Management of dermatoses with topical clobetasol propionate 0.025%


  • Maragondanahalli G. Gopala Department of Dermatology, Sree Venkateshwara Skin Clinic, Bangalore, Karnataka, India
  • Sidramappa R. Warad Department of Dermatology, Best Skin Clinic, Bijapur, Karnataka, India
  • Manas R. Puhan Department of Dermatology, Niki Skin Care, Cuttack, Odisha, India
  • Saurabh Agrawal Department of Dermatology, Saurabh Agrawal Clinic, Bikaner, Rajasthan, India
  • Sanjay J. Parbhani Department of Dermatology, Jogad Skin and Laser Center, Parbhani, Maharashtra, India
  • Kavita Mehendiratta Department of Dermatology, Dr. Kavita Skin Clinic, Faridabad, Haryana, India
  • Mahaveer P. Gupta Department of Dermatology, Medical Center, Jaipur, Rajasthan, India
  • Farhana T. Taj Department of Dermatology, KLE Deemed University, JNMC Campus, Belagavi, Karnataka, India
  • Vamja Chirag Department of Dermatology, Kalarav Hospital, Amreli, Gujarat, India
  • Satish D. A. Department of Dermatology, Skin Cosmetic and ENT Care Center, Bengaluru, Karnataka, India



Clobetasol propionate 0.025%, Topical corticosteroid, Plaque psoriasis, Psoriasis


The development of topical corticosteroids (TC) has enabled effective treatment of many dermatoses. The main therapeutic activity of topical corticosteroids is their nonspecific anti-inflammatory effect that primarily seems to be a result of their action on the chemical mediators of inflammation. Topical corticosteroids have also been shown to be antimitotic. Corticosteroids also play a vital role in cellular signaling, immune function and protein regulation. Clobetasol propionate (CP) 0.025% is a prescription corticosteroid medicine, used to treat moderate to severe plaque psoriasis in patients 18 years of age and older. It is a class I specialized cream formulation, that is free of propylene glycol, short-chain alcohols (e.g. ethanol), and sorbitan sesquioleate, a sorbitol-based emulsifier which is a common contact allergen used in many topical corticosteroid formulations. This case series discusses about management of different dermatoses using ImpoyzTM (clobetasol propionate) cream 0.025%.


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Del Rosso JQ. Topical corticosteroid therapy for psoriasis—a review of clobetasol propionate 0.025% cream and the clinical relevance of penetration modification. J Clin Aesthet Dermatol. 2020;13(2):22-9.

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Impoyz TM (clobetasol propionate) Cream. Available at: Accessed on 10 December 2021.




How to Cite

Gopala, M. G., Warad, S. R., Puhan, M. R., Agrawal, S., Parbhani, S. J., Mehendiratta, K., Gupta, M. P., Taj, F. T., Chirag, V., & A., S. D. (2022). Management of dermatoses with topical clobetasol propionate 0.025%. International Journal of Research in Medical Sciences, 10(3), 717–722.



Case Series