Psychosocial correlates of depression in paediatric patients with epilepsy in a teaching hospital in Nigeria

Authors

  • Nonyenim Solomon Enyidah Department of Medicine, College of Health Sciences, Rivers State University, Port Harcourt, Nigeria
  • Chidubem Onyema Abazie Department of Mental Health/Psychiatry, University of Port Harcourt Teaching Hospital (UPTH), Port Harcourt, Rivers State, Nigeria
  • Esther Ijeoma Nonye-Enyidah Department of Obstetrics and Gynaecology, Rivers State University Teaching Hospital, Port Harcourt, Nigeria

DOI:

https://doi.org/10.18203/2320-6012.ijrms20241224

Keywords:

CES-DC, DICA-IV, Epilepsy, Paediatrics, Psychosocial variables

Abstract

Background: Seizures are the most common paediatric neurological disorder with most children suffering at least one seizure before the age 16yr. The psychosocial comorbidities which adversely affect quality of life especially depression, are often neglected. This study sorts to highlight the psychosocial correlates of depression among these children.

Methods: Recruitment was in a paediatric neurology clinic in a tertiary-level hospital. Children were eligible for recruitment if aged 9-18 and had a diagnosis of epilepsy as confirmed by a neurologist, in care for a period of more than 3 months, and parents gave consent. Children who met the study inclusion criteria were subjected to a two- stage interview process using CES and DICA-1V tools, designed to screen and confirm depression. These instruments have previously been validated on a Nigerian population. The study was cross section and descriptive, with psychometric evaluation p-values<0.05, statistically significant.

Results: A total of 400 children were offered participation, and 380 were recruited, among them, 117 (30.8%) met the clinical criteria for major depression with 40 (10%) of them in need of urgent medical attention. Males were more depressed, p=0.000, OR: 0.861, respondents aged 9-11yr showed a strong association with depression p=0.001, OR: 1.911. Living arrangements of patients, p=0.001, OR: 0.632, family size (siblings), p=0.004, marital status of mothers, p=0.001, OR: 2.373, turned out significant with mothers’ marital status showing a strong association. Duration of illness and frequency of seizures, showed a very strong association with depression p=0.023, OR:1.203, and p=0.001, OR:1.411 respectively.

Conclusions: The study highlights a strong association between effects of epilepsy and psychosocial wellbeing of children and the high risk posed by unstable family settings on children’s health.

References

Hee-Yeon Choi, Song E. Kim, Hyang Woon-Lee, Eui-Jing Kim. Social behavioural problems and the health-related quality of life in children and adolescents with epilepsy. Psych Investig. 2016;13(5):488-95.

Seyfhashemi M, Bahadoran P. Depression in children and adolescents with epilepsy: a 15 year research review of prevalence, and demographic and seizure related correlates. Iran J Pediatr. 2013;23(1):1.

Kanner AM, Dunn D. Diagnosis and management of depression and psychosis in children and adolescents with epilepsy. J. Child Neurol. 2014;9(1):565-72.

Abazie OC, Enyidah NS, Sternley P. Depression in children with epilepsy in a teaching hospital South-South Nigeria. Int Neuropsy Dis J. 2023;20(3):1-8.

Forsgreen L. Incidence and Prevalence. In: Wallace SJ. Ferrell K. eds. Epilepsy in Children. 2nd ed. London: Arnold; 2004:21-25.

Nuhu FT, Yusuf AJ, Lasisi MD, Aremu SB. Emotional distress among people with epilepsy in Kaduna, Northern Nigeria. Ann Trop Medi Publ Health. 2013;6(1).

Ogunrin Olubunmi A. Epilepsy in Nigeria-a review of etiology; epidemiology and management. Benin J. Postgrad. Med. 2006:27-51.

Ogunlesi T, Ogundeyi M, Olowu A. Pattern of childhood epilepsies in Sagumu, Nigeria. Ind J Pediatr. 2009;76:385-9.

Bakare MO, Omigbodun OO, Kuteyi OB, Meremikwu MM, Agomoh AO. Psychological complications of childhood chronic physical illness in Nigerian children and their mothers: the implication for developing pediatric liaison services. Chil Adolesc Psych Mental Health. 200;2:1-9.

Ronen GM, Streiner DL, Boyle MH, Cunningham CE, Lach L, Verhey LH, et al. Outcome trajectories in children with epilepsy; hypothesis and methodology of a Canadian longitudinal observational study. Pediatr. Neurol. 2014;50(1):38-48.

Ogun OC, Gbiri CA, Akinola OA, Ajirotutu OP, Fasesan AO, Oye AO. Psychosocial correlates of depression of depression in children and adolescents with epilepsy in a Nigerian neuropsychiatric hospital. J Clin Case Rep. 2012;2(152):2.

Adewuyo AO, Ola BA. Prevalence and risk factors for anxiety and depressive disorders in Nigerian adolescents with epilepsy. Epil Behav. 2005;6(34):342-7.

