Rosai-Dorfman disease in a child with involvement of extra-nodal wrist joint

Rajjyoti Das, Jagannath Dev Sharma, Nizara Baishya, Manigreeva Krishnatreya, Binoy Kumar Choudhary, Amal Chandra Kataki

Abstract


Rosai-Dorfman Disease (RDD) is a benign condition primarily affecting the lymph nodes. The term sinus histiocytosis with massive lymphadenopathy was first used. There may be extra-nodal presentation of RDD with or without constitutional symptoms. A 10-year-old boy presented with massive bilateral cervical lymphadenopathy which mimicked the diagnosis of lymphoma. We describe here a case of RDD in a child with extra-nodal bone involvement of the wrist joint, its diagnosis by histopathological examination supported by immunohistochemistry and consequent initial management.


Keywords


Bone involvement, Child, Lymphadenopathy, Rosai-Dorfman disease

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References


Rosai J, Dorfman RF. Sinus histiocytosis with massive lymphadenopathy, a newly recognized benign clinicopathological entity. Arch Pathol. 1969;87:63-70.

Levine PH, Jahan N, Murari P, Manak M, Jaffe ES. Detection of human herpesvirus 6 in tissues involved by sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman disease). J Infect Dis. 1992;166:291-5.

Tsang WY, Yip TT, Chan JK. The Rosai-Dorfman disease histiocytes are not infected by Epstein-Barr virus. Histopathology. 1994;25:88-90.

Rodriguez-Galindo C, Helton KJ, Sanchez ND, Rieman M, Jeng M, Wang W. Extra nodal Rosai-Dorfman disease in children. J Pediatr Hematol Oncol. 2004;26:19-24.

Rosai J, Dorfman RF. Sinus histicytosis with massive lymphadenopathy. Arch Pathol. 1996;89:68-71.

Pulsoni A, Anghei G, Falcucci P, Matera R, Pescarmona E, Ribersani M, et al. Treatment of sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman disease): report of a case and literature review. Am J Hematol. 2002;69:67-71.

Demicco EG, Rosenberg AE, Bjomsson J, Rybak LD, Unni KK, Nielson GP. Primary Rosai-Dorfman disease of bone: a clinicopathologic study of 15 cases. Am J Surg Pathol. 2010;34:1324-33.

Hashimoto K, Kariya S, Onoda T, Ooue T, Yamashita Y, Naka K, et al. Rosai-Dorfman disease with extranodal involvement. Laryngoscope. 2014;124:701-4.

Orvets ND, Mayerson JL, Wakely PE Jr. Extranodal Rosai-Dorfman disease as solitary lesion of the tibia in a 56-year-old woman. Am J Orthop (Belle Mead NJ). 2013;42:420-9.

Duijsens HM, Vanhoenacker FM, ter Braak BP, Hogendoorn PC, Kroon HM. Primary intraosseous manifestation of Rosai-Dorfman disease: 2 cases and review of literature. JBR-BTR. 2014;97:84-9.

El Molla M, Mahasneh T, Holmes SE, Al-Khawaja D. Rare presentation of Rosai-Dorfman disease mimicking a cervical intramedullary spinal cord tumor. World Neurosurg. 2014;81:442.e7-9.

Juskevicius R, Finlay JL. Rosai-Dorfman disease of the parotid gland, cytologic and histopathologic findings with immunohistochemical correlation. Arch Pathol Lab Med. 2001;125:1348-50.

Rosai J, Dorfman RF. Sinus histocytosis with massive lymphadenopathy: a pseudolymphomatous benign disorder: analysis of 34 cases. Cancer. 1972;30:1174-88.

Zaveri J, La Q, Yarmish G, Neuman J. More than just Langerhans cell histiocytosis: a radiologic review of histiocytic disorders. Radiographics. 2014;34:2008-24.

Tasso M, Esquembre C, Blanco E, Mescardo C, Niveiro M, Paya A. Sinus histocytosis with massive lymphadenopathy (DD) treated with 2- chlorodeoxyadenosine. Pediatr Blood Cancer. 2006;47;612-5.

Ahmed MM, Yasser B, Tunio M, Wafaa A, Dahar MA, Shomaila AA. Steroid resistant extranodal rosai-dorfman disease of cheek mass and ptosis treated with radiation therapy. Case Rep Hematol. 2013;2013:428297.

Huang Q, Chang KL, Weiss LM. Extranodal Rosai-dorfman disease involving the bone marrow: a rare case report. Am J Surg Pathol. 2006;30:1189-92.