Diagnostic accuracy of computed tomography scan in renal cell carcinoma
DOI:
https://doi.org/10.18203/2320-6012.ijrms20231598Keywords:
Tomography, Carcinoma, CT scan, Renal, AccuracyAbstract
Background: Renal cell carcinoma (RCC) is becoming more common over the world. At the same time, numerous European and North American countries have achieved lower death rates.
Methods: This cross-sectional observational study was conducted from July 2013 to June 2014 in the department of radiology and imaging of Dhaka Medical College Hospital. Clinically suspected 50 cases of renal cell carcinoma were included in this study. The study taken ethical clearance from the department and consent from the respondents. Statistical package for the social sciences (SPSS) software used for the analysis.
Results: The mean age of the patients was 50.08±13.04 years. Male to female ratio was 2.1. More than half of the cases had hypodense lesion while 28% patients had calcification in the lesion. Mild enhancement was found in 56% cases and 50% were heterogenous in nature. Both nodal involvement and metastasis were limited. Computed tomography (CT) scan had 97.73% sensitivity and 100% specificity in diagnosis RCC. The diagnostic accuracy, positive predicative value and negative predicative values were 98%, 100% and 85.7 respectively.
Conclusions: CT scan is a useful diagnostic modality in diagnosis of renal cell carcinoma.
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References
Ferlay JF. GLOBOCAN, 2000. Cancer incidence, mortality and prevalence worldwide, version 1.0. IARC cancer base. 2001.
Grainger RG, Allison DJ, Dixon AK, Adam A. Grainger Allison's diagnostic radiology, 5th edn, Elsevier Churchill Livingstone. 2008;2:819-65.
McCredie M. Bladder and kidney cancers. Cancer Surv. 1994;19:343-68.
Haaga JR, Lanzieri CF, Gilkeson RC. CT and MR imaging of the whole body, 4th edn, Mosby, Missouri. 2003;1:1537-63.
Gelb AB. Renal cell carcinoma: current prognostic factors. Cancer: Interdisciplinary Int J Am Cancer Soc. 1997;80(5):981-6.
Motzer RJ, Bander NH, Nanus DM. Renal-cell carcinoma. New Engl J Med. 1996;335(12):865-75.
Jayson M, Sanders H. Increased incidence of serendipitously discovered renal cell carcinoma. Urology. 1998;51(2):203-5.
Ljungberg B, Bensalah K, Canfield S, Dabestani S. EAU guidelines on renal cell carcinoma: 2014 update. Eur Urol. 2015;67(5):913-24.
Schachter LR, Cookson MS, Chang SS, Smith, Jr JA, et al. Second prize: frequency of benign renal cortical tumors and histologic subtypes based on size in a contemporary series: what to tell our patients. J Endourol. 2007;21(8):819-23.
Israel GM, Bosniak MA. Pitfalls in renal mass evaluation and how to avoid them. Radiographics. 2008;28(5):1325-38.
Coll DM, Smith RC. Update on radiological imaging of renal cell carcinoma. BJU Int. 2007;99(5b):1217-22.
Amendola MA, Bree RL, Pollack HM, Francis IR, et al. Small renal cell carcinomas: resolving a diagnostic dilemma. Radiology. 1988;166(3):637-41.
Khan AR, Anwar K, Fatima N, Khan SF. Comparison of CT scan and colour flow Doppler ultrasound in detecting venous tumour thrombous in renal cell carcinoma. J Ayub Med Coll Abbottabad. 2008;20(3):47-50.
Türkvatan A, Akdur PÖ, Altinel M, Ölçer T, Turhan N, et al. Preoperative staging of renal cell carcinoma with multidetector CT. Diagnost Intervent Radiol. 2009;15(1):22-30.
Jamis-Dow CA, Choyke PL, Jennings SB, Linehan WM. Small (≤3 cm) renal masses: detection with CT versus US and pathologic correlation. Radiology. 1996;198(3):785-8.
Andrew CN, Steven CC. Campbell's Urology 8th edition, Saunders, Philadelphia, London. 2002;4.
Sutton D. A Text book Radiology & Imaging, 7th edn, Churchill Livingstone & Imprint of Elsevier Ltd., London. 2003;2:885-954.
Biswas NP, Islam MS, Hossain MZ, Uddin MH. Evaluation of Renal Tumour by Ultrasound and CT Scan-A comparative analysis. Bangl J Urol. 2011;14(2):55-7.
Ruppert-Kohlmayr AJ, Uggowitzer M, Meissnitzer T, Ruppert G. Differentiation of renal clear cell carcinoma and renal papillary carcinoma using quantitative CT enhancement parameters. Am J Roentgenol. 2004;183(5):1387-91.
Divgi CR, Uzzo RG, Gatsonis C, Bartz R, Treutner S, Yu JQ, et al. Positron emission tomography/computed tomography identification of clear cell renal cell carcinoma: results from the REDECT trial. J Clin Oncol. 2013;31(2):187.
Liu Y, Kan Y, Zhang J, Li N, Wang Y. Characteristics of contrast-enhanced ultrasound for diagnosis of solid clear cell renal cell carcinomas ≤4 cm: A meta-analysis. Cancer Med. 2021;10(23):8288-99.
Tamai H, Takiguchi Y, Oka M, Shingaki N, Enomoto S, Shiraki T, et al. Contrast-enhanced ultrasonography in the diagnosis of solid renal tumors. J Ultrasound Med. 2005;24(12):1635-40.
Yuan XC, Wang Y, Zhou AY, Chen L. Comparison on contrast-enhanced ultrasonography and CT in diagnosing renal cell carcinoma. Chin J Med Imaging Technol. 2011;27(12):2502-5.
Kim JK, Kim TK, Ahn HJ, Kim CS, Kim KR, Cho KS. Differentiation of subtypes of renal cell carcinoma on helical CT scans. AJR Am J Roentgenol. 2002;178(6):1499-506.
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