Pancreatitis with pancytopenia: are we missing a common diagnosis?
DOI:
https://doi.org/10.18203/2320-6012.ijrms20233405Keywords:
Acute pancreatitis, Pancytopenia, Dengue feverAbstract
Acute pancreatitis with pancytopenia is a rare unreported complication of dengue non-hemorrhagic fever. A 16-year-old girl came to the emergency with complaints of loose stools and vomiting with pain abdomen and mild fever the previous day. She was diagnosed to have acute pancreatitis, which evolved into pancytopenia. She was then diagnosed with dengue fever. She was successfully managed conservatively nil orally, with intravenous fluids therapy as per the dengue protocol, timely investigations and watchful management. Acute pancreatitis with pancytopenic blood picture must point the clinician to underlying causes like dengue in endemic areas.
References
Gapp J, Tariq A, Chandra S. Acute Pancreatitis. In: StatPearls. Treasure Island (FL): StatPearls Publishing; 2023. Available at: https://www.ncbi.nlm.nih.gov/books/NBK482468/. Accessed on 15 February, 2023.
Ortiz MCM, Girela BEL, Olalla MJR, Parlorio AE, López CJA. Radiology of acute pancreatitis today: the Atlanta classification and the current role of imaging in its diagnosis and treatment. Radiologia (Engl Ed). 2019;61(6):453-66.
Fonseca Sepúlveda EV, Guerrero-Lozano R. Acute pancreatitis and recurrent acute pancreatitis: an exploration of clinical and etiologic factors and outcomes. J Pediatr. 2019;95(6):713-9.
Khanna S, Vij JC, Kumar A, Singal D, Tandon R. Etiology of abdominal pain in dengue fever. Dengue Bull. 2005;29:85-8.
Dibya JS, Vishal S, Sobur UA, Ravi KS, Rajesh G, Surinder SR. Acute Pancreatitis due to Dengue: Report of an Uncommon Complication and Literature Review. Trop Gastroenterol. 2018;39(4):218-22.
Naik S, Mahajan S, Talwar D, Jagtap G. Acute pancreatitis complicating a case of dengue fever: Double Trouble. Cureus. 2021;3(11):e19523.
Jain V, Gupta OP, Rao T, Rao S. Acute pancreatitis complicating severe dengue. J Glob Infect Dis. 2014;6(2):76.
Flor MA, Andrade JV, Bucaram JA. Acute pancreatitis secondary to dengue fever: An uncommon presentation of a common endemic illness. Case Rep Infect Dis. 2022;2022:1-7.
Han CQ, Xie XR, Zhang Q, Ding Z, Hou XH. Hemophagocytic syndrome as a complication of acute pancreatitis: A case report. World J Clin Cases. 2020;8(11):2364-73.
Sarangapani A, Samal SC, Sahu MK, Chandy GM. Autoimmune pancreatitis with pancytopenia: A rare occurrence. Sahel Med J. 2016;19:101-3.
Deshpande SV, Godbole VY, Asher AD. Pancytopenia: the perspective from Western Gujarat, India. Int J Adv Med. 2019;6:731-7.
Mohammed R, Satya PY, Anupam S. Post-dengue fever severe aplastic anemia: a rare association. Hematol. Oncol. Stem Cell Ther. 2012;5(2):122-4.