Exploring typical and atypical variants of celiac disease: a narrative review

Yugam R. Oza; Hussein Abdikadir Hassan; Helly Mayankkumar Joshi; Aisha Siddiqui; Farina Fartima Siddiqui; Muhammad Hamza Gul

doi:10.18203/2320-6012.ijrms20234028

Authors

Yugam R. Oza Department of Medicine, Grodno State Medical University, Belarus
Hussein Abdikadir Hassan Department of Medicine, Grodno State Medical University, Belarus
Helly Mayankkumar Joshi Department of Medicine, Grodno State Medical University, Belarus
Aisha Siddiqui Department of Medicine, Liaquat University of Medical Health and Science, Jamshoro
Farina Fartima Siddiqui Department of Medicine, Liaquat University of Medical Health and Science, Jamshoro
Muhammad Hamza Gul Bacha Khan Medical College, Mardan

DOI:

https://doi.org/10.18203/2320-6012.ijrms20234028

Keywords:

Atypical celiac disease, Extra intestinal celiac disease, Celiac disease, Gluten free diet, Typical celiac disease

Abstract

There are many different clinical manifestations of celiac disease (CD), including the classical form, in which intestinal symptomatology predominates on the contrary there is atypical forms, in which extra-intestinal clinical features predominate, and the silent form, in which there are no clinical symptoms. Few or no gastrointestinal symptoms and a predominance of extra-intestinal features, including liver, kidney, skeletal, psychiatric, neurologic, dermatologic, hematologic, endocrinological, and reproductive involvements, define the atypical forms of the disease. Through screening high-risk groups, silent presentations of CD may be found. It is crucial for healthcare professionals to have a high level of suspicion for the atypical presentations of CD because it is now well known that CD may account for a number of chronic health issues.

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