Topical steroid induced Cushing’s syndrome-a rare entity

Authors

  • Manigandan Gopi Department of Medicine, PM Medical Centre, Walajapet, Tamil Nadu, India
  • M. S. Seshadri Department of Endocrinology and Metabolism, Thirumalai Mission Hospital, Ranipet, Tamil Nadu, India

DOI:

https://doi.org/10.18203/2320-6012.ijrms20223306

Keywords:

Topical steroid, Psoriasis, Cushings syndrome

Abstract

The topical steroid therapy is the commonest mode of treatment for Psoriasis. When the therapy is overused, it can cause unusual side effects like Cushing’s syndrome which is very rarely reported and we are reporting such a case. Treatment with maintenance dose of steroids is necessary based on basal cortisol levels to avert hypocortisolemic crisis in Cushing’s syndrome, however in some select asymptomatic cases maintenance dose of steroids can be withdrawn and only stress dose be given in spite of low basal serum cortisol. We managed such a case and it is reported because of its rarity in clinical practice. This can alert the clinicians to avoid prescribing steroids as maintenance dose for a long time in asymptomatic Cushing’s syndrome with low morning cortisol and thereby reducing the side effects of long-term steroids on them.

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Author Biography

Manigandan Gopi, Department of Medicine, PM Medical Centre, Walajapet, Tamil Nadu, India

Consultant Physician & Medical Director

References

Naldi L, Rzany B. Psoriasis (chronic plaque). BMJ Clin Evid. 2009;2009:1706.

Lynnette NK. The Diagnosis of Cushing’s Syndrome: An Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metabol. 2008;93(5):1526-40.

Hopkins RL, Leinung MC. Exogenous Cushing's syndrome and glucocorticoid withdrawal. Endocrinol Metab Clin North Am. 2005;34:371-84.

Birsen S. Iatrogenic Cushing’s Syndrome After Topical Steroid Therapy for Psoriasis. Indian J Dermatol. 2016;61(1):120.

Coondoo A, Phiske M, Verma S, Lahiri K. Side-effects of topical steroids: A long overdue revisit. Indian Dermatol Online J. 2014;5:416-25.

Krasner AS. Glucocorticoid-induced adrenal insufficiency. JAMA. 1999;282:671-6.

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Published

2022-12-30

How to Cite

Gopi, M., & Seshadri, M. S. (2022). Topical steroid induced Cushing’s syndrome-a rare entity. International Journal of Research in Medical Sciences, 11(1), 358–360. https://doi.org/10.18203/2320-6012.ijrms20223306

Issue

Section

Case Reports