Psychosocial experience of mothers of children with sickle cell disease in Antananarivo and Toamasina, Madagascar

Hanitriniaina S. C. Samena; Rina J. Rasamoelison; Safidisoa N. Razanamanana; Annick L. Robinson

doi:10.18203/2320-6012.ijrms20222832

Authors

Hanitriniaina S. C. Samena Department of Pediatrics, Tsaralalana Mother-Child University Hospital, Antananarivo, Madagascar http://orcid.org/0000-0001-8517-6926
Rina J. Rasamoelison Department of Neonatalogy, Befelatanana Maternity, Antananarivo, Madagascar http://orcid.org/0000-0003-4099-0312
Safidisoa N. Razanamanana Department of Pediatrics, Itaosy District Reference Hospital Center, Antananarivo, Madagascar
Annick L. Robinson Department of Pediatrics, Tsaralalana Mother-Child University Hospital, Antananarivo, Madagascar Faculty of Medicine, Antananarivo, Madagascar

DOI:

https://doi.org/10.18203/2320-6012.ijrms20222832

Keywords:

Anxiety, Children, Depression, Mothers, Sickle cell disease

Abstract

Background: Sickle cell disease in children can disrupt life of their mothers who are at the forefront of care. The objectives of this study were to describe the psychosocial experience of these mothers, to identify factors associated to maternal anxiety and depressive disorders.

Methods: A cross-sectional study was conducted from December 2017 to February 2018 with mothers of children with sickle cell disease under the age of 15 in Antananarivo and Toamasina. The abbreviated Beck and Hamilton scales were used to assess respectively depression and anxiety.

Results: Of 134 mothers surveyed, 61.2% had depression and 35.8% had anxiety. Depression significantly affected mothers with more than one child with sickle cell disease (aOR=4.31, CI- 1.12-16.58) and mothers of children hospitalized at least three times per year for vaso-occlusive crisis (aOR=13.55, CI- 1.56-117.5). Anxiety was associated with blood transfusion more than three times (aOR=9.06, CI- 2.05-40.00). Pity (74.6%) and fear of death (55.2%) were the main feelings reported. Negative occupational repercussions were reported by 48.5% of mothers, marital conflict by 15.6%, financial difficulties by 43.3%.

Conclusions: A global approach focused on the child and his family would be optimal for success in the management of pediatric sickle cell disease.

Metrics

Metrics Loading ...

References

World Health Organization. Thalassaemia and other haemoglobinopathies: Report by the Secretariat. Geneva, Switzerland: WHO; 2006. Available from: https://apps.who.int/gb/archive/pdf_files/EB118/B118_5-en.pdf. Accessed on 16 October 2017.

Mulumba LL, Wilson L. Sickle cell disease among children in Africa: An integrative literature review and global recommendations. Int J Afr Nurs Sci 2015;3:56‑64.

Ministry of Public Health. National sickle cell disease control program in Madagascar. Madagascar: MSANP; 2011.

Brown RT, Kaslow NJ, Doepke K, Buchanan I, Eckman J, Baldwin K, et al. Psychosocial and family functioning in children with sickle cell syndrome and their mothers. J Am Acad Child Adolesc Psychiatr. 1993;32(3):545‑53.

Alsaleh M, Lebreuilly R. Validation of the French translation of a short questionnaire Beck Depression (BDI-FS-Fr). Ann Med Psychol. 2017;175(7):608‑16.

Maier W, Buller R, Philipp M, Heuser I. The Hamilton anxiety scale: reliability, validity and sensitivity to change in anxiety and depressive disorders. J Affect Disord. 1988;14(1):61‑8.

Assimadi JK, Gbadoé AD, Nyadanu M. The effects of sickle cell disease on families in Togo. Arch Pediatr. 2000;7(6):615-20.

Clarke DM, Currie KC. Depression, anxiety and their relationship with chronic diseases: a review of the epidemiology, risk and treatment evidence. Med J Aust. 2009;190(7):54-60.

Van Oers HA, Haverman L, Limperg PF, van Dijk-Lokkart EM, Maurice-Stam H, Grootenhuis MA. Anxiety and depression in mothers and fathers of a chronically ill child. Matern Child Health J. 2014;18(8):1993-2002.

Nika ER, Mabiala Babela JR, Moyen E, Kambourou J, Lombet L, Mouanga Mpolo P, et al. Psychosocial issues of mothers whose children have sickle cell disease. Arch Pediatr. 2016;23(11):1135-40.

Brown BJ, Okereke JO, Lagunju IA, Orimadegun AE, Ohaeri JU, Akinyinka OO. Burden of health-care of carers of children with sickle cell disease in Nigeria. Health Soc Care Community. 2010;18(3):289-95.

Macedo EC, da Silva LR, Paiva MS, Ramos MNP. Burden and quality of life of mothers of children and adolescents with chronic illnesses: an integrative review. Rev Lat Am Enfermagem. 2015;23(4):769-77.

Luboya E, Tshilonda JCB, Ekila MB, Aloni MN. Psychosocial repercussions of sickle cell disease on parents of children living in Kinshasa, Democratic Republic of Congo: a qualitative study. Pan Afr Med J. 2014;19:5.

Olatunya OS, Ogundare EO, Fadare JO, Oluwayemi IO, Agaja OT, Adeyefa BS, et al. The financial burden of sickle cell disease on households in Ekiti, Southwest Nigeria. Clin Outcomes Res. 2015;7:545-53.

Rahimy MC, Gangbo A, Ahouignan G, Adjou R, Deguenon C, Goussanou S, et al. Effect of a comprehensive clinical care program on disease course in severely ill children with sickle cell anemia in a sub-Saharan African setting. Blood. 2003;102(3):834-8.

Daher Habeeb A, Alhussain B, Hassan M, Ahmed B. Psychosocial impact of sickle cell disease on families in Basra, Southern Iraq; an experience of caregivers. Int J Med Pharm Sci. 2015;5:41-52.

Adegoke SA, Kuteyi EA. Psychosocial burden of sickle cell disease on the family, Nigeria. Afr J Prim Health Care Fam Med. 2012;4(1):380.

Palermo TM, Riley CA, Mitchell BA. Daily functioning and quality of life in children with sickle cell disease pain: Relationship with family and neighborhood socioeconomic distress. J Pain Off J Am Pain Soc. 2008;9(9):833‑40.

Graumlich SE, Powers SW, Byars KC, Schwarber LA, Mitchell MJ, Kalinyak KA. Multidimensional assessment of pain in pediatric sickle cell disease. J Pediatr Psychol. 2001;26(4):203‑14.

Petermann R, Pêchard M, Gesbert C, Assez N. Blood representations associated to chronic transfused patients: Symbolic interpretations and ethical perspectives. Transfus Clin Biol. 2016;3(23):157‑67.