Evaluation of fine needle aspiration cytology in the diagnosis of soft tissue tumors and its correlation with histopathological findings

Authors

  • Ramesh Chandrakar Department of Pathology, Government Medical College, Rajnandgaon, Chhattisgarh
  • Riti Sharma Department of Pathology, Government Medical College, Rajnandgaon, Chhattisgarh
  • Renuka Gahine Department of Pathology, Pt. J. N. M. Medical College, Raipur, Chhattisgarh
  • Dhiraj Bhawnani Department of Community Medicine, Government Medical College, Rajnandgaon, Chhattisgarh

Keywords:

FNAC, Histopathology, Soft tissue tumor, Raipur, Chhattisgarh

Abstract

Background: Fine Needle Aspiration Cytology (FNAC) is a useful, safe and cost effective tool that is used in the diagnosis of lesions in various organs. Even though the literature on FNAC of soft tissue masses is relatively scarce, a large amount of interest has developed in this area in the last few years due to the low cost of the procedure, low incidence of complications, feasibility and high therapeutic efficiency. So the present study was undertaken to study the nature of various soft tissue tumors by FNAC and to compare the cytological diagnosis with the results obtained by biopsy.  

Methods: All cases 713 (Prospective-217 and Retrospective 496) included in present series were taken up for study. Aspiration of soft tissue lesions were performed following the technique of Zajicek et al. Smear was prepared, stained and examined. Histopathological details were available in 140 cases. Data was compiled in MS excel and checked for its completeness, correctness and then it was analyzed.

Results: Total number of 11,560 FNAC was done in six and half year’s period from 1st April 2003 to 30th September 2009. Out of the total 713 cases of soft tissue tumors, 71.25% were reported as benign and 28.75% as malignant. Soft tissue tumors were more common in males in comparison to females, with M: F-1.63:1. Accuracy of FNAC for benign and malignant soft tissue tumours was 88.1% and 92.9% respectively.  

Conclusion: The overall diagnostic accuracy of FNAC in the present study was found 90%. FNAC is a safe and reliable method of recognizing benign and malignant soft tissue tumors and in most instances histological sub typing is possible. Cytological diagnosis must be based on strict cytological criteria and well controlled ancillary techniques.

 

Metrics

Metrics Loading ...

References

Nagira K, Yamsmoyo T, Akisue T, Marui T, Hitora T, Nakatani T, et al. Reliability of fine needle aspiration biopsy in the initial diagnosis of Soft tissue lesions. Diagn Cytopathol. 2002;27:354-61.

Weiss SW, Goldblum JR. Soft tissue. In: Weiss SW, Goldblum JR, eds. Enzinger and Weiss’s Soft Tissue Tumour. 5th ed. US: Mosby; 2008.

Roy A, Sengupta S, Mallick MG, Bhattacharya A, Das S, Kundu B, et al. Cytodiagnosis of soft tissue lesions. J Cytol. 2003;20(2):89-93.

Zajicek J. The aspiration smear, In: Koss LG, eds. Diagnostic Cytology and its Histologic Bases. 3rd ed. Philadelphia: Lippincott; 1979: 1082-1100.

Koss LG. Stain techniques. In: Koss LG, eds. Diagnostic Cytology and its Histopathologic Basis. 1st ed. London: JB Lippincott; 1961.

Bezabih M. Cytological diagnosis of soft tissue tumors. Cytopathology. 2001;12:177-83.

Dey P, Malik MK, Gupta SK, Vashista RK. Role of fine needle aspiration cytology in the diagnosis of soft tissue tumors and tumor like lesions. Cytopathology. 2004;15(1):32-7.

Roy S, Manna AK, Pathak S, Guha D. Evaluation of fine needle aspiration cytology and its correlation with histopathologic findings in soft tissue tumors. J Cytol. 2007;24(1):37-40.

Pallock RE, Kainkell LH, Menck HR, Winchester DP. The national cancer data report on soft tissue sarcoma. Cancer. 1996;78:2247-57.

Rekhi B, Gorad, Kakade AC, Chinnoy RF. Scope of FNAC in the diagnosis of Soft tissue tumors: a study from a tertiary cancer referral center in India. Cytol J. 2007;4:20.

Barth RJ, Merino NJ, Solomon D, Young JC, Baker AR. A prospective study of the value of core needle biopsy and fine needle aspiration in the diagnosis of soft tissue masses. Surgery. 1991;112:536-43.

Wakely PE, Kneisl JS. Soft tissue aspiration cytopathology- Diagnostic accuracy and limitations. Cancer Cytopathol. 2000;90(5):292-8.

Layfield LJ, Anders KH, Glasgaw BJ, Mira JM. Fine needle aspiration of primary soft tissue tumors. Arch Pathol Lab Med. 1986;110:420-4.

Fletcher C, Kempson RL, Weiss SW. Association of directors of anatomic and surgical pathology’s recommendation for the reporting of soft tissue sarcoma. Hum Pathol. 1998;30:3-7.

Rasool Z, Bhat ML, Samoon N, Baba K, Rumana M, Reshi R, et al. Utility of fine needle aspiration cytology in diagnosis of soft tissue lesions with histopathological correlation. Glob J Med Public Health. (GJMEDPH). 2013;2(2):1-7.

Klijanieko J, Caillaud JM, Lagace R. Fine needle aspiration of primary and recurrent dermatofibrosarcoma protuberance. Diagn Cytopathol. 2004;30(4):261-5.

Domanski HA, Gustafson P. Cytologic features of primary, recurrent, and metastatic dermatofibrosarcoma protuberans. Cancer Cytopathol. 2002;96:351-61.

Dahl I, Hagmar B, Idvall I. Benign solitary neurilemmoma (Schwannoma). A correlative cytological and histological study of 28 cases. Acta Pathol Microbiol Immunol Scand A. 1984;92:91-101.

Hook SY, Jorda M, Mailhot S, Ganiei-Azar P. Fine needle aspiration cytology of superficial soft tissue lesions: a study of 110 cases. Acta Cytol. 1998;42:1289.

Downloads

Published

2017-01-07

How to Cite

Chandrakar, R., Sharma, R., Gahine, R., & Bhawnani, D. (2017). Evaluation of fine needle aspiration cytology in the diagnosis of soft tissue tumors and its correlation with histopathological findings. International Journal of Research in Medical Sciences, 3(3), 723–729. Retrieved from https://www.msjonline.org/index.php/ijrms/article/view/1365

Issue

Section

Original Research Articles