Frequency and pattern of congenital heart defects among admitted patient in a tertiary care hospital in Bangladesh
DOI:
https://doi.org/10.18203/2320-6012.ijrms20233143Keywords:
CHD, VSDs, TOF, Cyanotic heart defect, DextrocardiaAbstract
Background: Congenital heart disease (CHD) is the commonest of all congenital lesions accounting for nearly 28% of all congenital malformations that have significant impact on morbidity, mortality and heath care cost in children. The aim of study was to determine the pattern of distribution of CHD and the age at which initial diagnosis of CHD was made among children admitted under paediatric cardiology department, Bangladesh Shishu hospital and institute.
Methods: This is a descriptive and prospective hospital-based study conducted in the pediatric cardiology department, Bangladesh Shishu hospital and institute. This study included all the patients admitted during January-June 2022 in pediatric cardiology department having confirmed diagnosis of CHD on basis of echocardiographic report. The collected data was entered and analyzed by using statistical package for social sciences v 24.0.
Results: Out of 337 patient, 175 patient were male (51.9%) and 162 female (48.1%) with male female ratio of 1.08:1. Total 219 cases (64.9%) were acyanotic CHD and 118 (35.1%) were cyanotic congenital heart lesions. In acyanotic CHD ventricular septal defects (VSDs) constitute 38.8% followed by AV canal defect 6.7%, patent ductus arteriosus (PDA) 3.6%. In cyanotic CHD tetralogy of Fallot (TOF) was the commonest lesion accounted for 28 (8.3%) followed by d-transposition of great arteries 16 (4.7%), pulmonary atresia 15 (4.5%), total anomalous pulmonary venous circulation TAPVC 11 (3.3%), tricuspid atresia 9 (2.7%) and DORV, VSD, PS 10 (2.9%). The commonest combination was VSD with ASD in 15 cases (4.5%). Most of the patient was diagnosed in 1st year of age 280 (83.1%)
Conclusions: CHD are very common in our setup and early detection of CHD is increasing. Overall burden of CHD is also increasing therefore a proper population-based study on a large scale is needed to estimate the prevalence accurately.
References
What are congenital heart defects? 2011. Available at: http://www.nhlbi.nih.gov/health/health-topics/ topics/chd/. Accessed on 15 August, 2023.
Thiene G, Fresura C. Anatomical and pathophysiological classification of congenital heart disease. Soc Cardiovasc Pathol. 2010;19(5):259-74.
Congenital heart defects: What causes congenital heart defects? 2014. Available at: http://www.ncbi.nlm.nih.gov/pubmedhealth/ PMH0062980/. Accessed on 15 August, 2023.
Razzaq AY, Bener L, Al-Gazali LI, Al-Khayat AI, Micallef R, Gaber T. A study of possible deleterious effects of consanguinity. Clin Genet. 1997;51(3):167-73.
Lorenzo D, Adolfo C. Decreasing the burden of congenital heart anomalies: an epidemiologic evaluation of risk factors and survival of congenital heart diseases. Progress in Pediatric Cardiol. 2003;18(2):111-21.
Linde D, Konings EEM, Slager MA, Witsenburg, M, Helbing WA, Takkenberg JJM, et al. Birth Prevalence of Congenital Heart Disease Worldwide a Systematic Review and Meta-analysis. J Am Coll Cardiol. 2011;58(21):2241-7.
Razzaque SK, Nahar S, Akhter S, Jahan N, Begum J. National Institute of Cardiovascular Diseases, congenital rubella, congenital heart disease and its prevention in the developing country like Bangladesh. Bangladesh Heart J. 2007;39(2):34.
Shermin LS, Hoque MA, lqbal M, Ayub M. Pattern and clinical profile of congenital heart disease in a teaching hospital, TAJ. 2008;21:58-62.
Roger VL, GO AS, Lloyd-Jones DM, Benjamin EJ, Berry JD, Borden WB et al. Heart disease and stroke statistics-2012 update a report from the American Heart Association. Circulation. 2012;125(1):e2-220.
Mollah MAH, Begum NA, Islam MN, Mahmud RS, Haq MA, Nahar N et al. Clinical Profile of Congenital Heart Diseases (CHD): An Analysis of 218 Cases. Bangladesh Heart J. 2002;17:62-67.
Hassan I, Haleem AA, Bhutta ZA. Profile and risk factors for congenital heart disease. J Pak Med Assoc. 1997;47(3):78-81.
Sharmin LS, Azizul Haque M, Bari MI, Ali MA. Pattern and Clinical Profile of Congenital Heart Disease in A Teaching Hospital. J Teachers Assoc. 2008;21(2):58-62.
Hoffman JIE. Incidence of congenital heart disease: I. Postnatal incidence. Pediatric Cardiol. 1995;16(3):103-13.
Malik A. Problems of Cardiovascular disease in Bangladesh and other developing country. Proceeding of the Bangladesh-Japan joint conference on CVD, Dhaka, Bangladesh. 1984.
Khalil A, Aggarwal R, Thirupuram S, Arora R. Incidence of congenital heart disease among hospital live births in India. Indian Pediatr. 1994;31(5):519-27.
Kapoor R, Gupta S. Prevalence of Congenital Heart Disease, Kanpur, India. Indian Pediatr. 2008;45:309-11.
Fyler DC, Buckley LP, Hellenbrand WE, Cohn HE. Report of the New England regional infant care program. Pediatrics. 1980;65(1):375-461.
Abdullah R. What is the prevalence of congenital heart disease? Ped Cardiol. 1997;18:268.
Hussain M, Amin SK, Moller MR. Pattem of Congenital Heart Disease in Dhaka Shishu Hospital. D S (Child) H J. 1992;8:35-46.
Burki MK, Babar GS. Prevalence and pattern of congenital heart disease in Hazara. J Ayub Med Coll Abbottabad. 2001;13(4):16-8.
Aman W, Sherin A, Hafizullah M. Frequency of Congenital Heart Diseases in Patients Under the Age of Twelve Years At Lady Reading Hospital Peshawar. JPMI. 2006;9(1):64-9.
Mogyorósy G, Belicza E, Karácsonyi T, Szúcs E. Incidence and invasive treatment of congenital heart diseases in Hajdu-Bihar-county. Orv Hetil. 2000;141(23):1287-92.
