Lens thickness and associated ocular biometric factors among cataract patients in tertiary hospital
DOI:
https://doi.org/10.18203/2320-6012.ijrms20230307Keywords:
ACD, AL, Biometry, Intraocular lens, LTAbstract
Background: A significant factor in determining intraocular lens power is the biometry assessment of cataract patients prior to surgery. To evaluate the distribution of lens thickness (LT) and its associations with other ocular biometric factors among cataract patients.
Methods: Total 978 eyes from cataract patients were retrospectively included. Ocular biometric factors including k1, k2, LT, central corneal thickness (CCT), anterior chamber depth (ACD), white-to-white (WTW) distance, and axial length (AL) were collected based on the medical records. The associations between LT and general or ocular factors were assessed. We analyzed the data using descriptive analysis and correlated each variable using the Spearman’s Rho analysis.
Results: The mean age was 62.5±15.70 years and 55.11% were females. Mean LT was 4.35±0.41 mm. The LT was greater in older patients. LT positively correlated with AL, WTW and CCT, while negatively correlated with ACD.
Conclusions: LT is an important biometric parameter that should be considered, along with other biometric parameters, in determining effective lens position in patients undergoing cataract surgery. ACD is predominantly influenced by LT than the AL.
References
Perkins ES. Lens thickness in early cataract. Br J Ophthalmol. 1988;72(5):348-53.
Meng J, Wei L, He W, Qi J, Lu Y, Zhu X. Lens thickness and associated ocular biometric factors among cataract patients in Shanghai. Eye Vis (Lond). 2021;8(1):22.
Rabsilber T, Jepsen C, Auffarth G, Holzer M. Intraocular lens power calculation: Clinical comparison of two ocular biometry devices. J Cataract Refract Surg. 2010;36:230-4.
Saka N, Ohno-Matsui K, Shimada N, Sueyoshi S, Nagaoka N, Hayashi W et al. Long-term changes in axial length in adult eyes with pathologic myopia. Am J Ophthalmol. 2010;150:562-8.
Ruiz-Moreno J, Montero J, de la Vega C, Alio J, Zapater P. Retinal detachment in myopic eyes after phakic intraocular lens implantation. J Cataract Refract Surg. 2006;22:247-52.
Saw S, Chua W, Gazzard G, Goh D, Tan DTH, Stone RA. Eye growth changes in myopic children in Singapore. Br J Ophthalmol. 2005;89:1489-94.
Ortiz A, Galvis V, Tello A, Viaña V, Corrales MI, Ochoa M et al. Comparison of three optical biometers: IOLMaster 500, Lenstar LS 900 and Aladdin. In Ophthalmol. 2019;39(8):1809-18.
Cho YJ, Lim TH, Choi KY, Cho BJ. Comparison of ocular biometry using new swept-source optical coherence tomography-based optical biometer with other devices. Korean J Ophthalmol. 2018;32(4):257-64.
Kim SY, Lee SH, Kim NR, Chin HS, Jung JW. Accuracy of intraocular lens power calculation formulas using a swept-source optical biometer. PLoS One. 2020;15(1):e0227638.
Plat J, Hoa D, Mura F, Busetto T, Schneider C, Payerols A et al. Clinical and biometric determinants of actual lens position after cataract surgery. J Cataract Refract Surg. 2017;43(2):195-200.
Olsen T. Prediction of the effective postoperative (intraocular lens) anterior chamber depth. J Cataract Refract Surg. 2006;32(3):419-24.
Tripathi RC, Tripathi BJ. Lens morphology, aging, and cataract. J Gerontol. 1983;38(3):258-70.
Klein BE, Klein R, Moss SE. Lens thickness and five-year cumulative incidence of cataracts: the Beaver Dam Eye Study. Ophthalmic Epidemiol. 2000;7(4):243-8.
Hashemi H, Khabazkhoob M, Miraftab M, Emamian MH, Shariati M, Abdolahinia T et al. The distribution of axial length, anterior chamber depth, lens thickness, and vitreous chamber depth in an adult population of Shahroud, Iran. BMC Ophthalmol. 2012;12:50.
Jivrajka R, Shammas MC, Boenzi T, Swearingen M, Shammas HJ. Variability of axial length, anterior chamber depth, and lens thickness in the cataractous eye. J Cataract Refract Surg. 2008;34(2):289-94
Warrier S, Wu HM, Newland HS, Muecke J, Selva D, Aung T, Casson RJ. Ocular biometry and determinants of refractive error in rural Myanmar: the Meiktila Eye Study. Br J Ophthalmol. 2008;92(12):1591-4.
Chen H, Lin H, Lin Z, Chen J, Chen W. Distribution of axial length, anterior chamber depth, and corneal curvature in an aged population in South China. BMC Ophthalmol. 2016;16(1):47.
Fotedar R, Wang J, Burlutsky G, Morgan I, Rose K, Wong T et al. Distribution of axial length and ocular biometry measured using partial coherence laser interferometry (IOL Master) in an older white population. Ophthalmology. 2010;117:417-23.
Badmus SA, Ajaiyeoba AI, Adegbehingbe BO, Onakpoya OH, Adeoye AO. Associations between ocular biometry and anthropometric measurements in a Nigerian population. Niger Postgrad Med J. 2016;23:127-31.
He M, Huang W, Zheng Y, Alsbirk PH, Foster PJ. Anterior chamber depth in elderly Chinese: The Liwan Eye Study. Ophthalmology. 2008;115:1286-90.
Foster PJ, Alsbirk PH, Baasanhu J, Munkhbayar D, Uranchimeg D, Johnson GJ. Anterior chamber depth in Mongolians: Variation with age, sex, and method of measurement. Am J Ophthalmol. 1997;124:53-60.
Chinawa EN, Ezeh EI. The distribution of ocular biometrics among patients undergoing cataract surgery. Niger J Ophthalmol. 2018;26:40-5.
Nangia V, Jonas JB, Sinha A, Matin A, Kulkarni M. Central corneal thickness and its association with ocular and general parameters in Indians: the Central India Eye and Medical Study. Ophthalmology. 2010;117(4):705-10.
Jonas JB, Nangia V, Gupta R, Khare A, Sinha A, Agarwal S et al. Anterior chamber depth and its associations with ocular and general parameters in adults. Clin Exp Ophthalmol. 2012;40(6):550-6.
Zhu X, He W, Zhang Y, Chen M, Du Y, Lu Y. Inferior decentration of multifocal intraocular lenses in myopic eyes. Am J Ophthalmol. 2018;188:1-8.