Review on myths about infertility-an attempt to clear the air
DOI:
https://doi.org/10.18203/2320-6012.ijrms20232140Keywords:
Infertility, Myths, MisconceptionsAbstract
Infertility, defined as the inability to conceive after one year of regular unprotected sex, affects 48 million couples and 186 million individuals globally. There are several myths without factual basis regarding infertility, with the increase in prevalence of infertility in the world, the spread of such myths also increases. Such myths include concepts like infertility is a woman’s problem, it is a psychological or stress induced issue, health and lifestyle habits do not affect infertility. While others include, misconceptions about medications and treatment, some supernatural beliefs, frequency of sexual contact, sexual practices which do not have any positive impact on infertile couples. These are few among many other stories revolving around fecundity. Myths about reproductive health and chances of conception may directly or indirectly affect the emotional state of infertile couples or may give a false hope for them to get conceive faster and easier, which have no evidence. Some of the myths might not be harmful, or even do some good, but many of the prevailing myths put infertile couples, especially infertile women in an excruciating position leading to a great deal of mental distress. It is thus important to root out the myths about infertility and help the affected ones lead a less stressful life. This article is an attempt to bust some of the most common myths being spread and explains the actual facts that should be known to people of the reproductive age group.
References
WHO. International Classification of Diseases, 11th Revision (ICD-11) Geneva: WHO 2018. Available at: https://www.who.int/news/item/18-06-2018-who-releases-new-international-classification-of-diseases-(icd-11). Accessed on 1 April 2023.
Rastogi A. Infertility. National Health Portal of India. 2016. Available at: https://www.nhp.gov.in/disease/reproductive-system/infertility. Accessed on 2 March, 2023.
Mascarenhas MN, Flaxman SR, Boerma T, Vanderpoel S, Stevens GA. National, regional, and global trends in infertility prevalence since 1990: a systematic analysis of 277 health surveys. PLoS Medicine. 2012;9(12):e1001356.
Boivin J, Bunting L, Collins JA, Nygren KG. International estimates of infertility prevalence and treatment-seeking: potential need and demand for infertility medical care. Human Reproduction. 2007;22(6):1506-12.
WHO. Infecundity infertility and childlessness in developing countries. Geneva: World Health Organization. 2004. Available at: https://www.who.int/publications/m/item/infecundity-infertility-and-childlessness-in-developing-countries---dhs-comparative-reports-no.-9. Accessed on 1 April 2023.
Mahey R, Gupta M, Kandpal S. Fertility awareness and knowledge among Indian women attending an infertility clinic: a cross-sectional study. BMC Womens Health. 2018;18(1):177.
Bergstrom S. Reproductive failure as a health priority in the Third World: a review. East African Med J. 1992;69(4):174-80.
Frank O. Infertility in sub-Saharan Africa: estimates and implications. Population Develop Rev. 1983;9(1):137-44.
Gerrits T. Social and cultural aspects of infertility in Mozambique. Patient Education Counselling. 1997;31(1):39-48.
Greil AL. Infertility and psychological distress: a critical review of the literature. Social Sci Med. 1997;45(11):1679-704.
Kielmann K. Barren ground: contesting identities of infertile women in Pemba, Tanzania. In: Lock M, Kaufert PA, eds. Pragmatic women and body politics. Cambridge, Cambridge University Press. 1998:127-63.
Papreen N, Sharma A, Sabin K, Begum L, Ahsan SK, Baqui AH. Living with infertility: experiences among Urban slum populations in Bangladesh. Reproductive Health Matters. 2000;8(15):33-44.
Unisa S. Childlessness in Andhra Pradesh, India: Treatment-seeking and consequ ences. Reproductive Health Matters. 1999;7(13):54-64.
Whiteford LM, Gonzalez L. Stigma: the hidden burden of infertility. Social Sci Med. 1995;40(1):27-36.
