Expect the unexpected: a case report of bacterial meningitis causing Guillain-Barré syndrome in an immunocompetent person

Authors

  • Joycel Angelique F. Chua Department of Neurosciences, East Avenue Medical Center, Quezon City, Philippines

DOI:

https://doi.org/10.18203/2320-6012.ijrms20233041

Keywords:

Meningitis, Guillain-Barre syndrome, Polyradiculoneuropathy, CNS infection

Abstract

This is the case report of a 36-year-old male presenting as acute onset of progressive bilateral lower extremity weakness, initially managed as a case of Guillain-Barré Syndrome (GBS). However, his cerebrospinal fluid tested positive for Neisseria meningitidis Y, Neisseria meningitidis W135, Streptococcus group B antigen, and Streptococcus pneumoniae. The patient was later treated for bacterial meningitis. Most cases of GBS are preceded by an upper respiratory infection or gastroenteritis. There are only a few reported cases of bacterial meningitis occurring coincidentally with GBS, much more in an immunocompetent individual. This is a rare case of such with good patient recovery and outcome.

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References

Ropper A, Samuels M, Klein J. Adams and Victor’s Principles of Neurology. 10th ed. McGraw Hill Education; 2014.

Guillain-Barré Syndrome and Vaccines. Centers for Disease Control and Prevention. Accessed last April 2023. Available at: https://www.cdc.gov/vaccinesafety/concerns/guillain-barre-syndrome.html. Accessed on 2 August 2023.

Nguyen TP, Taylor RS. Guillain-Barré syndrome. Treasure Island (FL): StatPearls; 2023.

Amante JMG, Presyler MG. Clinical profile and outcomes of Guillain-Barré syndrome: a four-year retrospective study at a tertiary hospital in the Philippines. IJRP. 2021;73(1):119-28.

Wachira VK, Farinasso CM, Silva RB, Peixoto HM, Oliveira MRFD. Incidence of Guillain-Barré syndrome in the world between 1985 and 2020: a systematic Review. Glob Epidemiol. 2023;5:100098.

Illes Z, Blaabjerg M. Cerebrospinal fluid findings in Guillain–Barré syndrome and chronic inflammatory demyelinating polyneuropathies. Handb Clin Neurol. 2017;146:125-38.

Yoon BA, Bae JS, Kim JK. Electrognostic findings of Guillain-Barre syndrome. Ann Clin Neurophysiol. 2020;22(1):1-7.

Espiritu AI, Separa KJNJ, Milla FJC, Adiao KJB, Leochico CFD, Jamora RDG. Clinical features and real-world outcomes of Guillain-Barré syndrome in the Philippines. Neurol Res. 2021;43(12):995-1004.

HoffmanO, Weber RJ. Pathophysiology and treatment of bacterial meningitis. Ther Adv Neurol Disord. 2009;2(6):1-7.

Runde TJ, Anjum F, Hafner JW. Bacterial meningitis. Treasure Island (FL): StatPearls Publishing; 2023.

Hrishi AP, Sethuraman M. Cerebrospinal fluid (CSF) analysis and interpretation in neurocritical care for acute neurological conditions. Indian J Crit Care Med. 2019;23(2):115-9.

Ding L, Chen Z, Sun Y, Bao H, Wu X, Zhong L, et al. Guillain-Barré syndrome following bacterial meningitis: a case report and literature review. BMC Neurol. 2018;18(1):208.

Khangarot D, Panegyres PK. Guillain-Barré syndrome complicating Neisseria meningitidis infection. Oxford Med Case Rep. 2022;4:33.

Wright JK, Castellani L, Lecce C, Khatib A, Bonta M, Boggild AK. Zika virus-associated aseptic meningitis and Guillain-Barré syndrome in a traveler returning from Latin America: a case report and mini-review. Curr Infect Dis Rep. 2019;21(1):3.

Abdallah MA, Ahmed KM, Recio-Restrepo MV, Khalid M, Yeddi A, Abu-Heija A, et al. Pneumococcal meningitis complicated by spinal cord dysfunction and acute polyradiculopathy. Ochsner J. 2020;20(2):219-21.

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Published

2023-09-29

How to Cite

Chua, J. A. F. (2023). Expect the unexpected: a case report of bacterial meningitis causing Guillain-Barré syndrome in an immunocompetent person. International Journal of Research in Medical Sciences, 11(10), 3830–3833. https://doi.org/10.18203/2320-6012.ijrms20233041

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Section

Case Reports