A rare prostatic tumour masquerading clinically as benign prostatic hyperplasia

Authors

  • Vinay S. Kundargi Department of Urology, Shri B. M. Patil Medical College Hospital and Research Centre, Vijayapura Karnataka, India
  • Siddanagouda B. Patil Department of Urology, Shri B. M. Patil Medical College Hospital and Research Centre, Vijayapura Karnataka, India
  • Santosh R. Patil Department of Urology, Shri B. M. Patil Medical College Hospital and Research Centre, Vijayapura Karnataka, India
  • Vikas Shukla Department of Urology, Shri B. M. Patil Medical College Hospital and Research Centre, Vijayapura Karnataka, India

DOI:

https://doi.org/10.18203/2320-6012.ijrms20241575

Keywords:

Inflammatory myofibroblastic prostate tumours, Prostatic tumour, Pseudotumour of the prostate

Abstract

Prostatic tumours are usually benign. Malignant tumours are usually adenocarcinoma. Rare benign prostate tumours include inflammatory myofibroblastic tumours, which can be found in various body parts and are frequently identified in the lung or abdominal cavity of children and young adults. Inflammatory myofibroblastic tumours of the urinary tract present more often in kidneys. Prostatic inflammatory myofibroblastic tumours are sporadic and rare. Presenting 44 years old male with complaints of gross hematuria for 15 days with recurrent urine retention. Per rectal examination revealed, grade II prostate enlargement was firm in consistency. PSA was mildly raised (4.4 ng/ml). Ultrasound abdomen showed enlarged prostate (volume -40 cc) with irregular margins and heterogeneous echo texture showing increased flow on colour Doppler. Transrectal ultrasound (TRUS) showed a well-defined irregular heterogeneously echoic mass in the transitional zone, but TRUS biopsy showed no malignancy. After TURP, prostate chip examination showed inflammatory myofibroblastic pseudotumour of the prostate. Differentiation of inflammatory myofibroblastic prostate tumours from malignant tumours through imaging and laboratory tests is difficult. A case of prostatic inflammatory myofibroblastic tumour observed after transurethral resection of the prostate to treat prostate hyperplasia in a 44-year-old man is presented in this report.

 

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References

Janik JS, Janik JP, Lovell MA, Hendrickson RJ, Bensard DD, Greffe BS. Recurrent inflammatory pseudotu- mors in children. J Pediatr Surg, 2003;38(10):1491-952.

Roth JA. Reactive pseudosarcomatous response in urinary bladder. Urology. 1980;16(6):635-7.

Hafiz MA, Toker C, Sutula M. An atypical fibromyxoid tumor of the prostate. Cancer. 1984;54(11):2500-4.

Ro JY, Ayala AG, Ordonez NG, Swanson DA, Babaian RJ. Pseudosarcomatous fibromyxoid tumor of the urinary bladder. Am J Clin Pathol. 1986;86(6):583-90.

Ro JY, El-Naggar AK, Amin MB, Sahin AA, Ordonez NG, Ayala AG. Pseudosarcomatous fibromyxoid tumor of the urinary bladder and prostate: immunohistochemical, ultrastructural, and DNA flow cytometric analyses of nine cases. Hum Pathol. 1993;24(11):1203-10.

Horn LC, Reuter S, Biesold M. Inflammatory pseudotumor of the ureter and the urinary bladder. Pathol. Res Pract. 1997;193(9):607-12.

Guillou L, Costa J. Postoperative pseudosarcomas of the genitourinary tract. A diagnostic trap. Presentation of 4 cases of which 2 were studied immunohistochemically and review of the literature. Ann Pathol. 1989;9(5):340-45.

Young RH, Scully RE. Pseudosarcomatous lesions of the urinary bladder, prostate gland, and urethra. A report of three cases and review of the literature. Arch Pathol Lab Med. 1987;111(4):354-8.

Tsuzuki T, Magi-Galluzzi C, Epstein JI. ALK-1 expression in inflammatory myofibroblastic tumor of the urinary bladder. Am J Surg Pathol. 2004;28(12):1609-14.

Morris SW, Kirstein MN, Valentine MB, Dittmer KG, Shapiro DN, Saltman DL, et al. Fusion of a kinase gene, ALK, to a nucleolar protein gene, NPM, in non-Hodgkin’s lymphoma. Science. 1994;263(5151):1281-4.

Proppe KH, Scully RE, Rosai J. Postoperative spindle cell nodules of genitourinary tract resembling sarcomas. A report of eight cases. Am J Surg Pathol. 1984;8(2):101-8.

Jensen KB, Langkilde NC, Lundbeck F, Marcussen N. Pseudosarcomatous fibromyxoid tumor of the prostate. Scand J Urol Nephrol. 2003;37(1):85-7.

Harik LR, Merino C, Coindre JM, Amin MB, Pedeutour F, Weiss SW. Pseudosarcomatous myofibroblastic proliferations of the bladder. A clinicopathologic study of 42 cases. Am J Surg Pathol. 2006;30(7):787-94.

Atis G, Gurbuz C, Kiremit MC, Guner B, Zemheri E, Caskurlu T. Pseudosarcomatous Fibromyxoid Tumor of the Prostate. Scientific World J. 2011;11:1027-30.

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Published

2024-05-31

How to Cite

Kundargi, V. S., Patil, S. B., Patil, S. R., & Shukla, V. (2024). A rare prostatic tumour masquerading clinically as benign prostatic hyperplasia. International Journal of Research in Medical Sciences, 12(6), 2133–2136. https://doi.org/10.18203/2320-6012.ijrms20241575

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Section

Case Reports