The role of the initial modality in the investigation of thyroid lesions
DOI:
https://doi.org/10.18203/2320-6012.ijrms20230566Keywords:
Thyroidectomies, Pathologist, Thyroid nodules, Non-neoplastic, MalignancyAbstract
Background: Partial or complete thyroidectomies are frequently encountered via the working towards pathologist and the opportunity of neoplastic disease is of principal problem in patients with thyroid nodules. Pathological comparison of these specimens ranged from non-neoplastic lesion to exceedingly aggressive malignancy. The aim of this study is to assess the role of the initial modality in the investigation of thyroid lesions.
Methods: This is an observational study. The study used to be carried out in the admitted patient’s department of histopathology, National institute of ear, nose and throat, Dhaka. Bangladesh. In Bangladesh for the duration of the period from June 2021 to May 2022.
Results: This study shows that according to 301 patients where, most of the patients in initial modality in the investigation of thyroid lesions 95 (31.56%) were 40 to 49 years and the minimum sex distribution of study 105 (34.88%) belongs to males. Non-neoplastic of goiter were 194 (64.45%), benign cyst was 43 (14.29%), DeQuervains (Subacute) thyroiditis 11 (3.65%), Lymphocytic thyroiditis were 8 (2.65%) and hashimoto thyroiditis were 3 (1.0%). And acfemalesg to neoplastic of papillary carcinoma were 30 (9.97%), Follicular neoplasm were 9 (2.99%) and Anaplastic carcinoma were 3 (1.0%).
Conclusions: Thyroid lesions are more common in female. The majority of the thyroid nodules are either non-neoplastic or benign neoplasm. Thyroid lesions present a dependable analysis and is an incredible first line technique for investigating the nature of lesion.
Metrics
References
Kochupillai N. Clinical endocrinology in India. Curr Sci. 2000;79(8):1061-7.
Bayliss RIS, Tunbridge WMG. Thyroid disease: the facts. USA: Oxford University Press; 1998
Mackenzie EJ, Mortimer RH. Thyroid nodules and thyroid cancer. Med J Aus. 2004;180(5):242-7.
Orlov D. Thyroid nodules. Am Fam Physician. 2000; 67(3):559-66.
Elahi S, Manzoor-ul-Hassan A, Syed Z, Nazeer L, Nagra S, Hyder S. A study of goiter among female adolescents referred to centre for nuclear medicine, Lahore. Pak J Med Sci. 2005;21(1):56-62.
Hussain N, Anwar M, Nadia N, Ali Z. Pattern of surgically treated thyroid diseases in Karachi. Biomedica. 2005;21(1):18-20.
Darwish AH, Al Sindi KA, El Kafsi J, Bacantab M. Pattern of thyroid diseases-a histopathological study. Bahrain Med Bull. 2006;28(4):1-6.
Sushel C, Khanzada TW, Zulfikar I. Histopathological pattern of diagnoses in patients undergoing thyroid operations. Rawal Med J. 2009;34(1):1-7.
Maitra A, Abbas AK. Endocrine system. In: Robbins and Cotran pathologic basis of disease. USA: Elsevier; 2002.
Faquin WC. The thyroid gland: recurring problems in histologic and cytologic evaluation. Arch Pathol Lab Med. 2008;132(4):622-32.
Rossi ED, Raffaelli M, Mule' A, Miraglia A, Lombardi CP, Vecchio FM, Fadda G. Simultaneous immunohistochemical expression of HBME-1 and galectin-3 differentiates papillary carcinomas from hyperfunctioning lesions of the thyroid. Histopathology. 2006;48(7):795-800.
Wang C, Crapo LM. The epidemiology of thyroid disease and implications for screening. Endocrinol Metab Clin North Am. 1997;26(1):189-218.
Morganti S, Ceda GP, Saccani M, Milli B, Ugolotti D, Prampolini R, Maggio M, Valenti G, Ceresini G. Thyroid disease in the elderly: sex-related differences in clinical expression. J Endocrinol Invest. 2005; 28(11):101-4.
Al-Hureibi KA, Abdulmughni YA, Al-Hureibi MA, Al-Hureibi YA, Ghafoor MA. The epidemiology, pathology, and management of goitre in Yemen. Ann Saudi Med. 2004;24(2):119-23.
Cole WH, Watne AL. Incidence of carcinoma of the thyroid in nodular goiter. In: surgical oncology. New York: John Wiley & Sons, Inc; 2002:7(2);61-3.
Koh KB, Chang KW. Carcinoma in multinodular goitre. Br J Surg. 1992;79(3):266-7.
Mathai V, Idikula J, Fenn AS, Nair A. Do long-standing nodular goitres result in malignancies? Aust N Z J Surg. 1994;64(3):180-2.
Gandolfi PP, Frisina A, Raffa M, Renda F, Rocchetti O, Ruggeri C, Tombolini A. The incidence of thyroid carcinoma in multinodular goiter: retrospective analysis. Acta Biomed. 2004;75(2):114-7.
Sachmechi I, Miller E, Varatharajah R, Chernys A, Carroll Z, Kissin E, Rosner F. Thyroid carcinoma in single cold nodules and in cold nodules of multinodular goiters. Endocr Pract. 2000;6(1):5-7.
Gandolfi PP, Frisina A, Raffa M, Renda F, Rocchetti O, Ruggeri C, Tombolini A. The incidence of thyroid carcinoma in multinodular goiter: retrospective analysis. Acta Biomed. 2004;75(2):114-7.
Saeed MI, Hassan AA, Butt ME, Baniyaseen KA, Siddiqui MI, Bogari NM, Al-Allaf FA, Taher MM. Pattern of Thyroid Lesions in Western Region of Saudi Arabia: A Retrospective Analysis and Literature Review. J Clin Med Res. 2018;10(2):106-16.
Cipolla C, Sandonato L, Graceffa G, Fricano S, Torcivia A, Vieni S, Latteri S, Latteri MA. Hashimoto thyroiditis coexistent with papillary thyroid carcinoma. Am Surg. 2005;71(10):874-8.
Dailey ME, Lindsay S, Skahen R. Relation of thyroid neoplasms to Hashimoto disease of the thyroid gland. AMA Arch Surg. 1955;70(2):291-7.
Larson SD, Jackson LN, Riall TS, Uchida T, Thomas RP, Qiu S, Evers BM. Increased incidence of well-differentiated thyroid cancer associated with Hashimoto thyroiditis and the role of the PI3k/Akt pathway. J Am Coll Surg. 2007;204(5):764-73.
Sulimani RA. Thyroid cancer coexisting with Hashimoto's thyroiditis at King Khalid University Hospital, Saudi Arabia. East Afr Med J. 1996;73(11): 767-8.
Singh B, Shaha AR, Trivedi H, Carew JF, Poluri A, Shah JP. Coexistent Hashimoto's thyroiditis with papillary thyroid carcinoma: impact on presentation, management, and outcome. Surgery. 1999;126(6): 1070-7.
Sheils O, Smyth P, Finn S, Sweeney EC. RET/PTC rearrangements in Hashimoto's thyroiditis. Int J Surg Pathol. 2002;10(2):167-8.
Downloads
Published
How to Cite
Issue
Section
