lung agenesis with dextrocardia: an unusual cause of respiratory distress. Journal of clinical imaging science. 2012;2.

Oymada A, Gasul BM, Holinger PM. Agenesis of the lung. Am J Dis Child. 1953;85(2):182-7.

Malcon MC, Malcon CM, Cavada MN, Caruso PE, Real LF. Agenesia pulmonar unilateral. Jornal Brasileiro de Pneumologia. 2012;38:526-9.

Sadiqi J, Hamidi H. CT features of lung agenesis–a case series (6 cases). BMC medical imaging. 2018;18(1):1-4.

Bayarogullari H, Arica V. Congenital Agenesis of the Left Lung: A Rare Case. Journal of Clinical Imaging Science. 2011;1(1):47.

Rahman M. A Case Report of Right Lung Agenesis With Klippel-Feil Syndrome. Chest. 2016;149(4):243.

Knowles S, Thomas RM, Lindenbaum RH, Keeling JW, Winter RM. Pulmonary agenesis as part of the VACTERL sequence. Archives of disease in childhood. 1988;63(7):723-6.

Khurram MS, Rao SP, Vamshipriya A. Pulmonary agenesis: a case report with review of literature. Qatar medical journal. 2014;2013(2):14.

Agrawal Y, Patri S, Kalavakunta JK. Right lung agenesis with tracheal stenosis due to complete tracheal rings and Postpneumonectomy like syndrome treated with tissue expander placement. Case reports in pulmonology. 2016.