Buxton RG, Bolle KW, Smith JZ. Myth. Encyclopedia Britannica. 2004. Available at: https://www.britannica.com/topic/myth. Accessed on 18 April 2023.
Bunting L, Boivin J. Knowledge about infertility risk factors, fertility myths and illusory benefits of healthy habits in young people. Human Reproduction. 2008;23(8):1858-64.
Ali S, Sophie R, Imam AM. Knowledge, perceptions and myths regarding infertility among selected adult population in Pakistan: a cross-sectional study. BMC Public Health. 2011;11(1):760.
Purkayastha N, Sharma H. Prevalence and potential determinants of primary infertility in India: Evidence from Indian demographic health survey. Clin Epidemiol Global Health. 2021;9:162-70.
Sun H, Gong TT, Jiang YT, Zhang S, Zhao YH, Wu QJ. Global, regional, and national prevalence and disability-adjusted life-years for infertility in 195 countries and territories, 1990-2017: results from a global burden of disease study, 2017. Aging (Albany NY). 2019;11(23):10952-91.
Agarwal A, Mulgund A, Hamada A, Chyatte MR. A unique view on male infertility around the globe. Reproductive Biol Endocrinol. 2015;13:37.
Agarwal A, Baskaran S, Parekh N. Male infertility. Lancet. 2021;397(10271):319-33.
Jungwirth A, Diemer T, Kopa Z, Krausz C, Minhas S, Tournaye H. EAU guidelines on male infertility. Arnhem, The Netherlands: European Association of Urology. 2015. Available at: https://uroweb.org/wp-content/uploads/EAU-Guidelines-Male-Infertility-20151.pdf. Accessed on 22 April, 2023.
Chehab M, Madala A, Trussell JC. On-label and off-label drugs used in the treatment of male infertility. Fertil Steril. 2015;103(3):595-604.
World Health Organization. Infertility: a tabulation of available data on prevalence of primary and secondary infertility. Programme of Maternal and Child Health and Family Planning Unit. Geneva: World Health Organization. 1991. Available at: https://apps.who.int/iris/bitstr eam/handle/10665/59769/WHO_MCH_91.9.pdf?sequence=1&isAllowed=y. Accessed on 22 April, 2023.
Mascarenhas MN, Flaxman SR, Boerma T, Vanderpoel S, Stevens GA. National, regional, and global trends in infertility prevalence since 1990: a systematic analysis of 277 health surveys. PLoS Med. 2012;9(12):e1001356.
Larsen U. Primary and secondary infertility in sub-Saharan Africa. Int J Epidemiol. 2000;29(2):285-91.
Sedgh G, Singh S, Shah IH, Ahman E, Henshaw SK, Bankole A. Induced abortion: incidence and trends worldwide from 1995 to 2008. Lancet. 2012;379(9816):625-32.
Momtaz H, Flora M, Shirin S. Factors associated with secondary infertility. Ibrahim Med College J. 2012;5(1):17-21.
Sami N, Ali TS, Wasim S, Saleem S. Risk factors for secondary infertility among women in Karachi, Pakistan. PLoS One. 2012;7(4):e35828.
Katib AA, Al-Hawsawi K, Motair W, Bawa AM. Secondary infertility and the aging male, overview. Central Eur J Urol. 2014;67(2):184-8.
Johnson SL, Dunleavy J, Gemmell NJ, Nakagawa S. Consistent age-dependent declines in human semen quality: a systematic review and meta-analysis. Ageing Res Rev. 2015;19:22-33.
Gill K, Jakubik-Uljasz J, Rosiak-Gill A, Grabowska M, Matuszewski M, Piasecka M. Male aging as a causative factor of detrimental changes in human conventional semen parameters and sperm DNA integrity. The Aging Male. 2020;23(5):1321-32.
Pino V, Sanz A, Valdés N, Crosby J, Mackenna A. The effects of aging on semen parameters and sperm DNA fragmentation. JBRA assisted reproduction. 2020;24(1):82.
