An unusual presentation of gastrointestinal stromal tumour arising from the Ileum and involving the urinary bladder

Neeraj Kolap; Santosh Thorat; Akshay Mhase; Amol Rathod; Preet Shah

doi:10.18203/2320-6012.ijrms20242282

Authors

Neeraj Kolap Department of General Surgery, PCMC PGI YCM Hospital, Pimpri Pune, Maharashtra, India
Santosh Thorat Department of General Surgery, PCMC PGI YCM Hospital, Pimpri Pune, Maharashtra, India https://orcid.org/0009-0004-4801-4847
Akshay Mhase Department of General Surgery, PCMC PGI YCM Hospital, Pimpri Pune, Maharashtra, India
Amol Rathod Department of General Surgery, PCMC PGI YCM Hospital, Pimpri Pune, Maharashtra, India
Preet Shah Department of General Surgery, PCMC PGI YCM Hospital, Pimpri Pune, Maharashtra, India

DOI:

https://doi.org/10.18203/2320-6012.ijrms20242282

Keywords:

Bladder gist, Extraintestinal gist, Ileal gist, Imatinib therapy, GIST

Abstract

Gastrointestinal stromal tumours (GISTs) are mesenchymal tumours originating usually from stomach and small intestines, at times from unusual sites without GI (gastrointestinal) tract involvement. GISTs frequently occur among men in the age range of 60 to 65 years. These tumours are rarely symptomatic usually discovered incidentally on radiology or intraoperatively, diagnosis is confirmed on histology and IHC (immunohistochemistry). This instance represents an unusual presentation in a 65-year-old male who presented with symptoms of fatigue, per rectal bleed and dysuria due to an underlying infraumbilical tumour which was later diagnosed as a GIST arising from the ileum concurrently involving the urinary bladder, managed successfully with neoadjuvant Imatinib therapy followed by surgical resection.

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