Drug induced methemoglobinemia: a case report


  • Shrushti Y. Dalal Department of Medicine, GMERS Medical College and Hospital, Vadodara, Gujarat, India
  • Prateek V. Dalal Department of Cardiology, Peconic Bay Medical Center, Northwell Health, New York, United States of America




Dapsone, Methemoglobin, Central cyanosis


Methemoglobinemia (MetHb) is an uncommon cause of central cyanosis and hence, not frequently considered in the differential diagnosis. Methemoglobin is an abnormal form of hemoglobin which is produced physiologically due to autooxidation. If this process of autooxidation is disturbed, either due to genetic or due to exogeneous drugs/toxins, its level rises in blood leading to tissue hypoxia. It causes central cyanosis when its level exceeds 3%. We present the case of a 19-year-old male patient who was diagnosed with methemoglobinemia due to the use of dapsone for acne vulgaris. Our case emphasizes the significance of detailed history taking, knowledge and high index of suspicion for drug-induced methemoglobinemia.



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How to Cite

Dalal, S. Y., & Dalal, P. V. (2022). Drug induced methemoglobinemia: a case report. International Journal of Research in Medical Sciences, 10(11), 2684–2685. https://doi.org/10.18203/2320-6012.ijrms20222882



Case Reports