Turkey A, Beavis JM, Thaper AK, Kerr MP. Psychopathology in children and adolescents with epilepsy; an investigation of Predictive variables. Epilepsy Behav. 2008;12(1):136-44.

Akinsulore A, Adewuya A. Psychosocial aspect of Epilepsy in Nigeria; A review. Afr J Psych. 2010;13(5):351-6.

Nnajekwu CO, Nnajekwu UC, Ikefuna NA, Ojinnaka CN. Mental Health of Adolescents with Epilepsy in Enugu Nigeria; A cross sectional study. J Child Neurol. 2020;30(2):116-22.

Al Kiyumi H, Al-Huseini S, Mirza H, Al Balushi N, Al-Risi K, Al Toubi A, et al. Depressive symptoms and its correlate among children with epilepsy at Single-center Study in Oman. Oman Med J. 2021;36(6):e329.

Hesdorffer DC, Ishihara L, Mynepalli L, Webb DJ, Weil J, Hauser WA. Epilepsy, suicidelity and psychiatric disorders; a bidirectional association. Ann. Neurol. 2012;72(2):184-91.

Shehata N, Saleh SM, Kamal AM, Awad OK. Assessment of the frequency of depressive symptoms in epileptic children (Single Center Study). Risk Manag Healthc Poli. 2021;14:2089-97.

Thome-Souza S, Kuczynski E, Assumpção Jr F, Rzezak P, Fuentes D, Fiore L, et al. Which factors may play a pivotal role on determining the type of psychiatric disorder in children and adolescents with epilepsy?. Epil Behavi. 2004;5(6):988-94.

Faulstich ME, Carey MP, Ruggiero L. Enyari P, Gresham F. Assessment of depression in childhood and adolescents; an evaluation of the Centre for Epidemiological Studies Depression Scale for Children (CES-DC). Am J Psych. 1986;143(8):1024-7.

Lenore Sawyer Radloff. The CES-D Scale. A Self report depression scale for research in the general population. Appl Psycholog Meas. 1977;1(3):385-401.

Fendrich M, Weissman MM, Warner V. Screening for depressive disorders in children and adolescents. validating the centre for epidemiological studies depression scale for children. Ame J Epidemiol. 1990;131(3):583-51.

Shaffer D, Fisher P, Lucas CP, Dulcan MK, Schwab-Stone ME. NIMH Diagnostic Interview Schedule for Children Version IV (NINH DISC-IV) for Depression, Differences from previous versions, and reliability of some common diagnoses. J Ame Acad Chi Adolesc Psych. 2000;39(1):28-38.

Adewuya A, Ola B. Prevalence of risk factors for anxiety and depressive symptoms in Nigerian adolescents with epilepsy. Epil Behav. 2005;6:342-7.

Akinsulore A, Adewuya A. Psychosocial aspects of epilepsy in Nigeria. A review. Afr J. 2010;13(5):351-6.

Dunn DN, Austin JK, Huster GA. Symptoms of depression in adolescents with depression. J Am Acad Child Adolsc Psych. 1999;38(9):1132-8.

Seid J, Mebrahtu K. Prevalence and associated factors of depression among people with epilepsy in Ethiopia: a cross-sectional study. Egypt J Neurol Psych Neurosurg. 2022;58(1):105.

Hersha GT, Rajesh Raman, Ravi MD, TSS Rao. A study to assess the magnitude of depression on children and adolescents with epilepsy. Int J Clin Psych. 2018;6(3):49-51.

AES. Correlates of Depressive Symptoms in Adolescents with Depression in the Seizures and outcome Study, American Epilepsy Society, 2016. Available at: www. Aesnet.org. Accessed on 27 February 2024.

Stores G. School‐children with epilepsy at risk for learning and behaviour problems. Developm Medi Chi Neurol. 1978;20(4):502-8.

Bilgic A, Velmaz S, Tira S, Deda G, Kilic EZ. Depression and Anxiety Severity in a group of Children with Epilepsy and related factors. Turk Psikiyatri Derg. 2006;17(3):165-72.

Yang C, Hao Z, Mao Y, Xu Q, Zhao L, Zhang LL. Depression in children with epilepsy from western China: a cross-sectional survey. Medi. 2020;99(24):e20647.

Kanner AM, Balabanov A. Depression and epilepsy: how closely related are they?. Neurol. 2002;58(8_suppl_5):S27-39.

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Published

2024-04-30

How to Cite

Enyidah, N. S., Abazie, C. O., & Nonye-Enyidah, E. I. (2024). Psychosocial correlates of depression in paediatric patients with epilepsy in a teaching hospital in Nigeria. International Journal of Research in Medical Sciences, 12(5), 1438–1444. https://doi.org/10.18203/2320-6012.ijrms20241224

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Original Research Articles