Study and analysis of maternal serum alpha-fetoprotein levels as a biomarker of placental adherence in low lying placenta

Authors

  • Jashanjot Kaur Department of Obstetrics and Gynaecology, Government Medical College, Amritsar, Punjab, India
  • Amrit Pal Kaur Department of Obstetrics and Gynaecology, Government Medical College, Amritsar, Punjab, India
  • Sukhraj Kaur Department of Biochemistry, Government Medical College, Amritsar, Punjab, India
  • Harjot Kaur Sidhu Department of Obstetrics and Gynaecology, Government Medical College, Amritsar, Punjab, India

DOI:

https://doi.org/10.18203/2320-6012.ijrms20231340

Keywords:

Low lying placenta, MSAFP, Placental adherence

Abstract

Background: The objective was to study and analyze maternal serum alpha-fetoprotein levels as a biomarker of placental adherence in low lying placenta.

Methods: This was a prospective observational study analysing the conditions and the data of 80 cases with low lying placenta in a tertiary care hospital. The analysis was done for the association of MSAFP with MRI, perinatal and maternal outcome.

Results: The level of MSAFP was found higher in 12 out of 13 cases (93.3%) of placenta previa with placental adherence. There was significant surgical intervention (80%) and increased maternal morbidity (68.8%) in the study group with placental adherence and raised MSAFP respectively.

Conclusions: MSAFP is an important biomarker for prognostication of placental adherence in low lying placenta.

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Published

2023-04-29

How to Cite

Kaur, J., Kaur, A. P., Kaur, S., & Sidhu, H. K. (2023). Study and analysis of maternal serum alpha-fetoprotein levels as a biomarker of placental adherence in low lying placenta. International Journal of Research in Medical Sciences, 11(5), 1704–1708. https://doi.org/10.18203/2320-6012.ijrms20231340

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Section

Original Research Articles