Myrskylä M, Fenelon A. Maternal age and offspring adult health: evidence from the health and retirement study. Demography. 2012;49(4):1231-57.
Belloc S, Hazout A, Zini A, Merviel P, Cabry R, Chahine H et al. How to overcome male infertility after 40: Influence of paternal age on fertility. Maturitas. 2014;78(1):22-9.
Hull MG, North K, Taylor H, Farrow A, Ford WC. Delayed conception and active and passive smoking. Fertil Steril. 2000;74(4):725-33.
Weisberg E. Smoking and reproductive health. Clin Reproduct Fertil. 1985;3(3):175-86.
Stillman RJ, Rosenberg MJ, Sachs BP. Smoking and reproduction. Fertil Steril. 1986;46(4):545-66.
Fredricsson B, Gilwam H. Smoking and reproduction: Short and long term effects and benefits of smoking cessation. Acta Obstetricia et Gynecol Scandinavica. 1992;71(8):580-92.
Wallach EE, Hughes EG, Brennan BG. Does cigarette smoking impair natural or assisted fecundity? Fertil Steril. 1996;66(5):679-89.
Augood C, Duckitt K. Templeton AJHr. Smoking and female infertility: a systematic review and meta-analysis. Human Reproduct. 1998;13(6):1532-9.
Gaur DS, Talekar M, Pathak VP. Effect of cigarette smoking on semen quality of infertile men. Singapore Med J. 2007;48(2):119-23
Sharma R, Biedenharn KR, Fedor JM, Agarwal A. Lifestyle factors and reproductive health: taking control of your fertility. Reproductive Biol Endocrinol. 2013;11(1):1-5.
Cook CL, Siow Y, Brenner AG, Fallat ME. Relationship between serum müllerian-inhibiting substance and other reproductive hormones in untreated women with polycystic ovary syndrome and normal women. Fertil Steril. 2002;77(1):141-6.
Dechanet C, Anahory T, Mathieu Daude JC, Quantin X, Reyftmann L, Hamamah S et al. Effects of cigarette smoking on reproduction. Human Reproduct Update. 2011;17(1):76-95.
Silvestris E, Lovero D, Palmirotta R. Nutrition and Female Fertility: An Interdependent Correlation. Front Endocrinol (Lausanne). 2019;10:346.
Silvestris E, De Pergola G, Rosania R, Loverro G. Obesity as disruptor of the female fertility. Reproduct Biol Endocrinol. 2018;16(1):1-3.
Skoracka K, Eder P, Lykowska-Szuber L, Dobrowolska A, Krela-Kazmierczak I. Diet and Nutritional Factors in Male (In)fertility-Underestimated Factors. J Clin Med. 2020;9(5):1400.
Magnusdottir EV, Thorsteinsson T, Thorsteinsdottir S, Heimisdottir M, Olafsdottir K. Persistent organochlorines, sedentary occupation, obesity and human male subfertility. Human Reproduct. 2005;20(1):208-215.
Li Y, Lin H, Li Y, Cao J. Association between socio-psycho-behavioral factors and male semen quality: systematic review and meta-analyses. Fertil Steril. 2011;95(1):116-23.
Gollenberg AL, Liu F, Brazil Cl. Semen quality in fertile men in relation to psychosocial stress. Fertil Steril. 2010;93(4):1104-11.
Schweiger U, Deuschle M, Weber B. Testosterone, gonadotropin, and cortisol secretion in male patients with major depression. Psychosomaic Med. 1999;61(3):292-6.
Volgsten H, Skoog Svanberg A, Ekselius L, Lundkvist O, Sundstrom Poromaa I. Prevalence of psychiatric disorders in infertile women and men undergoing in vitro fertilization treatment. Human Reproduct. 2008;23(9):2056-63.
Mutsaerts MA, Groen H, Huiting HG. The influence of maternal and paternal factors on time to pregnancy--a Dutch population-based birth-cohort study: the GECKO Drenthe study. Human Reproduct. 2012;27(2):583-93.
