Plasmacytoma of clavicle bone: a case report

Authors

  • Anurag M. Agrawal Department of Surgery, GCS Medical College, Ahmedabad, Gujarat, India
  • Vidhyasagar V. Sharma Department of Surgery, GCS Medical College, Ahmedabad, Gujarat, India
  • Amruthavarshini S. Halughodu Department of Surgery, GCS Medical College, Ahmedabad, Gujarat, India

DOI:

https://doi.org/10.18203/2320-6012.ijrms20221195

Keywords:

Plasmacytoma, Multiple myeloma, Adjuvant chemoradiotherapy

Abstract

Plasmacytoma refers to a malignant tumor composed of plasma cells, which grows within soft tissue or axial skeleton. These are identical to those in plasma cell myeloma, which appears as a solitary lytic lesion on radiological examination. Primary bone tumor of clavicle are uncommon and likely to be malignant. Systemic issues in multiple myeloma are absent in plasmacytoma which makes it a formidable diagnostic challenge. Authors report a case of sixty-two years old female with progressive swelling around medial end of right clavicle associated with pain and restriction in arm movements. X-ray revealed lytic lesion in medial one-third of clavicle. FNAB revealed small to large plasmacytoid cells. CT Angiography revealed ill-defined heterogenous soft tissue density lesion. Since the mass was near the vascular structure, adjuvant chemoradiotherapy was given. Solitary plasmacytoma of bone (SPB) of medial end of clavicle is rare. Surgery is the mainstay treatment but in inoperable cases, adjuvant therapy may be considered. SPB of clavicle is a unique surgical entity with diagnostic and management challenges.

 

References

Jaffe ES, Harris NL, Stein H, Vardiman JW. World Health Organization Classification of Tumors: Pathology and Genetics, Tumors of Haematopoietic and Lymphoid Tissue. Ann Oncol. 1999;213:490-1.

Soutar R, Lucraft H, Jackson G, Reece A, Bird J. Guidelines on the diagnosis and management of solitary plasmacytoma of bone and solitary extramedullary plasmacytoma. Br J Haematol. 2004;124(6):717-26.

Smith J, Yuppa F, Watson RC. Primary tumors and tumor-like lesions of the clavicle. Skeletal Radiol. 1988;17(4):235-46.

Carter PM, Rushman RW. Solitary plasmacytoma of the clavicle. Proc R Soc Med. 1974;67(11):1097-8.

Panagopoulos A, Megas P, Kaisidis A, Dimakopoulos P. Radiotherapy resistant solitary bone plasmacytoma of the clavicle. Eur J Trauma. 2006;32:190-93.

Shih LY, Dunn P, Leung WM, Chen WJ, Wang PN. Localised plasmacytomas in Taiwan: comparison between extramedullary plasmacytoma and solitary plasmacytoma of bone. Br J Cancer. 1995;71(1):128-33.

Reed V, Shah J, Medeiros LJ, Ha CS, Mazloom A. Solitary plasmacytomas: outcome and prognostic factors after definitive radiation therapy. Cancer. 2011;117(19):4468-74.

Meis JM, Butler JJ, Osborne BM, Ordóñez NG. Solitary plasmacytomas of the bone and extramedullary plasmacytomas. A clinicopathologic and immunohistochemical study. Cancer. 1987;59(8):1475-85.

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Published

2022-04-26

How to Cite

Agrawal, A. M., Sharma, V. V., & Halughodu, A. S. (2022). Plasmacytoma of clavicle bone: a case report. International Journal of Research in Medical Sciences, 10(5), 1196–1198. https://doi.org/10.18203/2320-6012.ijrms20221195

Issue

Section

Case Reports