Reporting of serous effusions in accordance with Indian Academy of Cytology guidelines in a tertiary care centre: a 1-year study

Manish Gulia; Sandhya P. Gulia; Shivanshi S. Mittal; Surya Rana; Tathagat; Aaryan

doi:10.18203/2320-6012.ijrms20241877

Authors

Manish Gulia Department of Radio-diagnosis, Manipal Tata Medical College, Jamshedpur, Jharkhand, India
Sandhya P. Gulia Department of Pathology, Manipal Tata Medical College, Jamshedpur, Jharkhand, India
Shivanshi S. Mittal Adesh Medical College and Hospital, Kurukshetra, Haryana, India
Surya Rana Adesh Medical College and Hospital, Kurukshetra, Haryana, India
Tathagat Adesh Medical College and Hospital, Kurukshetra, Haryana, India
Aaryan Adesh Medical College and Hospital, Kurukshetra, Haryana, India

DOI:

https://doi.org/10.18203/2320-6012.ijrms20241877

Keywords:

IAC, Risk of malignancy, Serous effusion

Abstract

Background: The objective of the present study was to categorize serous effusions in accordance with the Indian Academy of Cytology (IAC) guidelines, evaluate the characteristics of various types of serous effusions using cytological findings, and determine the risk of malignancy within different diagnostic categories.

Methods: The study conducted at a tertiary care teaching hospital focused on patients with pleural, and peritoneal effusions/ascitic fluid, using retrospective data from patient records. Samples sent to the pathology department for cytopathological analysis over a one-year period after obtaining approval from institutional ethics committee (IEC). The statistical methods used included descriptive statistics and frequency analysis to examine the different cell types and characteristics present in the effusions. Risk of malignancy was calculated for each category. A Chi-square test was used to assess the relationship between different diagnostic categories, with a p value of <0.05 indicating statistical significance.

Results: The findings of the study indicate that out of a total of 161 cases, there were 127 (78.88%) male patients and 34 (21.12%) female patients, resulting in a male to female ratio of 18:5. Ascitic fluid was present in 103 cases (64%) and pleural fluid in 58 cases (36%). The majority of cases, 148 (91.92%), fell into the benign category, followed by 5 cases (3.10%) in category 3, 3 cases (1.86%) in category 5, 2 cases (1.24%) in category 4, and 3 cases (1.86%) in category 1. A statistically significant p value of 0.04 was found among the different diagnostic categories.

Conclusions: The IAC has specific guidelines and recommendations for reporting serous effusion cytology to ensure accurate and consistent interpretation of results. In conclusion, reporting serous effusion cytology according to IAC guidelines is essential for accurate diagnosis, prognostic information, quality assurance, communication with the healthcare team, and promoting research and education in the field. Adhering to these guidelines ensures standardized reporting practices and improves patient care outcomes.

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References

Nayar R, Wilbur DC, editors. The Bethesda System for Reporting Cervical Cytology: Definitions, Criteria and Explanatory Notes. 3rd edition. New York: Cham, Switzerland: Springer Press. 2015.

Nagose VB, Kamal MM, Kathuria SS, Laddhad SA. The Indian Academy of Cytologists Guidelines for Reporting Serous Effusion (IACGRSE): An Interobserver Agreement Analysis. J Cytol. 2022;39(3):121-5.

Srinivasan R, Rekhi B, Rajwanshi A, Pathuthara S, Mathur S, Jain D, Gupta N, et al, Prasoon Effusion Guidelines Committee of IAC Indian academy of cytologists guidelines for collection, preparation, interpretation, and reporting of serous effusion fluid samples. J Cytol. 2020;37:1-11.

Pergaris A, Stefanou D, Keramari P, Sousouris S, Kavantzas N, Gogas H, et al. Application of the International System for Reporting Serous Fluid Cytopathology with Cytohistological Correlation and Risk of Malignancy Assessment. Diagnostics (Basel). 2021;11(12):2223.

Crothers BA, Chandra A. Proceedings of the American Society of Cytopathology Companion Session at the 2019 United States and Canadian Academy of Pathology Meeting Part 1: Towards an International System for Reporting Serous Fluid Cytopathology. J Am Soc Cytopathol. 2019;8:362-8.

Chandra A, Crothers B, Kurtycz D, Schmitt F. Announcement: the international system for reporting serous fluid cytopathology. Acta Cytol. 2019;63(5):349-51.

Jha S, Sethy M, Adhya AK. Application of the Indian academy of cytologists recommendations for reporting serous fluid cytopathology in routine reporting of ascitic fluid specimen and assessment of the risk of malignancy. J Cytol. 2022;39:72‐7.

Kalita DJ, Thakuria SK. Indian Academy Of Cytology (IAC) Grading For Reporting Serous Effusions In A Tertiary Care Hospital Of North East India: A Three-Year Cross-Sectional Study. IJAR. 2023;13(12):10-2.

Kundu R, Srinivasan R, Dey P, Gupta N, Gupta P, Rohilla M, et al. Application of Indian academy of cytologists guidelines for reporting serous effusions: An institutional experience. J Cytol. 2021;38:1‐7.

Mercer RM, Corcoran JP, Porcel JM, Rahman NM, Psallidas I. Interpreting pleural fluid results. Clin Med (Lond). 2019;19:213-7.

Kalomenidis I, Light RW. Eosinophilic pleural effusions. Curr Opin Pulm Med. 2003;9(4):254-60.

Kala C, Kala S, Singh A, Jauhari RK, Bajpai A, Khan L. The International System for Reporting Serous Fluid Cytopathology: An Institutional Experience on its Implication and Assessment of Risk of Malignancy in Effusion Cytology. J Cytol. 2023;40(4):159-64.