Louis GM, Lum KJ, Sundaram R. Stress reduces conception probabilities across the fertile window: evidence in support of relaxation. Fertil Steril. 2011;95(7):2184-9.
Domar AD, Clapp D, Slawsby EA, Dusek J, Kessel B, Freizinger M. Impact of group psychological interventions on pregnancy rates in infertile women. Fertil Steril. 2000;73(4):805-11.
Terzioglu F. Investigation into effectiveness of counseling on assisted reproductive techniques in Turkey. J Psychosomatic Obstetr Gynecol. 2001;22(3):133-41.
Wilcox AJ, Weinberg CR, Baird DD. Timing of sexual intercourse in relation to ovulation. Effects on the probability of conception, survival of the pregnancy, and sex of the baby. Eng J Med. 1995;333(23):1517-21.
Wilcox AJ, Dunson D, Baird DD. The timing of the "fertile window" in the menstrual cycle: day specific estimates from a prospective study. BMJ. 2000;321(7271):1259-62.
Macleod J, Gold RZ. The male factor in fertility and infertility. V. Effect of continence on semen quality. Fertil Steril. 1952;3(4):297-315.
Freund M. Interrelationships among the characteristics of human semen and factors affecting semen-specimen quality. Reproduction. 1962;4:143-59.
Poland ML, Moghissi KS, Giblin PT, Ager JW, Olson JM. Variation of semen measures within normal men. Fertil Steril. 1985;44(3):396-400.
Dunson DB, Baird DD, Wilcox AJ, Weinberg CR. Day-specific probabilities of clinical pregnancy based on two studies with imperfect measures of ovulation. Human Reproduct. 1999;14(7):1835-9.
Baird DD, Weinberg CR, Zhou H, et al. Preimplantation urinary hormone profiles and the probability of conception in healthy women. Fertil Steril. 1999;71(1):40-49.
Sunanda P, Panda B, Dash C, Padhy RN, Routray P. Effect of age and abstinence on semen quality: A retrospective study in a teaching hospital. Asian Pacific J Reproduct. 2014;3(2):134-41.
Hanson BM, Aston KI, Jenkins TG, Carrell DT, Hotaling JM. The impact of ejaculatory abstinence on semen analysis parameters: a systematic review. J Assisted Reproduct Genetics. 2018;35(2):213-20.
Levitas E, Lunenfeld E, Weiss N. Relationship between the duration of sexual abstinence and semen quality: analysis of 9,489 semen samples. Fertil Steril. 2005;83(6):1680-6.
AlAwlaqi A, Hammadeh M. Sexual Abstinence and Sperm Quality. Int J Women's Health Reproduct Sci. 2017;5(1):11-7.
Ayad B, Van der Horst G, Du Plessis S. Short abstinence: A potential strategy for the improvement of sperm quality. Middle East Fertil Society J. 2018;23(1):37-43.
Practice Committee of American Society for Reproductive Medicine in collaboration with Society for Reproductive Endocrinology and Infertility. Optimizing natural fertility: a committee opinion. Fertil Steril. 2013;100(3):631-7.
Settlage DS, Motoshima M, Tredway DR. Sperm transport from the external cervical os to the fallopian tubes in women: a time and quantitation study. Fertil Steril. 1973;24(9):655-61.
Farrow A, Hull MG, Northstone K, Taylor H, Ford WC, Golding J. Prolonged use of oral contraception before a planned pregnancy is associated with a decreased risk of delayed conception. Human Reproduct. 2002;17(10):2754-61.
Bagwell MA, Thompson SJ, Addy CL, Coker AL, Baker ER. Primary infertility and oral contraceptive steroid use. Fertil Steril. 1995;63(6):1161-6.
Vercellini P, Ragni G, Trespidi L, Oldani S, Crosignani PG. Does contraception modify the risk of endometriosis? Human Reproduct. 1993;8(4):547-51.
