Characteristics of intracranial atherosclerosis disease in stroke cases in Indonesia utilizing cerebral digital subtraction angiography

Fritz S. Usman; Merlin P. Kastilong; David Susanto; Muhammad Welly Dafif; Gomgom Henrico Sirait

doi:10.18203/2320-6012.ijrms20240826

Authors

Fritz S. Usman Departement of Interventional Neurology, Pelni Hospital, West Jakarta, Indonesia
Merlin P. Kastilong Departement of Interventional Neurology, Pelni Hospital, West Jakarta, Indonesia
David Susanto Departement of Interventional Neurology, Pelni Hospital, West Jakarta, Indonesia
Muhammad Welly Dafif Department of Neurology, Ulin General Hospital, Banjarmasin, Indonesia
Gomgom Henrico Sirait Department of Neurology, Doris Sylvanus Hospital, Palangka Raya, Indonesia

DOI:

https://doi.org/10.18203/2320-6012.ijrms20240826

Keywords:

Cerebral digital subtraction angiography, Intracranial atherosclerotic disease, Stroke recurrence

Abstract

Background: Intracranial atherosclerosis disease is a cause of ischemic stroke. Risk factors of ICAD included age, gender, race/ethnicity, hypertension, diabetes mellitus, and dyslipidaemia. This study aimed to describe the profile of ICAD in first-ever stroke and its association of recurrent stroke.

Methods: The was a prospective cohort study conducted at a private hospital in Indonesia between January 2021 and June 2022. Inclusion criteria included patients with first-ever stroke and intracranial stenosis confirmed through digital subtraction angiography. The incidence of recurrent stroke was observed at six-month follow-up.

Results: Of 40 subjects, 25 (62.5%) were females and most ages ranged from 20 to 40 years old. The prevalent site of intracranial stenosis were internal carotid artery in 19 (23.2%) and anterior cerebral artery in 19 (23.2%) subjects. Following six-month follow-up, there was only a patient with recurrent stroke.

Conclusions: In first-ever stroke in Indonesia, ICAD was predominantly described in younger men within 41-60 years old. Stroke recurrence was observed in a patient who was old and had multiple comorbid. Further studies using a larger area and longer duration of follow-up may be considered to provide a more generalized description of ICAD in Indonesia.

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