A systematic review of clinical applications and diagnostic efficacy of intravascular optical coherence tomography in cardiology

Vanessa Marisol Almeida Sacoto; Ana Paula Coronel Mite; Washington Javier Masapanta Pilatasig; Rafael Andres Mosquera-Ceprian; Edith Viviana Muñoz Cunduri; Angelica Marina Basantes Castillo; Víctor Manuel Polo Roldán; Juan José Martínez Saltos; Jorge Andres Rivera Barzallo; Santiago Israel Cárdenas  Herrera

doi:10.18203/2320-6012.ijrms20241256

Authors

Vanessa Marisol Almeida Sacoto Specialist in Imagenology, Clínica Guayaquil, Ecuador https://orcid.org/0009-0004-7276-1156
Ana Paula Coronel Mite Medicine Department, Universidad Católica Santiago de Guayaquil, Ecuador https://orcid.org/0009-0005-2435-5492
Washington Javier Masapanta Pilatasig Emergency Medicine, Consultorio Médico Virgen le las Mercedes, Ecuador https://orcid.org/0009-0000-1109-7985
Rafael Andres Mosquera-Ceprian Medicine Department, Universidad Católica Santiago de Guayaquil, Ecuador https://orcid.org/0009-0002-9626-3173
Edith Viviana Muñoz Cunduri Medicine Department, Ministerio de Salud Pública, Ecuador https://orcid.org/0009-0005-9506-0034
Angelica Marina Basantes Castillo Medicine Department, Ministerio de Salud Pública, Ecuador https://orcid.org/0009-0002-5543-1281
Víctor Manuel Polo Roldán Medicine Department, Ministerio de Salud Pública, Ecuador https://orcid.org/0009-0005-3808-1840
Juan José Martínez Saltos Medicine Department, Ministerio de Salud Pública, Ecuador https://orcid.org/0009-0000-8056-7602
Jorge Andres Rivera Barzallo Medicine Department, Ministerio de Salud Pública, Ecuador https://orcid.org/0009-0006-7355-1876
Santiago Israel Cárdenas Herrera Medicine Department, Independent Investigator, Ecuador https://orcid.org/0009-0001-1648-3196

DOI:

https://doi.org/10.18203/2320-6012.ijrms20241256

Keywords:

Intravascular optical coherence tomography, Cardiology, Systematic review

Abstract

Intravascular Optical Coherence Tomography (OCT) has emerged advanced imaging modality in cardiology, offering high-resolution visualization of coronary artery structures. Since its inception in the late 1990s, OCT has undergone significant advancements, transitioning from time-domain to frequency-domain systems, thereby enhancing its clinical viability and diagnostic efficacy. We aimed to comprehensively assess the clinical applications and diagnostic efficacy of intravascular OCT in cardiology, particularly in guiding percutaneous coronary interventions (PCI) and evaluating coronary artery diseases. In methodology, A systematic search was conducted in PubMed and Google Scholar databases for studies published between 2013 and 2023, comparing OCT with intravascular ultrasound (IVUS) and conventional angiography (C.A.) in guiding PCI procedures. Studies were selected based on predefined inclusion and exclusion criteria, focusing on major adverse cardiovascular events (MACE), cardiac death, and revascularizations as outcomes. In results we included 28 studies from databased and 3 manuals, highlighting OCT's superior resolution in identifying thin-capped fibroatheromas (TCFAs), optimizing stent placement, and assessing plaque composition. Comparative analyses revealed no significant differences in clinical efficacy between OCT and IVUS, with both modalities showing superiority over C.A. in reducing cardiovascular events. The OCTIVUS trial further confirmed the non-inferiority of OCT-guided PCI compared to IVUS-guided PCI, with lower procedural complications reported in the OCT group. In conclusion, Intravascular OCT has revolutionized the diagnostic and interventional landscape in cardiology, offering unparalleled insights into coronary artery pathology. Its high-resolution imaging capabilities facilitate accurate plaque characterization, stent optimization, and real-time intervention guidance, thereby improving clinical outcomes in PCI procedures. Future research should focus on expanding OCT's applications and further validating its efficacy in diverse clinical settings.

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References

Yonetsu T, Jang I. Cardiac optical coherence tomography. JACC Asia. 2023.

Park DY, An S, Jolly N, Attanasio S, Yadav N, Gutiérrez J, et al. Comparison of intravascular ultrasound, optical coherence tomography, and conventional angiography-guided percutaneous coronary interventions: A systematic review, network meta-analysis, and meta-regression. Catheter Cardiovasc Interv. 2023;102(3):440-50.

Roland R, Veselka J. Optical coherence tomography of the coronary arteries. Int J Angiol. 2021;30(01):29-39.

Kume T, Uemura S. Current clinical applications of coronary optical coherence tomography. Cardiovasc Interv Ther. 2017;33(1):1-10.

Vignali L, Solinas E, Emanuele E. Research and clinical applications of optical coherence tomography in invasive cardiology: a review. Curr Cardiol Rev. 2014;10(4):369-76.

Kang D, Ahn J, Yun S, Hur S, Cho Y, Lee CH, et al. Optical coherence tomography-guided or intravascular ultrasound-guided percutaneous coronary intervention: the OCTIVUS randomized clinical trial. Circulation. 2023;148(16):1195-206.