Vessey MP, Villard-Mackintosh L, Painter R. Epidemiology of endometriosis in women attending family planning clinics. BMJ. 1993;306(6871):182-4.
Milman N, Kirchhoff M, Jorgensen T. Iron status markers, serum ferritin and hemoglobin in 1359 Danish women in relation to menstruation, hormonal contraception, parity, and postmenopausal hormone treatment. Ann Hematol.1992;65(2):96-102.
Weisberg E. Fertility after discontinuation of oral contraceptives. Clin Reproduct Fertil. 1982;1(4):261-72.
Hanson F, Rock J. The Effect of Adoption on Fertility and other Reproductive Functions. Am J Obstetr Gynecol. 1950;59(2):311-20.
Wallach EE, Seibel MM, Taymor ML. Emotional aspects of infertility. Fertil Steril. 1982;37(2):137-45.
Rock J, Tietze C, Mclaughlin HB. Effect of adoption on infertility. Fertility and Sterility. 1965;16(3):305-12.
Apfel RJ, Keylor RG. Psychoanalysis and infertility. Myths and realities. Int J Psycho-analysis. 2002;83(1):85-104.
Wischmann TH. Psychogenic infertility--myths and facts. J Assisted Reproduct Genetics. 2003;20(12):485-94.
Buchanan JF, Davis LJ. Drug-induced infertility. Drug Intelligence Clin Pharmacy. 1984;18(2):122-32.
Sherif BQ, Al-Zohyri AM, Shihab SS. Effects of Some Non-Steroidal Anti-inflammatory Drugs on Ovulation in Women with Mild Musculoskeletal Pain (A Clinical Study). J Pharmacy Biological Sci. 2014;9(4):43-9.
Cunningham J. Infertility: A primer for primary care providers. J Am Academy Physician Assistants. 2017;30(9):19-25.
Lindsay TJ, Vitrikas KR. Evaluation and treatment of infertility. Am Family Physician. 2015;91(5):308-14.
Leeton J. The management of infertility: where to stop. Clin Reproduct Fertil. 1982;1(4):249-59.
Maroufizadeh S, Karimi E, Vesali S, Omani Samani R. Anxiety and depression after failure of assisted reproductive treatment among patients experiencing infertility. Int J Gynecol Obstetr. 2015;130(3):253-6.
Muscatello MR, Lorusso S, Bruno Al. Anger in women treated with assisted reproductive technology (ART): effects on mother and newborn. J Maternal-fetal Neonatal Med. 2016;29(5):813-7.
Boivin J, Griffiths E, Venetis CA. Emotional distress in infertile women and failure of assisted reproductive technologies: meta-analysis of prospective psychosocial studies. BMJ. 2011;342:d223.
Katz P, Showstack J, Smith JF. Costs of infertility treatment: results from an 18-month prospective cohort study. Fertil Steril. 2011;95(3):915-21.
Reis S, Xavier MR, Coelho R, Montenegro N. Psychological impact of single and multiple courses of assisted reproductive treatments in couples: a comparative study. Eur J Obstetr Gynecol Reproduct Biol. 2013;171(1):61-6.
Roudsari RL, Allan HT, Smith PA. Looking at infertility through the lens of religion and spirituality: a review of the literature. Human Fertil. 2007;10(3):141-9.
Klitzman R. How Infertility Patients and Providers View and Confront Religious and Spiritual Issues. J Religion Health. 2018;57(1):223-9.
Pargament KI, Koenig HG, Tarakeshwar N, Hahn J. Religious coping methods as predictors of psychological, physical and spiritual outcomes among medically ill elderly patients: a two-year longitudinal study. J Health Psychol. 2004;9(6):713-30.
Hobek Akarsu R, Kızılkaya Beji N. Spiritual and Religious Issues of Stigmatization Women with Infertility: A Qualitative Study. J Religion Health. 2021;60(1):256-67.
