Prevalence, risk factors, causative organism and antibiotic susceptibility of catheter associated urinary tract infections

Rajesh Venkataraman; Gloriya Grifth Manuel; Jeevan Rai N.; Shahasanu R. S.; Akshay S. R.; Eldho Paul; Muhammed Sanib

doi:10.18203/2320-6012.ijrms20233997

Authors

Rajesh Venkataraman Department of Pharmacy Practice, Sri Adichunchanagiri College of Pharmacy, B. G. Nagara, Karnataka, India
Gloriya Grifth Manuel Department of Pharmacy Practice, Sri Adichunchanagiri College of Pharmacy, B. G. Nagara, Karnataka, India
Jeevan Rai N. Department of Pharmacy Practice, Sri Adichunchanagiri College of Pharmacy, B. G. Nagara, Karnataka, India
Shahasanu R. S. Department of Pharmacy Practice, Sri Adichunchanagiri College of Pharmacy, B. G. Nagara, Karnataka, India
Akshay S. R. Department of Pharmacy Practice, Sri Adichunchanagiri College of Pharmacy, B. G. Nagara, Karnataka, India
Eldho Paul Department of Pharmacy Practice, Sri Adichunchanagiri College of Pharmacy, B. G. Nagara, Karnataka, India
Muhammed Sanib Department of Pharmacy Practice, Sri Adichunchanagiri College of Pharmacy, B. G. Nagara, Karnataka, India

DOI:

https://doi.org/10.18203/2320-6012.ijrms20233997

Keywords:

Antimicrobial resistance, CAUTI, Nosocomial infections, UTI

Abstract

Background: The most common nosocomial infection is catheter-associated urinary tract infection (CAUTI), with a 3-7% daily risk of developing CAUTI in acute care settings. This study's goal was to identify the prevalence, risk factors, causative organism of CAUTI and understanding the organism's current antimicrobial agent sensitivity profile.

Methods: Total 120 patients participated in a prospective and observational study conducted at Adichunchanagiri Hospital, Karnataka. Reviewing and evaluating patient case sheets, laboratory results, and treatment charts of participants who were hospital inpatients provided data needed for the study. Microsoft Excel was used to enter the data and version 28 of SPSS to analyze the data. Statistical significance was determined by using a P-value of less than 0.05.

Results: It was discovered that 12.5% of HAI cases were linked to catheter use. The most prevalent microbial agent in the current investigation was E. coli (41.7%). According to the current study, women are more likely than men to get UTIs. An underlying medical condition was found to have a strong correlation with UTIs in the current investigation. For CAUTI, drug resistance to cefotaxime and tigecycline was noted.

Conclusions: The study suggested that gender, age extremes, use of antibiotics, length of stay in intensive care unit, diabetes mellitus, immunosuppressive medication, and indwelling urinary devices are the major risk factors for CAUTI. E. coli was the most common microbiological agent in the current study. Therefore, to assist doctors in the treatment and management of CAUTIs, ongoing surveillance of antimicrobial resistance patterns is required.

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