Melanosis secondary to Addison disease: a case report

Dhaval Dave, Anannya Mukherji, Manohar Joshi, Spandan Patel, Ashwini Jain, Ketan Pakhale, Archana Bhate

Abstract


Addison disease is a rare but potentially fatal disorder of the adrenal glands. Its manifestations are often confused with many common disorders, and a high index of suspicion is required for the diagnosis. In this case we observed that initially the manifestation were confused with melanosis secondary to consumption of Ayurvedic medication and pangastritis, but a high level of suspicion helped to reach the diagnosis of Addison disease.


Keywords


Addison disease, Rare case, Melanosis secondary to Ayurvedic medication, Pangastritis adrenal, Glucocorticoid, Mineralocorticoid

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References


Arlt W, Allolio B. Adrenal insufficiency. Lancet. 2003;361:1881-93.

Erichsen MM, Lovas K, Skinningsrud B, Wolff AB, Undlien DE, Svartberg J, et al. Clinical, immunological, and genetic features of autoimmune primary adrenal insufficiency: observations from a Norwegian Registry. J Clin Endocrinol Metab. 2009; 94:4882-90.

Bergthorsdottir R, Leonsson-Zachrisson M, Oden A, Johannsson G. Premature mortality in patients with Addison’s disease: a population- based study. J Clin Endocrinol Metab. 2006;91:4849-53.

Falorni A, Laureti S, De Bellis A, Zanchetta R, Tiberti C, Arnaldi G, et al. Italian addison network study: update of diagnostic criteria for the etiological classification of primary adrenal insufficiency. J Clin Endocrinol Metab. 2004;89:1598-604.

Ali J. Chakera. Addison disease in adults: diagnosis and management. Am J Med. 2010;123:409-13.