Rosai-Dorfman disease in a child with involvement of extra-nodal wrist joint

Rajjyoti Das, Jagannath Dev Sharma, Nizara Baishya, Manigreeva Krishnatreya, Binoy Kumar Choudhary, Amal Chandra Kataki


Rosai-Dorfman Disease (RDD) is a benign condition primarily affecting the lymph nodes. The term sinus histiocytosis with massive lymphadenopathy was first used. There may be extra-nodal presentation of RDD with or without constitutional symptoms. A 10-year-old boy presented with massive bilateral cervical lymphadenopathy which mimicked the diagnosis of lymphoma. We describe here a case of RDD in a child with extra-nodal bone involvement of the wrist joint, its diagnosis by histopathological examination supported by immunohistochemistry and consequent initial management.


Bone involvement, Child, Lymphadenopathy, Rosai-Dorfman disease

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