Neuropsychiatric lupus: report of an interesting case with challenges in diagnosis and management

Divij Sharma; Varsha Patel; Preethi Jagannath; Saksham Sharma

doi:10.18203/2320-6012.ijrms20243382

Authors

Divij Sharma Department of Neurology, Bombay Hospital and Medical Research, Mumbai, Maharashtra, India
Varsha Patel Department of Neurology, Bombay Hospital and Medical Research, Mumbai, Maharashtra, India
Preethi Jagannath Department of Medicine, M. S. Ramaiah Medical College, Bangalore, Karnataka, India
Saksham Sharma Department of Medicine, University of Niš, Serbia

DOI:

https://doi.org/10.18203/2320-6012.ijrms20243382

Keywords:

Neuropsychiatric systemic lupus erythematosus, Autoimmune disease, Psychosis, Methylprednisolone

Abstract

NPSLE, an array of neurological and psychiatric symptoms within systemic lupus erythematosus (SLE), poses diagnostic challenges due to negative serology and absence of systemic signs. We present a 54-year-old woman with anemia, musculoskeletal pain, recurrent pleural effusion, and erratic behavior. Despite delayed identification, extensive testing finally revealed NPSLE. This case underscores the difficulty in linking diverse symptoms to SLE, resulting in delayed treatment initiation and adverse outcomes upon presentation.

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References

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