A study of relationship between blood parameters with myocardial infractions

Nimisha Gajera, Vishaldeep Gohel, Bhavin Kansagra, Jasmine Parmar

Abstract


Background:The aim of this study was to find out the changes in blood parameters in a group of myocardial infarction patients in Jamnagar, Gujarat.

Methods:In this cross sectional study conducted at the medicine clinic in GGH general hospital, Jamnagar between May 2012 and April 2013, a total of 100 subjects were included. Parameters like hemoglobin, RBC count, WBC count, platelet count, hematocrit, ESR, Mean corpuscular volume, mean corpuscular hemoglobin, mean corpuscular hemoglobin concentration, packed cell volume, differential WBC count used.

Results: The results of present study revealed that WBC count, ESR, the differential leukocyte count (e.g. neutrophil cells) in patients increased significantly (P <0.01) comparison to controls. While, the differential leukocyte count of lymphocyte & platelet count revealed to decrease significantly (P <0.01) in patients.

Conclusion:Abnormal blood parameters are more common among diabetes patients. Elevated WBC count, ESR, neutrophils are present in patients as compared to control. While decreased in lymphocytes & platelets are seen in patients as compared to control.


Keywords


Myocardial infarction, WBC (white blood cells), RBC (red blood cells), MCV (Mean corpuscular volume), MCHC (Mean corpuscular hemoglobin concentration), MCH (Mean corpuscular hemoglobin), PCV (Packed cell volume)

Full Text:

PDF

References


Michel RN, Cotran RS. Cell injury, adaptation, and death. In: Kumar V, Cotran RS, Robbins SL, eds. Robbins Basic Pathology. 7th ed. Philadelphia: W.B. Saunders Company; 2003: 3-31.

Alpert JS, Thygesen K, Antman E, Bassand JP. Myocardial infarction redefined: a consensus document of the joint European society of cardiology/American College of cardiology committee for the redefinition of myocardial infarction. J Am Coll Cardiol. 2000;36(3):959-69.

Akbar DH. Admission blood glucose level is a risk predictor in acute myocardial infarction in non-diabetic patients. Umm-Al Qura Univ J Sci Med Eng. 2001;13(1):31-7.

Boon NA, Colledge NR, Walker BR, Hunter JAA. Echocardiography. In: Boon NA, Colledge NR, Walker BR, Hunter JAA, eds. Davidson’s Principle and Practice of Medicine. 20th ed. US: Elsevier Company; 2006: 591-594.

Marcus GM, Cohen J, Varosy PD, Vessey J, Rose E, Massie BM, et al. The utility of gestures in patients with chest discomfort. Am J Med. 2007;120(1):83-9.

Moe KT, Wong P. Current trends in diagnostic biomarker of acute coronary syndrome. Ann Acad Med Singap. 2010;39(3):210-5.

Corwin Elizabeth J. Electrocardiography. In: Corwin Elizabeth J, eds. Handbook of Pathophysiology. 3rd ed. Philadelphia: Lippincott Williams and Wilkins; 2008: 441.

Grzybowski M, Welch RD, Parsons L, Ndumele CE, Chen E, Zalenski R, et al. The association between white blood cell count and acute myocardial infarction in hospital mortality: findings from national registry of myocardial infarction. Acad Emerg Med. 2004;11:1049-60.

Bax L, Algra A, Mali WP, Edinger M, Beutler JJ, van der Graaf Y, et al. Renal function as a risk indicator for cardiovascular events in 3216 patients with manifest arterial disease. Atherosclerosis. 2008;200(1):184-90.

Zaid Alirhayim, Waqas Qureshi, Vijaya Donthireddy, Syed Hassan, Fatima Khalid. Changes in hemoglobin and hematocrit may predict mortality in patients with acute coronary syndromes. Am Soc Hematol. 2012;54(901):3171.

Toshio Kobayashi, Yuji Miyoshi, Kazue Yamaoka, Eiji Yano. Relationship between hematological parameters and incidence of ischemic heart diseases among Japanese White-Collar male workers. J Occup Health. 2001;43:85-8.

Khalid Al-Fartosi, Raid Al-Salih, Salih J. Batah. Study of relationship between blood parametersand oxidant-antioxidant status of patients with unstable angina pectoris and myocardial infractions. Thi-Qar Med J (TQMJ). 2010;4(1):47-64.

Yaghoubi A, Golmohamadi Z, Alizadehasl A, Azarfarin R. Role of platelet parameters and haematological indices in myocardial infarction and unstable angina. J Pak Med Assoc. 2013 Sep;63(9):1133-7.

Sreekanth KS, Zachariah G, Annamalai PT. Hematological parameters in acute myocardial infarction- a preliminary study. Amala Res Bull. 2000;2:28-31.

Khan HA, Alhomida AS, Sobki SH, Al Moghairi A. Significant increases in monocyte counts and serum creatinine kinase in acute myocardial infarction versus general infections. Indian J Pathol Microbiol. 2012;55:474-7.

Zorio E, Murado J, Arizo D, Rueda J, Corella D, Simó M, et al. Hemorheological parameters in young AMI patients. Clin Hemorheol Microcirc. 2008;39:33-41.

Chafil Saihood Hassan Al-Shujiari. Some hematological and biochemical changes in acute myocardial infarction (MI) in Babylon government. Med J Babylon. 2010;7:511-7.

Tahir Ahmad Munir, Mohammad Nasir Afzal. Assessment of differential leukocyte count in patients with acute coronary syndrome. Am J Cardiol. 2003;91:3A-6A.

Ly HQ, Kirtane AJ, Murphy SA, Buros J, Cannon CP, Braunwald E, et al. Association of platelet counts on presentation and clinical outcomes in ST elevation myocardial infarction (from TIMI trials). Am J Cardiol. 2006 Jul;98(1):1-5.

Nirmala J. Deshpande, K. Raghothama Rao. A comparative study of platelets behavior in controls and acute myocardial infarction patients. Indian J Physiol Pharmacol. 1998;42(2):307-10.

Pizulli L, Yang A, Martin JF, Luderitz B. Change in platelet size and count in unstable angina compared to stable angina or non-cardiac chest pain. Eur Heart J. 1998;19:80-4.

Kung-Ming Jan, Shu Chien, J. Thomas Bigger. Observations on blood viscosity changes after acute myocardial infarction. In: Kung-Ming Jan, Shu Chien, J. Thomas Bigger, eds. 6th ed. A Book. Philadelphia: W. B. Saunders Company an Imprint of Elsevier; 2004: 87-108.

Kirtane AJ, Bui A, Murphy SA, Barron HV, Gibson CM. Association of peripheral neutrophilia with adverse angiographic outcomes in ST-elevation myocardial infarction. Am J Cardiol. 2004 Mar;93(5):532-6.