Current therapeutic status of corticosteroid in human immunodeficiency virus patients with tuberculous meningitis

Authors

  • Ajit Kumar Mishra Department of Pharmacology and Therapeutics, KGMU, Lucknow, India
  • Shoebul Haque Department of Pharmacology and Therapeutics, KGMU, Lucknow, India
  • A. K. Sachan Department of Pharmacology and Therapeutics, KGMU, Lucknow, India
  • R. K. Dixit Department of Pharmacology and Therapeutics, KGMU, Lucknow, India

DOI:

https://doi.org/10.18203/2320-6012.ijrms20222548

Keywords:

Corticosteroid, HIV, TBM

Abstract

Human immunodeficiency virus (HIV) poses risk for severe manifestation of TB. These may be in the form of pulmonary or extra pulmonary. According to the level of immunosupression there is risk of developing tuberculous meningitis (TBM). HIV alters pathogenesis, clinical features and prognosis throwing diagnostic and therapeutic challenges.

 

References

Vinnard C, MacGregor RR. Tuberculous meningitis in HIV-infected individuals. Curr HIV/AIDS Rep. 2009;6(3):139-45.

Bell LCK, Breen R, Miller RF, Noursadeghi M, Lipman M. Paradoxical reactions and immune reconstitution inflammatory syndrome in tuberculosis. Int J Infect Dis. 2015;32:39-45.

Harries AD, Hargreaves NJ, Kemp J, Jindani A, Enarson DA, Maher D, et al. Deaths from tuberculosis in sub-Saharan African countries with a high prevalence of HIV-1. Lancet. 2001;357(9267):1519-23.

Heemskerk AD, Bang ND, Mai NTH, Chau TTH, Phu NH, Loc PP, et al. Intensified antituberculosis therapy in adults with tuberculous meningitis. N Engl J Med. 2016;374(2):124-34.

Prasad K, Singh MB, Ryan H. Corticosteroids for managing tuberculous meningitis. Cochrane Database Syst Rev. 2016;2016(4).

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Published

2022-09-27

How to Cite

Mishra, A. K., Haque, S., Sachan, A. K., & Dixit, R. K. (2022). Current therapeutic status of corticosteroid in human immunodeficiency virus patients with tuberculous meningitis. International Journal of Research in Medical Sciences, 10(10), 2346–2347. https://doi.org/10.18203/2320-6012.ijrms20222548

Issue

Section

Letter to the Editor