Clinical profile of patients with acute pancreatitis

Authors

  • Prasad H. L. Department of Surgery, Mysore Medical College and Research Centre, Mysore
  • T. R. Nagarjuna Department of Surgery, Mysore Medical College and Research Centre, Mysore

DOI:

https://doi.org/10.18203/2320-6012.ijrms20161991

Keywords:

Acute pancreatitis, Alcoholism induced pancreatitis, Traumatic pancreatitis, Biliary etiology

Abstract

Background: The observation on acute pancreatitis showed that the ultimate severity is determined by events that occur during the early stages of pancreatitis has prompted several groups of investigators to undertake studies designed to determine which clinical, chemical, or radiologic parameters might be used to identify those patients destined to experience a severe illness. Therefore the present study is designed to evaluate the clinical profile of patients suffering from acute pancreatitic patients.

Methods: The study population consisted of 40 cases of acute pancreatitis that fulfilled the diagnostic criteria. Data collection on admission included age, sex, address and clinical presentation with respect to pain vomiting, gallstones trauma and drugs was noted. History of precious episodes and co- morbidities was noted. Chi-square tests were employed to find out the difference between groups of frequencies obtained for the specific statements. A P value of less than 0.05 was considered statistically significant.

Results: Out of 40 patients, Males were (55%) and (45%) were females. Majority of patients were belonging to the age group of 41-60 (42.5%) with a median age of 37 yrs. Most common etiology for acute pancreatitis was biliary (55%) followed by alcoholism (32.5%), hyperlipidaemia (2.5%) and traumatic (2.5%) pancreatitis was found in one patient each and where no cause was found was labelled as idiopathic (7.5%). Biliary pancreatitis was the cause of acute pancreatitis in Females 88.3%. In males, alcoholism induced pancreatitis (50%) was most common, second commonest was biliary etiology.

Conclusions: The most common etiology for acute pancreatitis was biliary followed by alcoholism and traumatic pancreatitis.  In Males, alcoholism induced pancreatitis was most common, second commonest was biliary etiology.

 

References

Fagenholz PJ, Castillo CF, Harris NS. Increasing United States hospital admissions for acute pancreatitis, 1988-2003. Ann Epidermiol. 2007;17:491-7.

Tenner S. Practice guidelines in acute pancreatitis. The American Journal of Gastroenterology. 2013;8:1400-15.

Baron TH, Morgan DE. Current concepts: Acute Necrrotizing Pancreatitis. N Engl J Med. 1999;18:1412-7.

Steinberg W, Tenner S. Acute pancreatitis. N Engl J Med. 1994;330:17:1198-210.

Chávez RM. History of the pancreas and the evolution of concepts and classification of pancreatitis. Rev Gastroenterol Peru. 2002;22(3):243-47.

Busnardo AC, DiDio LJ, Tidrick RT, Thomford NR. History of the pancreas. AMJ Surg. 1983;146(5):539-50.

Elrnan R. Arneson N. Graham E: Value of blood amylase estimation in the diagnosis of pancreatic disease: A clinical study Arch Surg. 1929;19:943-67.

Glenn F, Frey C. Re-evaluation of the treatment of pancreatitis associated with biliary tract disease. Ann Surg. 1964;160:723-36.

Ranson JH, Rifkmd KM, Roses DF. Prognostic signs and the role of operative management in acute pancreatitis. Surg Gvnecol Obstet. 1974;139(1):69-81.

Acosta JM, Ledesma CL. Gallstone migration as a cause of acute pancreatitis. N Engl J Med. 1974;290(9):484-7.

Werner J, Hartwig W, Uhl W, Müller C, Büchler MW. Useful markers for predicting severity and monitoring progression of acute pancreatitis. Pancreatology. 2003:3(2):115-27.

Michael L. APACHE-II scores for assessment and monitoring of acute pancreatitis The Lancet. 1989;334(8656):201-5.

Kandasami P, Harunarashid H, Kaur H. Acute Pancreatitis in a Multi-Ethnic Population Singapore Med J. 2002;43(6):284-88.

De Waele JJ, Hoste EA, Malbrain ML. Decompressive laparotomy for abdominal compartment syndrome – a critical analysis. Crit Care. 2006;10:51-5.

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Published

2017-01-03

How to Cite

H. L., P., & Nagarjuna, T. R. (2017). Clinical profile of patients with acute pancreatitis. International Journal of Research in Medical Sciences, 4(7), 2994–2997. https://doi.org/10.18203/2320-6012.ijrms20161991

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Section

Original Research Articles