Published: 2022-10-28

Giant leiomyosarcoma of the anterior abdominal wall: case report and review of the literature

Yankel Sanchez, Karla Altamirano, Manuel Garcia


Smooth muscle tumors are rare tumors with a low worldwide incidence, which is a diagnostic and therapeutic challenge for doctors, within these, leiomyosarcomas are tumors that occur more frequently in the uterus or abdominal cavity, however, another presentation called leiomyosarcomas peripheral which are subdivided into cutaneous or subcutaneous which tend to appear in the extremities of the lower limbs. The presentation of a clinical case of a patient of the eighth decade of life who presents a giant tumor of the ulcerative abdominal wall and hemorrhage that conditions anemia syndrome and hemorrhagic shock is made, for which an emergency surgical resection is performed. The treatment of leiomyosarcoma consists of surgical removal, however the margins are not clearly defined and regularly require a multidisciplinary team that includes an oncological surgeon and a plastic and reconstructive surgeon. In advanced cases and selected patients, medical treatment with chemotherapy can be granted.



Leiomyosarcoma, Surgery, Abdominal wall

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Ciurea ME, Georgescu CV, Radu CC, Georgescu CC, Stoica LE. Cutaneous leiomyosarcoma-Case report. J Med Life. 2014;7(2):270-3.

Llombart B, Serra-Guillén C, Requena C, Alsina M, Morgado-Carrasco D, Machado I et al. Leiomyosarcoma and dermal pleomorphic sarcoma: guidelines for diagnosis and treatment. Actas Dermo-syphilographic. 2019;110(1):4-11.

Sandhu N, Sauvageau AP, Groman A, Bogner PN. Cutaneous leiomyosarcoma: A SEER database analysis: A SEER database analysis. Dermatologic Surg. 2020:46(2):159-64.

Wen-Chieh L, Yu-Chen W, Hsu M. Cutaneous Leiomyosarcoma. Ann Plastic Surg. 2017;78(3):S47-51.

Hmida L, Letaief F, Doghri R, Meddeb K, Mahjoubi K, Mokrani A Et al. Cutaneous leiomyosarcoma on the trunk: An unusual presentation with an aggressive course - Case report and review of literature. Pan Afr Med J. 2018;31:190.

Beck EM, Bauman TM, Rosman IS. A tale of two clones: Caldesmon staining in the differentiation of cutaneous spindle cell neoplasms. J Cutaneous Pathol. 2018;45(8):581-7.

Christopher JWMB, Jauszkiewicz J. Leiomiosarcoma cutáneo, Cirugía plástica y resconstructiva. 2022;109(3):964-7.

Deneve JL, Messina JL, Bui MM, Marzban SS, Letson GD, Cheong D et al. Cutaneous leiomyosarcoma: treatment and outcomes with a standardized margin of resection. Cancer Control. 2013;(4):307-12.

Aneiros-Fernandez J, Antonio Retamero J, Husein-Elahmed H, Ovalle F, Aneiros-Cachaza J. Primary cutaneous and subcutaneous leiomyosarcomas: evolution and prognostic factors. Eur J Dermatol. 2016;26(1):9-12.

Soares Queirós C, Filipe P, Soares de Almeida L. Cutaneous leiomyosarcoma: a 20-year retrospective study and review of the literature. An Bras Dermatol. 2021;(3):278-83.