Significance of calcium: its correlation with red and white muscle contraction, fatigue and potential

Alejandra A. Castro; Mariano B. L. Perez; Guillermo A. Gonzalez; Natalia C. Bonilla; Gerardo G. Santiago; Ishmeet Singh

doi:10.18203/2320-6012.ijrms20240691

Authors

Alejandra A. Castro Department of Academic Unit of Health Sciences, Universidad Autonoma de Guadalajara, Guadalajara, Jalisco, Mexico
Mariano B. L. Perez Department of Academic Unit of Health Sciences, Universidad Autonoma de Guadalajara, Guadalajara, Jalisco, Mexico
Guillermo A. Gonzalez Department of Academic Unit of Health Sciences, Universidad Autonoma de Guadalajara, Guadalajara, Jalisco, Mexico https://orcid.org/0009-0001-8356-9096
Natalia C. Bonilla Department of Internal Medicine, Hospital Regional Valentin Gomez Farias Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado, Zapopan, Jalisco, Mexico https://orcid.org/0009-0000-2416-2387
Gerardo G. Santiago Department of Academic Unit of Health Sciences, Universidad Autonoma de Guadalajara, Guadalajara, Jalisco, Mexico https://orcid.org/0009-0009-9135-400X
Ishmeet Singh Department of Science, Stockdale High School, Bakersfield, California, United States

DOI:

https://doi.org/10.18203/2320-6012.ijrms20240691

Keywords:

Contraction, Muscle, Neuromuscular junction, Calcium, Fatigue, Correlation between muscle types

Abstract

According to the predominant types of muscle fibers in an individual, they will have the ability to perform different types of exercises (both aerobic and anaerobic). To comprehend the mechanism of muscle fibers, which can act in diverse ways, enhancing either resistance or power, it is essential to examine the significance of calcium. Calcium plays a crucial role in both red and white muscle fibers. The release of calcium in white (fast-twitch) muscle fibers is significantly greater and faster, resulting in increased energy consumption, facilitating explosive physical activities. Conversely, in red (slow-twitch) muscle fibers, the release of calcium occurs in smaller amounts and over a prolonged period, leading to sustained energy consumption. The characteristics of contraction in red fibers enable endurance activities. A reduction in the amount of calcium results in diminished muscle contractile capacity, known as fatigue. The primary contributing factor, as previously mentioned, is the decline in calcium, but factors such as lactic acid and the dephosphorylation of the myosin head also contribute to its onset.

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