Partial empty Sella syndrome in women-the significance of obstetric and lactational history
DOI:
https://doi.org/10.18203/2320-6012.ijrms20231661Keywords:
Empty sella, Pituitary gland, Hypophysitis, Adrenal insufficiencyAbstract
Empty Sella syndrome is an uncommon condition characterized by the shrinking or flattening of the pituitary gland, resulting in the filling of the Sella turcica with cerebrospinal fluid rather than the normal pituitary gland. In this report, we present a case of undiagnosed partial empty Sella syndrome, which was found to be caused by pituitary hypophysitis with an idiopathic etiology. The patient, a middle-aged individual, presented atypically with acute adrenal insufficiency induced by a lower respiratory tract infection. The diagnosis was made following an investigative work-up that took into consideration the presence of hypotension, electrolyte imbalances, and a history of two post-partum lactational failures. Hormonal supplements were used to manage the patient conservatively, and no significant complications were observed.
Metrics
References
Maira G, Anile C, Mangiola A. Primary empty Sella syndrome in a series of 142 patients. J Neurosurg. 2005;103(5):831-6.
Hodgson SF, Randall RV, Holman CB, MacCarty CS. Empty sella syndrome. Report of 10 cases. Med Clin N Am. 1972;56(4):897-907.
Caplan RH, Dobben GD. Endocrine studies in patients with "empty Sella syndrome". Psychiatr Digest. 1970;31(7):59.
Chynn PY. Neuroradiologic exploration in intra-and parasellar conditions. Radiologic Clini N Am. 1996;4(1):93-115.
Foresti M, Guidali A, Susanna P. Sella vuota primitiva. Radiol Med. 1991;81:803-7.
Sage MR, Blumbergs PC. Primary empty Sella turcica: a radiological-anatomical correlation. Australasian Radiol. 2000;44.
Sung C, Shen C, Hsu Y, Lin S. Recurrent Hyponatremia as the Presenting Feature of Empty Sella. Research Gate. 2010.
Jakubowski J. Blood supply, blood flow and autoregulation in the adenohypophysis, and altered patterns in oestrogen-induced adenomatous hyperplasia. Br J Neurosurg. 1995;9(3):331-46.
Diederich S, Franzen NF, Bähr V, Oelkers W. Severe hyponatremia due to hypopituitarism with adrenal insufficiency: report on 28 cases. Eur J Endocrinol. 2003;148(6):609-17.
Spasovski G, Vanholder R, Allolio B, Annane D, Ball S, Bichet D et al. Clinical practice guideline on diagnosis and treatment of hyponatraemia. Nephrology, dialysis, transplantation: official publication of the European Dialysis and Transplant Association. Eur Renal Asso. 2014;29(2):i1-39.
Oelkers W. Hyponatremia and inappropriate secretion of vasopressin (antidiuretic hormone) in patients with hypopituitarism. N Eng J Med. 1989;321(8):492-6.