Epstein Barr virus induced pneumonitis: a rare entity in immunocompetent baby

Authors

  • Vineet K. Singh Department of Pediatrics, Midland Health Care and Research Centre, Lucknow, Uttar Pradesh, India
  • Manisha Verma Dr. Ram Manohar Lohia Institute of Medical Sciences, Lucknow, Uttar Pradesh, India
  • Yarraguntla K. Kumar Department of Pediatrics, Churg District Hospital, Bhilai Nagar City, Chhattisgarh, India
  • Mithlesh Bhargav Department of Pathology, RML Pathology, Lucknow, Uttar Pradesh, India

DOI:

https://doi.org/10.18203/2320-6012.ijrms20232439

Keywords:

EBV, Immunocompetent child, Pneumonitis

Abstract

Acute infectious interstitial pneumonitis (IP) (Epstein Barr virus (EBV)-associated IP) in children has been most commonly associated with human immunodeficiency virus (HIV) infection and immunocompromised hosts. Here we report a case of EBV-associated interstitial pneumonitis with cervical lymphadenopathy in an immunocompetent child. Patient underwent extensive routine and serologic workup which revealed positive polymerase chain reaction (PCR) for EBV, pointing towards the diagnosis of EBV induced pneumonitis. It is a very rare entity and is hardly seen among immunocompetent individuals especially young children. The aim of this case report is to bring to our notice that among all described pneumonias, EBV induced pneumonitis can be a possibility while dealing with lung infections.

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References

Teirstein AS, Rosen MJ. Lymphocytic interstitial pneumonitis. Clin Chest Med. 1988;9:467-71.

Katz BZ, Beckman AB, Shapiro ED. Serologic evidence of active Epstein-Barr virus infection in Epstein-Barr virus associated lymphoproliferative disorders of children with acquired immunodeficiency syndrome. J Pediatr. 1992;120:228-32.

Fugl A, Andersen CL. Epstein-Barr virus and its association with disease - a review of relevance to general practice. BMC Fam Pract. 2019;20(1):62.

Dunmire SK, Hogquist KA, Balfour HH. Infectious Mononucleosis. Curr Top Microbiol Immunol. 2015;390(Pt 1):211-40.

Khoo A. Acute cholestatic hepatitis induced by Epstein-Barr virus infection in an adult: a case report. J Med Case Rep. 2016;10:75.

Odumade OA, Hogquist KA, Balfour HH. Progress and problems in understanding and managing primary Epstein-Barr virus infections. Clin Microbiol Rev. 2011;24(1):193-209.

Kimura H. Pathogenesis of chronic active Epstein-Barr virus infection: is this an infectious disease, lymphoproliferative disorder, or immunodeficiency? Rev Med Virol. 2006;16(4):251-61.

Ankermann T, Claviez A, Wagner HJ, Krams M, Riedel F. Chronic interstitial lung disease with lung fibrosis in a girl: uncommon sequelae of Epstein-Barr virus infection. Pediatr Pulmonol. 2003;35:234-8.

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Published

2023-07-29

How to Cite

Singh, V. K., Verma, M., Kumar, Y. K., & Bhargav, M. (2023). Epstein Barr virus induced pneumonitis: a rare entity in immunocompetent baby. International Journal of Research in Medical Sciences, 11(8), 3023–3025. https://doi.org/10.18203/2320-6012.ijrms20232439

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Section

Case Reports