Autopsy: a value to primordial and primary prevention for lung diseases
DOI:
https://doi.org/10.18203/2320-6012.ijrms20222841Keywords:
Autopsy, Lung, Pneumonia, TuberculosisAbstract
Background: Lung disorders spectrums include congestion, oedema, various inflammatory lesions, chronic obstructive pulmonary diseases and neoplastic lesions. The clinical and radiological findings in respiratory diseases are nonspecific and therefore a histopathological study is essential. Autopsies are necessary to establish cause of death of the person with help of antemortem history and investigations to rule out lung lesions. Aims and objectives were to identify the histopathological spectrum of lung disease and frequency of various lung pathologies in respect to age and sex.
Methods: The retrospective study of 285 lung autopsy specimens received were fixed and processed. Routine paraffin sectioning was done followed by hematoxylene and eosin (H and E) staining. Relevant clinical and postmortem findings, gross and microscopic examination findings were recorded.
Results: Most common lung pathology found was Edema and congestion in 149 cases (52.2%), pneumonia in 87 cases (30.5%) followed by tuberculosis in 33 cases (11.5%). Out of total 285 cases, 222 (77.9%) were males and 63 cases (22.2%) were females. The male to female ratio was 3.5:1. Maximum numbers of cases, in age group of 31-45 years were 108 cases (37.89%) followed by in age group 46-60 years were 90 cases (31.57%) followed by age group of 16-30 years 15.8%.
Conclusions: Advances in diagnostic technology have not reduced the value of autopsy for the study and evaluation of the disease process. It has become crucial for adopting correct prophylactic actions for primordial and primary prevention of pulmonary dysfunctions.
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References
Selvambigai G, Amudhavalli S, Deepak Chakravarthi CD, Ravi S. Histopathological study of lung in autopsy cases: a prospective study. Int J Res Med Sci. 2016;4:4816-9.
Patel CB, Patel K, Bhagat VM, Shah P. Pattern of histopathological lesions in lung autopsy. Int J Res Med Sci. 2018;6(1):279-83.
Bal MS, Sethi PS, Suri AK, Bodal VK, Kaur G. Histopathological pattern in lung autopsies. J Punjab Acad Forens Med Toxicol. 2008;8(2):29-31.
Hall JE. Guyton and Hall Textbook of Medical Physiology. 13th edn. Elsevier: Saunders; 2015.
Kumar V, Abbas A, Aster J. Pathologic basis of disease. 1st edn. Vol 2. Elsevier India; 2014.
Kasper D, Fauci A, Hauser S, Longo D, Jameson J, Loscalzo J, eds. Harrison’s principles of internal medicine, 19th edn. Vol 2. Mc Graw Hill: Indian edition; 2015.
Udayashankar SK, Shashikala P, Kavita GU, Deepti P. Histomorphogical pattern of lung in medicolegal autopsies. Int J Sci Res. 2015;4(7):1937-9.
Tahir TM, Rehman F, Anwar S, Kamal F. Patterns of pulmonary morphological lesions seen at autopsy. Biomedica. 2013;29:64-8.
Pathak A, Mangal HM. Histopathology examination in medico-legal autopsy pros and cons. J Indian Acad Forens Med. 2008;32(2):128-31.
Shweta, Deepti M, Vidhu M, Angmo P. Histopathological pattern in lung autopsy in Government medical college Jammu. J Evol Med Dent Sci. 2015;4(91):15694-96.
Chauhan G, Agrawal M, Thakkar N, Parghi B. Spectrum of histopathological lesions in lung autopsy. J Res Med Den Sci. 2015;3(2):109-12.
Ghosal R, Kloer P, Lewis KE. A review of novel biological tools used in screening for the early detection of lung cancer. Postgrad Med J. 2009;85:358-63.
Amin NS, Shah PY, Patel RG, Khant VS, Prajapati SG. Histopathological alterations in lung tissue received as autopsy specimens- a study of 410 cases. Int J Med Sci Public Health. 2017;6(2):327-30.
Kurawar RR, Vasaikar MS. Spectrum of histomorphological changes in lungs at autopsy: a 5 year study. Ann Pathol Lab Med. 2017;4(1):106-12.
Garg P, Sharma A, Kundal RK. Spectrum of pulmonary histopathological lesions: a study of 100 autopsy cases. J Med Sci Clin Res. 2017;5:3.
Fang F, Lin FR, Li HZ. Clinicopathologic analysis of organizing pneumonia in elderly autopsies. Zhonghua Bing Li Xue Za Zhi Chinese J Pathol. 2004;33(2):113-6.
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