Aggressive salivary duct carcinoma with widespread dissemination: a case report

Authors

  • Anindita Saha Department of Oral Medicine and Radiology, Burdwan Dental College and Hospital, Burdwan, West Bengal, India
  • Sailendranath Biswas Department of Oral Medicine and Radiology, Burdwan Dental College and Hospital, Burdwan, West Bengal, India
  • Asish K. Das Department of Oral and Maxillofacial Surgery, Dr. R. Ahmed Dental College and Hospital, Kolkata, West Bengal, India
  • Shreya Ganguly Department of Oral and Maxillofacial Surgery, Dr. R. Ahmed Dental College and Hospital, Kolkata, West Bengal, India

DOI:

https://doi.org/10.18203/2320-6012.ijrms20240312

Keywords:

Neoplasm metastasis, Salivary gland neoplasm

Abstract

Salivary duct carcinoma is a rare and aggressive salivary gland malignancy with a poor prognosis. Due to the paucity of literature, very little is known about this neoplasm. We have described such a case in this case report and highlighted the clinical and histopathological features associated with this disease. A sixty-year old male patient reported in the outpatient department of a regional dental college and hospital with a circular firm growth in the mandibular anterior region and mobility of adjacent mandibular teeth. An array of investigations including radiographic, tomographic, ultrasonographic as well as histopathological were performed. It was diagnosed as invasive salivary duct carcinoma with distant metastases in the shoulder joint, ribs as well as pelvic bones. Currently, no National Comprehensive Cancer Network guidelines for the specific treatment of salivary duct carcinomas exist. National Comprehensive Cancer Network guidelines recommend complete surgical excision of tumors for major salivary gland tumors without nodal involvement (N0) with or without neck dissection for high-grade and T3/T4 salivary gland tumors.

 

References

Anwer AW, Faisal M, Adeel M, Waqas O, Abu Bakar M, Qadeer S, et al. Clinicopathological Behavior and Treatment-related Outcome of Rare Salivary Duct Carcinoma: The Shaukat Khanum Memorial Cancer Hospital Experience. Cureus. 2018;10(8):e3139.

Hsu CC, Li WY, Chu PY. Salivary duct carcinoma of the supraglottis with a distinct presentation. A case report and literature review. Medicine (Baltimore). 2018;97(11):e0095.

Adeberg S, Windisch P, Ehret F, Baur M, Akbaba S, Held T, et al. Intensity Modulated Radiotherapy (IMRT) With Carbon Ion Boost in the Multimodal Treatment of Salivary Duct Carcinoma. Front Oncol. 2019;9:1420.

Simpson RH. Salivary duct carcinoma: new developments--morphological variants including pure in situ high grade lesions; proposed molecular classification. Head Neck Pathol. 2013;7(1):S48-58.

Kleinsasser O, Klein HJ, Hübner G. Speichelgangearcinome. Salivary duct carcinoma. A group of salivary gland tumors analogous to mammary duct carcinoma. Arch Klin Exp Ohren Nasen Kehlkopfheilkd. 1968;192(1):100-5.

Johnston ML, Huang SH, Waldron JN, Atenafu EG, Chan K, Cummings BJ, et al. Salivary duct carcinoma: Treatment, outcomes, and patterns of failure. Head Neck. 2016;38(1):E820-6.

Stodulski D, Mikaszewski B, Majewska H, Kuczkowski J. Parotid salivary duct carcinoma: a single institution's 20-year experience. Eur Arch Otorhinolaryngol. 2019;276(7):2031-8.

Jaehne M, Roeser K, Jaekel T, Schepers JD, Albert N, Löning T. Clinical and immunohistologic typing of salivary duct carcinoma: a report of 50 cases. Cancer. 2005;103(12):2526-33.

Nakaguro M, Tada Y, Faquin WC, Sadow PM, Wirth LJ, Nagao T. Salivary duct carcinoma: Updates in histology, cytology, molecular biology, and treatment. Cancer Cytopathol. 2020;128(10):693-703.

Downloads

Published

2024-02-08

How to Cite

Saha, A., Biswas, S., Das, A. K., & Ganguly, S. (2024). Aggressive salivary duct carcinoma with widespread dissemination: a case report. International Journal of Research in Medical Sciences, 12(3), 958–961. https://doi.org/10.18203/2320-6012.ijrms20240312

Issue

Section

Case Reports