Presentation antineutrophil cytoplasmic autoantibody negative-associated granulomatosis with polyangiitis with pyuria

Can Huzmeli; Ferhan Candan; Recep İsmail Akın; Mansur Kayataş

doi:10.18203/2320-6012.ijrms20162000

Authors

Can Huzmeli Department of Nephrology, Cumhuriyet University, Sivas
Ferhan Candan Department of Nephrology, Cumhuriyet University, Sivas
Recep İsmail Akın Department of Radiology, Cumhuriyet University, Sivas
Mansur Kayataş Department of Nephrology, Cumhuriyet University, Sivas

DOI:

https://doi.org/10.18203/2320-6012.ijrms20162000

Keywords:

Pyuria, Hemoptysis, Granulomatous polyangiitis

Abstract

Pulmonary renal syndrome is a rare but serious complication of systemic vasculitis. The majority the cases are antineutrophil cytoplasmic autoantibody (ANCA)-associated vasculitis. In this case, a 58 years old female case having aworsening clinical picture of probable urinary infection and acute renal failure was presented. By means of proteinuria, pyuria, hematuria and unexplained acute renal failure, we review the relevant literature on pulmonary renal syndrome associated with granulomatosis with polyangiitis (GPA) with negative serum ANCA serology. This report demonstrates the difficulty of diagnosing granulomatosis with polyangiitis (GPA) until renal biopsy was done while initial diagnostic serological negative ANCA testing.

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