An in-depth analysis of the potential for healing with fish skin bandages

Monalisha Pal; Tushar Singh; Mukta; Raj Kiran

doi:10.18203/2320-6012.ijrms20242253

Authors

Monalisha Pal Department of Community Health Nursing, Sharda School of Nursing Science and Research, Sharda University, Greater Noida, U.P., India
Tushar Singh Department of Medical Surgical Nursing, Sharda School of Nursing Sciences and Researches, Sharda University, Gautam Buddha University, Noida, U.P, India
Mukta Department of Obstetrics and Gynaecology Nursing, Prakash Institute of Physiotherapy, Rehabilitation and Allied Medical Sciences. Greater Noida. U.P, India
Raj Kiran Department of Medical Surgical Nursing (Critical Care), Rayat Bahra College of Nursing, Hoshiarpur, Punjab, India

DOI:

https://doi.org/10.18203/2320-6012.ijrms20242253

Keywords:

Antimicrobial, Bandages, Fish skin, Natural remedies, Wound healing, Tissue regeneration

Abstract

Compared to typical bandaging materials, fish skin bandages have shown great promise as a wound treatment option. Fish skin is abundant, biocompatible, and naturally antibacterial, which makes it an ideal material for wound dressings. Moreover, fish skin shares a structure with human skin, which promotes improved integration with the wound bed and helps injured tissue regenerate. Fish skin bandages have emerged as a possible option for wound healing due to their unique biological features. This study examines the efficacy of fish skin bandages in wound treatment. Methods: This article attempts to understand the efficacy and mechanisms of action of fish skin bandages in encouraging wound healing by analyzing existing research, describing the biological makeup of fish skin, and investigating current investigations. Results: The results show that fish skin bandages have anti-inflammatory, antibacterial, and tissue-regenerative capabilities, making them an appealing solution for a variety of wounds Conclusion: The use of fish skin in wound treatment improves environmental sustainability by recycling fish waste. However, further study is needed to improve the manufacture, standardization, and therapeutic use of fish skin bandages.

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References

Ibrahim M, Ayyoubi HS, Alkhairi LA, Tabbaa H, Elkins I, Narvel R. Fish skin grafts versus alternative wound dressings in wound care: a systematic review of the literature. Cureus. 2023;15(3):36348.

Seth N, Chopra D, Lev-Tov H. Fish skin grafts with omega-3 for treatment of chronic wounds: exploring the role of omega-3 fatty acids in wound healing and a review of clinical healing outcomes. Surgical technology international. 2022;40:38-46.

Mathew-Steiner SS, Roy S, Sen CK. Collagen in Wound Healing. Bioengineering (Basel, Switzerland). 2021;8(5):63.

Yang CK, Polanco TO, Lantis JC. A prospective, postmarket, compassionate clinical evaluation of a novel acellular fish-skin graft which contains omega-3 fatty acids for the closure of hard-to-heal lower extremity chronic ulcers. Wounds: a compendium of clinical research and practice. 2016;28(4):112-8.

Alam K, Jeffery SL. Acellular fish skin grafts for management of split thickness donor sites and partial thickness burns: a case series. Military medicine. 2019;184:16-20.

Garrity C, Garcia-Rovetta C, Rivas I, Delatorre U, Wong A, Kültz D, Peyton J, Arzi B, Vapniarsky N. Tilapia fish skin treatment of third-degree skin burns in murine model. Journal of Functional Biomaterials.2023;14(10):512.

Wallner C, Holtermann J, Drysch M. The use of intact fish skin as a novel treatment method for deep dermal burns following enzymatic debridement: a retrospective case-control study. Eur. Burn J. 2022;3:43–55.

Lima Júnior EM, Moraes Filho MO, Forte AJ. Paediatric burn treatment using tilapia skin as a xenograft for superficial partial-thickness wounds: a pilot study. J Burn Care Res. 2020;41:241-7.

Lima EM, De Moraes Filho MO, Costa BA, Rohleder AVP, Sales Rocha MB, Fechine FV et al. Innovative Burn Treatment Using Tilapia Skin as a Xenograft: A Phase II Randomized Controlled Trial. J Burn Care Res. 2020;41(3):585-92.

Lullove EJ, Liden B, McEneaney P, Raphael A, Klein R, Winters C, JC LI. Evaluating the effect of omega-3-rich fish skin in the treatment of chronic, nonresponsive diabetic foot ulcers: penultimate analysis of a multicenter, prospective, randomized controlled trial. Wounds: a Compendium of Clinical Research and Practice. 2022;34(4):34-6.

Michael S, Winters C, Khan M. Acellular Fish Skin Graft Use for Diabetic Lower Extremity Wound Healing: A Retrospective Study of 58 Ulcerations and a Literature Review. Wounds. 2019;31(10):262-8.

Kirsner RS, Margolis DJ, Baldursson BT, Petursdottir K, Davidsson OB, Weir D, Lantis JC II Fish skin grafts compared to human amnion/chorion membrane allografts: a double-blind, prospective, randomized clinical trial of acute wound healing. Wound Repair Regen. 2020;28:75-80.

Stone R II, Saathoff EC, Larson DA. Accelerated wound closure of deep partial thickness burns with acellular fish skin graft. Int J Mol Sci. 2021;22:1590.

Wallner C, Holtermann J, Drysch M. The use of intact fish skin as a novel treatment method for deep dermal burns following enzymatic debridement: a retrospective case-control study. Eur. Burn J. 2022;3:43-55.

Zhao C, Feng M, Gluchman M, Ma X, Li J, Wang H. (2024). Acellular fish skin grafts in the treatment of diabetic wounds: Advantages and clinical translation. Journal of diabetes. 2024;16(5):135-54.