Multiple unilateral craniopathies (Guillain-Alajouanine-Garcin syndrome) resulting from a malignancy of the external auditory canal: a case report

Kevin Royce G. Ang; Ceferino L. Rivera; Francis A. Almelor

doi:10.18203/2320-6012.ijrms20240543

Authors

Kevin Royce G. Ang Department of Neurosciences, East Avenue Medical Center, Quezon City, Philippines
Ceferino L. Rivera Department of Neurosciences, East Avenue Medical Center, Quezon City, Philippines
Francis A. Almelor Department of Neurosciences, East Avenue Medical Center, Quezon City, Philippines

DOI:

https://doi.org/10.18203/2320-6012.ijrms20240543

Keywords:

Garcin syndrome, Multiple craniopathies, External auditory canal malignancy

Abstract

Garcin syndrome (or Gullain-Alajouanine-Garcin syndrome) was first described in the year 1926, as a paralytic unilateral cranial syndrome consisting of multiple cranial nerve palsies, without findings pointing towards increased intracranial pressure or long tract involvement. A 54-year-old female presented to us initially with ptosis and lateral rectus palsy of the right eye, later on, followed by progressive hearing loss on the right ear, right facial hemianesthesia, and progressive ipsilateral facial paralysis. A mass at the external auditory canal was seen during otoscopy, and a biopsy revealed squamous cell carcinoma. Contrast-enhanced neuroimaging also showed an enhancing mass lesion at the right skull base.

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