Clinico-epidemiological profile of cutaneous tuberculosis at a tertiary care teaching hospital of South Rajasthan

Farzana Ansari; Badrilal Meghwal; Manisha Balai

doi:10.18203/2320-6012.ijrms20231611

Authors

Farzana Ansari Department of Dermatology, Government Medical College, Bharatpur, Rajasthan, India
Badrilal Meghwal Department of Peadiatrics, RNT Medical College, Udaipur, Rajasthan, India
Manisha Balai Department of Dermatology, RNT Medical College, Udaipur, Rajasthan, India

DOI:

https://doi.org/10.18203/2320-6012.ijrms20231611

Keywords:

Cutaneous tuberculosis, Scrofuloderma, Mantoux test, South Rajasthan

Abstract

Background: Cutaneous tuberculosis represents only 1-2% of total tuberculosis cases but due to difficulty in diagnosis even with molecular methods and non-availability of such tests at resource poor set ups, actual burden of cutaneous TB remains under-estimated. The present study was performed to analyse the magnitude and clinico-epidemiological profile of cutaneous tuberculosis at our tertiary level referral centre.

Methods: All the clinically suspected cases of cutaneous tuberculosis attending the dermatology and paediatric outpatient department during a period of 30 months (from October 2015 to March 2018) were enrolled in the study. All patients were subjected to routine blood tests, Chest X-ray, sputum for Ziehl-Neelsen staining, HIV-ELISA, Mantoux test and cutaneous punch biopsy of the lesions for further confirmation.

Results: During the study period of 30 months, total 30 patients were recruited with male to female ratio of 1.5:1 and mean age of 27 years. Mean disease duration was 13 months with head and neck region (60%) being most commonly affected. Most common clinical type of cutaneous tuberculosis was scrofuloderma (60%), followed by lupus vulgaris (26.7%), tuberculosis verrucosa cutis (10%) and papulonecrotic tuberculid (3.3%). Mantoux test was positive in 56.7% patients. All the patients were put on antitubercular treatment as per guidelines of national tuberculosis control programme.

Conclusions: Tuberculosis in developing countries is still an important cause of skin lesions which remains doubtful in most case scenarios even after years of its advent due to difficulty in diagnosis. Clinical diagnosis and therapeutic trials are still helpful in managing most of the cases.

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References

Grange JM. Mycobacteria and the skin. Int J Dermatol. 1982;2:497-503.

Kumar B, Rai R, Kaur I, Sahoo B, Muralidhar S, Radotra BD. Childhood cutaneous tuberculosis: a study over 25 years from northern India. Int J Dermatol. 2001;40:26-32.

Kumar B, Muralidhar S. Cutaneous tuberculosis: A Twenty-year prospective study. Int J Tuberc Lung Dis. 1999;3:494-500.

Santos JB, Fiqueiredo AR. Cutaneous tuberculosis: epidemiologic, etiopathogenic and clinical aspects part I. An Bras Dermatol. 2014;89:219-228.

Frankel A, Penrose C, Emer J. Cutaneous tuberculosis: a pratical case report and review for the dermatologist. J Clin Aesthet Dermatol. 2009;2:19-27.

Barbagallo J, Tager P, Ingleton R, Hirsch RJ, Weinberg JM. Cutaneous tuberculosis: diagnosis and treatment. Am J Clin Dermatol. 2002;3:319-28.

Singh EN, Purohit S, Agarwal US, Meena R, Agarwal S, Agarwal P. Clinico-epidemiological study of cutaneous tuberculosis in a tertiary care hospital of Rajasthan. Int Mult J Health. 2017;3:317-24.

Arora S, Arora G, Kakkar S. Cutaneous Tuberculosis: A Clinico-morphological Study. Med J Armed Forces India. 2006;62:344-7.

Patra AC, Gharami RC, Banerjee PK. A profile of cutaneous tuberculosis. Indian J Dermatol. 2006;51: 105-7.

Puri N. A clinical and histopathological profile of patients with cutaneous tuberculosis. Indian J Dermatol. 2011;56:550-2.

Mathur M and Pandey SN. Clinicohistological Profile of Cutaneous Tuberculosis in Central Nepal. Kathmandu Univ Med J. 2014;12:238-41.

Aruna C, Senthil Kumar AL, Sridevi K, Swapna K, Ramamurthy DVSB. A clinicoepidemiological study of cutaneous tuberculosis in a tertiary care teaching hospital in Andhra Pradesh, India. Int J Res Dermatol. 2017;3:88-93.

Kannan R, Chellappan L, Venu S, Chandrasekar M. A retrospective study on clinicopathological correlation of cutaneous tuberculosis. Int J Res Dermatol. 2018; 4:595-9.

Maghwal N, Jain VK, Chouhan C, Rao P, Choudhary P. A clinicopathological pattern of cutaneous tuberculosis and HIV concurrence in western Rajasthan. Int J Mycobacteriol. 2020;9:429-34.

Varshney A, Goyal T. Incidence of various clinico-morphological variants of cutaneous tuberculosis and HIV concurrence: a study from the Indian subcontinent. Ann Saudi Med. 2011;31:134-9.

Thakur BK, Verma S, Hazarika D. A clinicopathological study of cutaneous tuberculosis at Dibrugarh district, Assam. Indian J Dermatol. 2012;57: 63-5.

Saha PK, Prakash KS. Clinical profile of cutaneous tuberculosis in a tertiary care teaching hospital in Eastern Bihar. Int J Contemp Med Res. 2020;7:1-3.

Zhang J, Fan YK, Wang P, Chen QQ, Wang G, Xu AE, et al. Cutaneous tuberculosis in China - A multicentre retrospective study of cases diagnosed between 1957 and 2013. J Eur Acad Dermatol Venereol. 2018;32: 632-8.

Spelta K, Diniz LM. Cutaneous tuberculosis: a 26-year retrospective study in an endemic area of tuberculosis, Vitória, Espírito Santo, Brazil. Rev Inst Med Trop Sao Paulo. 2016;58:49.

Dwari BC, Ghosh A, Paudel R, Kishore P. A clinicoepidemiological study of 50 cases of cutaneous tuberculosis in a tertiary care teaching hospital in Pokhara, Nepal. Indian J Dermatol. 2010;55:233-6.

Amraoui N, Krich S, Meziane M, Gallouj S, Abid H, Elmrini A, et al. Cutaneous tuberculosis revealing multifocal tuberculosis in immunocompetent patients. Int J Mycobacteriol. 2015;4:255 7.