Wang J, Yuan S, Qi J, Zhang Q, Ji Z. Advantages and prospects of optical coherence tomography in interventional therapy of coronary heart disease (Review). Exp Ther Med. 2022;23(4).

Jorge E, Baptista R, Calisto J, Faria H, Monteiro P, Pan M, et al. Optical coherence tomography of the pulmonary arteries: a systematic review. J Cardiol. 2016;67(1):6-14.

Oosterveer TTM, Meer SM, Scherptong RW, Jukema JW. Optical coherence tomography: current applications for the assessment of coronary artery disease and guidance of percutaneous coronary interventions. Cardiol Ther. 2020;9(2):307-21.

Okamoto H, Kume T, Nishi T, Koto S, Sasahira Y, Yamada R, et al. Efficacy of optical coherence tomography-guided primary percutaneous coronary intervention in patients with acute coronary syndrome. Acta Cardinol Sin. 2023;39(2):266-76.

News-Medical. Study shows efficacy and safety of OCT-guided strategy for percutaneous coronary intervention, 2023. Available at: https://www.news-medical.net/news/20230828/Study-shows-efficacy-and-safety-of-OCT-guided-strategy-for-percutaneous-coronary-intervention.aspx. Accessed on 15 March 2024.

Roland R, Veselka J. Optical coherence tomography of the coronary arteries. Int J Angiol. 2021;30(1):29-39.

Roleder T, Jąkała J, Kałuża GL, Partyka Ł, Proniewska K, Pociask E, et al. The basics of intravascular optical coherence tomography. Postępy W Kardiologii Interwencyjnej. 2015;2:74-83.

Ughi GJ, Adriaenssens T. Intracoronary optical coherence tomography. Computing and visualization for intravascular imaging and computer-assisted stenting. JACC Cardiovasc Interv. 2017;10(24):2473-87.

DiVito L, Yoon JH, Kato K, Yonetsu T, Vergallo R, Costa M, et al. Comprehensive overview of definitions for optical coherence tomography-based plaque and stent analyses. Coron Artery Dis. 2014;25(2):172-85.

Sharma U, Chang EW, Yun SH. Long-wavelength optical coherence tomography at 17 μm for enhanced imaging depth. Opt Express. 2008;16(24):19712.

Terashima M, Kaneda H, Suzuki T. The role of Optical coherence tomography in coronary Intervention. Korean J Intern Med. 2012;27(1):1.

Roleder T, Jąkała J, Kałuża GL, Partyka Ł, Proniewska K, Pociask E, et al. The basics of intravascular optical coherence tomography. Postępy W Kardiologii Interwencyjnej. 2015;2:74-83.

Honda Y, Fitzgerald PJ. Frontiers in intravascular imaging technologies. Circulation. 2008;117(15):2024-37.

Matthews SD, Frishman WH. A review of the clinical utility of intravascular ultrasound and optical coherence tomography in assessing and treating coronary artery disease. Cardiol Rev. 2017;25(2):68-76.

Li J, Shang C, Rong Y, Sun J, Cheng Y, He B, et al. Review on Laser Technology in intravascular imaging and treatment. Aging Dis. 2022;13(1):246.

Chamié D, Wang Z, Bezerra H, Rollins AM, Costa MA. Optical coherence tomography and fibrous cap characterization. Curr Cardiovasc Imaging Rep. 2011;4:276-83.

Bouma BE, de Boer JF, Huang D, Jang IK, Yonetsu T, Leggett CL, et al. Optical coherence tomography. Nat Rev Methods Primers. 2022;2(1):79.

Yin Y, He C, Xu B, Li Z. Coronary plaque characterization from optical coherence tomography imaging with a two-pathway cascade convolutional neural network architecture. Front Cardiovasc Med. 2021;8:670502.

Subban V, Raffel O. Optical coherence tomography: fundamentals and clinical utility. Cardiovasc Diagn Ther. 2020;10(5):1389-414.

Pradhan A, Saran M, Vishwakarma P, Sethi R. Optical coherence tomography in in-stent restenosis: A challenge made easier. Heart Views. 2019;20(1):28.

Gupta A, Shrivastava A, Vijayvergiya R, Chhikara S, Datta RΚ, Aziz A, et al. Optical Coherence Tomography: an eye into the coronary artery. Front Cardiovasc Med. 2022;9.

Prati F, Di Vito L, Biondi‐Zoccai G, Occhipinti M, La Manna A, Tamburino C, et al. Angiography alone versus angiography plus optical coherence tomography to guide decision-making during percutaneous coronary. Euro Intervent. 2012;8(7):823-9.

Prati F, Romagnoli E, Burzotta F, Limbruno U, Gatto L, La Manna A, et al. Clinical impact of OCT findings during PCI. JACC Cardiovasc Imaging. 2015;8(11):1297-305.

Chandra P, Sethuraman S, Roy S, Mohanty A, Parikh K, Gopalan BC, et al. Effectiveness and safety of optical coherence tomography-guided PCI in Indian patients with complex lesions: A multicenter, prospective registry. Indian Heart J. 2023;75(4):236-42.

Wijns W, Shite J, Jones MR, Lee SW, Price MJ, Fabbiocchi F, et al. Optical coherence tomography imaging during percutaneous coronary Intervention impacts physician decision-making: ILUMIEN I study. Eur Heart J. 2015;36(47):3346-55.