Assessment of depression in diabetic patients
DOI:
https://doi.org/10.18203/2320-6012.ijrms20233161Keywords:
Depression, Diabetes, Hamilton score, AnxietyAbstract
Background: Diabetes is one of the most common chronic conditions in the world. The worldwide prevalence of diabetes mellitus (DM) has risen dramatically over the past two decades because of increasing obesity and reduced activity levels. The purpose of this study was to show the association between depression and diabetes.
Methods: It was a cross-study. The study included 240 patients who were chosen randomly with no gender bias. A convenient subject of 240 diabetic patients was interviewed.
Results: Out of the total 240 diabetic patients, included in this study, the majority of patients, 52.63% in the age group of 60 years had depression with a Hamilton score of >19 while 47.37% of patients in the age of 40 to 50 years had Hamilton score of >19. 84.21% of males had depression with a Hamilton score >19 as compared to females who had a Hamilton score of 15.79%. The patients within the age group of 40-59 have 2.5 times more risk of having depression as compared to the age group of 20 to 39 and patients in the age group >60 years have 4.23 times higher risk of depression as compared to patients in the age group of 20 to 39 years. The association between gender and depression shows that males have a higher rate of depression (78.17%) as compared to females (21.81%) with an odd's ratio of 3.0.
Conclusions: Our study showed a high prevalence of depression and anxiety in male patients and the elderly age group. Planning and implementation of screening for mental health issues in the elderly population diagnosed with a lifestyle disease-such as type 2 diabetes mellitus-with existing comorbidities should be recognized as one of the most important goals of the public health system. It seems necessary to involve medical teams in the screening process to verify the symptoms, promptly establish the diagnosis, and initiate the appropriate depression treatment. In diabetic patients, depression remains underdiagnosed and an important aspect of the diabetic specialists would be the awareness of this quite common co-morbidity.
References
International Diabetes Federation. IDF Diabetes Atlas. 9th edition. Brussels, Belgium: International Diabetes Federation. 2019.
Gujral UP, Narayan KM, Pradeepa RG, Deepa M, Ali MK, Anjana RM, et al. Comparing type 2 diabetes, prediabetes, and their associated risk factors in Asian Indians in India and the U.S: The CARRS and MASALA studies. Diabetes Care. 2015;38:1312-8.
Mohan V, Deepa M, Anjana RM, Lanthorn H, Deepa R. Incidence of diabetes and pre-diabetes in a selected urban south Indian population (CUPS-19). J Assoc Physicians India. 2008;56:152-7.
Bromet E, Andrade LH, Hwang I, Sampson NA, Alonso J, de GG, et al. Cross-national epidemiology of DSM-IV major depressive episode. BMC Med. 2011;9:90.
OECD. Making Mental Health Count: The Social and Economic Costs of Neglecting Mental Health Care. OECD Health Policy Studies. OECD Publishing, Paris. 2014.
National Institute of Health Metrics Evaluation. Global Burden of Disease. 2015. Available at: https://www.healthdata.org/research-analysis/gbd. Accessed on 13 August 2023.
Anderson RJ, Freedland KE, Clouse RE, Lustman PJ. The prevalence of comorbid depression in adults with diabetes: A meta‑analysis. Diabetes Care. 2001;24:1069‑78.
Hellman R. The Patient Safety Exchange. AACE Patient Safety –Editorials. Depression and Diabetes and Patient Safety. 2008;16:42:38.
Rubin RR, Ma Y, Marrero DG, Peyrot M, Barrett‑Connor EL, Kahn SE, et al. Elevated depression symptoms, antidepressant medicine use, and risk of developing diabetes during the diabetes prevention program. Diabetes Care. 2008;31:420‑6.
Katon W, Lin EH, Kroenke K. The association of depression and anxiety with medical symptom burden in patients with chronic medical illness. Gen Hosp Psychiatry. 2007;29:147‑55.
Lloyd CE, Dyer PH, Barnett AH. Prevalence of symptoms of depression and anxiety in a diabetes clinic population. Diabet Med. 2000;17:198‑202.
Gonzalez JS, Peyrot M, McCarl LA, Collins EM, Serpa L, Mimiaga MJ, et al. Depression and diabetes treatment nonadherence: a meta-analysis. Diabetes Care. 2008;31:2398-403.
Baumeister H, Hutter N, Bengel J, Harter M. Quality of life in medically ill persons with comorbid mental disorders: a systematic review and meta-analysis. Psychother Psychosom. 2011;80(5):275-86.
Berge LI, Riise T. Comorbidity between Type 2 Diabetes and Depression in the Adult Population: Directions of the Association and Its Possible Pathophysiological Mechanisms. Int J Endocrinol. 2015;80:275.
Moulton CD, Pickup JC, Ismail K. The link between depression and diabetes: the search for shared mechanisms. Lancet Diabetes Endocrinol. 2015;3:461-71.
Leone T, Coast E, Narayanan S, de Graft Aikins A. Diabetes and depression comorbidity and socio-economic status in low and middle-income countries (LMICs): a mapping of the evidence. Global Health. 2012;8:39.
Naranjo DM, Fisher L, Areán PA, Hessler D, Mullan J. Patients with type 2 diabetes at risk for major depressive disorders over time. Ann Fam Med. 2011;9:115-20.
Rajput R, Gehlawat P, Gehlan D, Gupta R, Rajput M. Prevalence and predictors of depression and anxiety in patients of diabetes mellitus in a tertiary care centre. Indian J Endocrinol Metab. 2016;20(6):746-51.
Mathur D, Anand A, Srivastava V, Patil SS, Singh A, Rajesh SK, et al. Depression in High-Risk Type 2 Diabetes Adults. Ann Neurosci. 2020;27(3-4):204-13.
Riise LIBT, Tell GS, Iversen MM, Østbye T, Lund A, Knudsen AK. Depression in Persons with Diabetes by Age and Antidiabetic Treatment: A Cross-Sectional Analysis with Data from the Hordaland Health Study. PLoS One. 2015;10(5):e0127161.