Comparative study between breast conservative surgery and modified radical mastectomy in early stage of breast carcinoma in a tertiary care hospital

Syeda Mehbuba Joty; Noshin Saiyara; M. Tareq Anwar Shishir; Faridul Islam; Mahidur Rahman Khan; Ashok Kumar Sarker; S. M. Mortaza Ahsan; Mohsin Tonoy Nuh

doi:10.18203/2320-6012.ijrms20230562

Authors

Syeda Mehbuba Joty Department of General Surgery, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Noshin Saiyara Department of General Surgery, East Midlands, UK
M. Tareq Anwar Shishir NITOR, Dhaka, Bangladesh
Faridul Islam Northern Ireland Medical & Dental Training Agency, UK
Mahidur Rahman Khan Department of Cardiology, Enam Medical College Hospital, Dhaka, Bangladesh
Ashok Kumar Sarker Department of General Surgery, Enam Medical College Hospital, Dhaka, Bangladesh
S. M. Mortaza Ahsan Department of Surgical Gastroenterology, Sheikh Russel National Gastro-Liver Institute and Hospital, Dhaka, Bangladesh
Mohsin Tonoy Nuh Department of General Surgery, Shaheed Suhrawardy Medical College Hospital, Dhaka, Bangladesh

DOI:

https://doi.org/10.18203/2320-6012.ijrms20230562

Keywords:

Breast cancer, Breast conservative surgery, MRM

Abstract

Background: Breast cancer is the most prevalent cancer in women globally, with two million new cases and more than half a million deaths each year. Surgery is the key component of treating breast cancer and there are two primary types of breast surgery available: breast conservative surgery and modified radical mastectomy. The aim of this study was to compare BCS and MRM in the treatment of early-stage breast carcinoma.

Methods: This was a prospective observational study that involved 74 patients and was carried out in the Department of Surgery at Shaheed Suhrawardy Medical College & Hospital and Enam Medical College & Hospital with an 18-months minimum follow-up. The time frame for inclusion was from July 2018 through July 2020. There were two patient groups, 37 patients in Group A who underwent breast conservative surgery and Group B was made up of 37 individuals who had MRM for early-stage breast carcinoma.

Results: With a mean age of 47.65 years in the BCS group and 48.19 years in the MRM group, the operative time for BCS was 1.04±0.25 hours, whereas 3.20±0.48 hours for MRM. Statistically significant higher amount of post-operative drainage volume in MRM group compared to BCS group (p value=0.000). With an excellent aesthetic outcome rate in BCS group (p value<0.0001) as well as better quality of life than MRM group.

Conclusions: Breast conservative surgery and modified radical mastectomy are both oncologically safe treatments for early-stage breast cancer with multidisciplinary approach. BCS offers less trauma, infection and hospital stay; better aesthetic outcome and quality of life than MRM, making it more deserving of being promoted clinically in the treatment of early-stage breast cancer.

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